Covid and Vascular System, Endothelium, Blood Clots

Covid and Vascular System, Endothelium, Blood Clots

#vascular #Vascular #microclots #clots
Harriet Carroll: Recognise vax-induced long COVID on Twitter
Harriet Carroll: Recognise vax-induced long COVID on Twitter

Latest paper from Dr Robin Kerr & me: #LongCovid is primarily a Spike protein Induced Thrombotic Vasculitis https://researchsquare.com/article/rs-2939263/v1 Here we proposed that long covid is primarily a spike protein-induced thrombotic vasculitis, & we use Robin as a supporting case study 🧵 #TeamClots

·twitter.com·
Harriet Carroll: Recognise vax-induced long COVID on Twitter
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system - Cardiovascular Diabetology
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system - Cardiovascular Diabetology
More evidence that LongCOVID symptoms are due to widespread endothelial damage and a failed fibrinolytic system. We again found numerous entrapped inflammatory molecules; and this time also antibodies in microclots
·cardiab.biomedcentral.com·
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system - Cardiovascular Diabetology
Dr Claire Taylor on Twitter
Dr Claire Taylor on Twitter

1/A reminder that #LongCovid patients have microclots. We are sending children to school with no mitigations and a 5% chance of a disease that damages you blood vessels.🩸 ALL 80 patients tested in this paper had moderate microclots. Green is microclots.

·twitter.com·
Dr Claire Taylor on Twitter
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
“The result, as is strongly manifested in platelet-poor plasma (PPP) of individuals with Long COVID, is extensive fibrin amyloid microclots that can persist, can entrap other proteins, and that may lead to the production of various autoantibodies.”
·portlandpress.com·
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
Resia Pretorius on Twitter
Resia Pretorius on Twitter
Typical inflammatory conditions like cardiovascular disease, diabetes etc are known to have hypercoagulation - which is a hallmark of systemic inflammation. Microclots and platelet hyperactivation are both present in these conditions. Longcovid has significantly more microclots
·twitter.com·
Resia Pretorius on Twitter
James on Twitter
James on Twitter

Patient Anecdote thread on Twitter: Today I travelled 4000miles to get tested for Microclots to test the theory that this is causing my #longcovid symptoms. Turns out I have them. This testing needs to be made accessible to all those suffering around the world so they can be treated (1)

·twitter.com·
James on Twitter
WesElyMD on Twitter
WesElyMD on Twitter

Detailed analysis thread on Twitter: 1/🧵 Micro Clots & Endothelial Dysfunction in Long COVID

Plus new Epidemiology in @JAMA_current some say proves #LongCOVID is a hoax⁉️

Truth is…endothelial dysfunction plus inflammation can lead to life-altering brain & body dz.

Let’s explore data

·twitter.com·
WesElyMD on Twitter
Tiny, Menacing Microclots May Explain Long COVID’s Symptoms
Tiny, Menacing Microclots May Explain Long COVID’s Symptoms

“One core question is: Do these microclots actually represent a root cause, or are they in response to something else that's ongoing?” says Michael VanElzakker PhD, co-founder of PolyBio Research Foundation, which is focused on studying viral reservoir:

Tiny, Menacing Microclots May Explain Long COVID’s Symptoms

·webmd.com·
Tiny, Menacing Microclots May Explain Long COVID’s Symptoms
Hannah Davis on Twitter
Hannah Davis on Twitter

Anecdote: Big news: I was lucky to get tested for micro blood clots, & I have a lot of them! #LongCovid

Healthy control blood on the left. Mine on the right. The green is all microclots!

These clots are likely blocking oxygen from getting around my body & could explain many symptoms. 1/

·twitter.com·
Hannah Davis on Twitter