Covid and Vascular System, Endothelium, Blood Clots

Covid and Vascular System, Endothelium, Blood Clots

Morelaurieallee
"#persistent endothelial dysfunction"
SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells
SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells
US researchers found that SARS-CoV-2 spike protein causes endothelial cells to fuse into syncytia, weakening blood vessel barriers and potentially worsening COVID-19 complications.
#syncytia#endothelial inflammation#platelet endothelial cell adhesion molecule-1#persistent endothelial dysfunction#Endothelium#vascular#spike protein
·nature.com·
SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation

Long Covid patients exhibited persistent endothelial dysfunction.

This was indicated by lower venular flicker-induced dilation (vFID), narrower central retinal artery equivalent (CRAE), and lower arteriolar-venular ratio (AVR).

“Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients.”

#Long Covid#Endothelium#inflammation#vascular#retina#Eyes#persistent endothelial dysfunction
·link.springer.com·
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation