Covid and Viral Persistence

Covid and Viral Persistence

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Antiviral therapies for the management of persistent coronavirus disease 2019 in immunocompromised hosts: A narrative review
Antiviral therapies for the management of persistent coronavirus disease 2019 in immunocompromised hosts: A narrative review

ANTIVIRAL THERAPIES FOR PERSISTENT COVID/LONG COVID 83% SUCCESS 70 of 84 cases with the aggravating factor of immunosuppression

The types of treatment were grouped into: Prolonged Antiviral therapy Combination Antivirals Mixed therapy: Antiviral +Antibody

#antiviral#Viral Persistence#long covid
·onlinelibrary.wiley.com·
Antiviral therapies for the management of persistent coronavirus disease 2019 in immunocompromised hosts: A narrative review
Hey, folks. The Chinese government woke up years ago with the repurposing of Azvudine, producing nine billion pills that protected the thymus of their population and specifically targets HIV's Vif protein, preserving the CD4 population. The West chose to rot. End of story.
Hey, folks. The Chinese government woke up years ago with the repurposing of Azvudine, producing nine billion pills that protected the thymus of their population and specifically targets HIV's Vif protein, preserving the CD4 population. The West chose to rot. End of story.

Thread: Hey, folks. The Chinese government woke up years ago with the repurposing of Azvudine, producing nine billion pills that protected the thymus of their population and specifically targets HIV's Vif protein, preserving the CD4 population. The West chose to rot. End of story.

#Azvudine#antiviral#Viral Persistence
·x.com·
Hey, folks. The Chinese government woke up years ago with the repurposing of Azvudine, producing nine billion pills that protected the thymus of their population and specifically targets HIV's Vif protein, preserving the CD4 population. The West chose to rot. End of story.
MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID
MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID

Among other findings of this study, reactivation of viral herpes (EBV/CMV/HSV2) and CONFIRMED PERSISTENT SARS-CoV-2 INFECTIONS

This study is really about the diagnostic tool, and confirmation of viral persistence was part of proving the tool works. This is a step in the direction of a SarsCov2 test similar to HIV test.

#reactivation of other viruses
·medrxiv.org·
MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID
Infective SARS-CoV-2 in Skull Sawdust at Autopsy, Finland
Infective SARS-CoV-2 in Skull Sawdust at Autopsy, Finland

New study shows #SARSCoV2 in skull sawdust at autopsy in 22 deceased persons with confirmed #COVID19.

by PCR (2/22, 9.1%) and by culture (1/22, 4.5%) in skull sawdust, suggesting that live virus is present in tissues postmortem, including bone.

·wwwnc.cdc.gov·
Infective SARS-CoV-2 in Skull Sawdust at Autopsy, Finland
‘Visionary’ study finds inflammation, evidence of Covid virus years after infection
‘Visionary’ study finds inflammation, evidence of Covid virus years after infection
Investigators found long-lasting immune activation months and even years after infection. And, even more concerning, they report what looked like lingering SARS-CoV-2 virus in participants’ guts. Even those who’d had Covid but no continuing symptoms had different results than those who’d never been infected.
Investigators found long-lasting immune activation months and even years after infection. And, even more concerning, they report what looked like lingering SARS-CoV-2 virus in participants’ guts. Even those who’d had Covid but no continuing symptoms had different results than those who’d never been infected.
·statnews.com·
‘Visionary’ study finds inflammation, evidence of Covid virus years after infection
Presence of SARS‐CoV‐2 RNA in COVID‐19 survivors with post‐COVID symptoms 2 years after hospitalization: The VIPER study
Presence of SARS‐CoV‐2 RNA in COVID‐19 survivors with post‐COVID symptoms 2 years after hospitalization: The VIPER study
The SARS-CoV-2 VIrus PERsistence (VIPER) study investigated the presence of long-lasting SARS-CoV-2 RNA in plasma, stool, urine, and nasopharyngeal samples in COVID-19 survivors.
The SARS-CoV-2 VIrus PERsistence (VIPER) study investigated the presence of long-lasting SARS-CoV-2 RNA in plasma, stool, urine, and nasopharyngeal samples in COVID-19 survivors.
#Viral Persistence
·onlinelibrary.wiley.com·
Presence of SARS‐CoV‐2 RNA in COVID‐19 survivors with post‐COVID symptoms 2 years after hospitalization: The VIPER study
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms.
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms.
#Viral Persistence
·thelancet.com·
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms.
#Viral Persistence
·thelancet.com·
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
COVID-19 Virus Can Persist in the Body More Than a Year after Infection - PolyBio Research Foundation
COVID-19 Virus Can Persist in the Body More Than a Year after Infection - PolyBio Research Foundation
“The fact that every new SARS-CoV-2 infection has the potential to become chronic is perhaps the single most concerning aspect of this virus” says Dr. Amy Proal, President of PolyBio. “We have compelling data that viral persistence is much more common than recognized, which could have major health implications.”
#Viral Persistence
·polybio.org·
COVID-19 Virus Can Persist in the Body More Than a Year after Infection - PolyBio Research Foundation
Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection
Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection

These patients were given a monoclonal antibody to tag viral RNA, then sent through a PET scanner for imaging to show the persistence. Even patients that didn't have long cov*d had viral RNA. #viral persistence

·medrxiv.org·
Early Biological Markers of Post-Acute Sequelae of SARS-CoV-2 Infection
Use of total-body PET imaging to identify deep-tissue SARS-CoV-2 viral reservoirs and T cell responses in patients with Long COVID - PolyBio Research Foundation
Use of total-body PET imaging to identify deep-tissue SARS-CoV-2 viral reservoirs and T cell responses in patients with Long COVID - PolyBio Research Foundation
USE OF TOTAL-BODY PET IMAGING TO IDENTIFY DEEP-TISSUE SARS-COV-2 VIRAL RESERVOIRS AND T CELL RESPONSES IN PATIENTS WITH LONG COVID
#Long Covid#Viral Persistence
·polybio.org·
Use of total-body PET imaging to identify deep-tissue SARS-CoV-2 viral reservoirs and T cell responses in patients with Long COVID - PolyBio Research Foundation
laurie allee on Twitter
laurie allee on Twitter

AMAZING STUDY : MULTIPLE OMICRON SUB-VARIANTS in MULTIPLE TISSUE locations,

such as the lungs, heart, liver, kidneys, and intestines, both after primary infection and after reinfections

#Viral Persistence#reinfection
·twitter.com·
laurie allee on Twitter
Every Breaking Wave on Twitter
Every Breaking Wave on Twitter

Another recent paper on viral persistence

SARS-CoV-2 can remain for 100's of days (one instance 505 days @ detection), including autopsy, stool analysis, and other empirical bases

#Viral Persistence
·twitter.com·
Every Breaking Wave on Twitter
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Association of SARS-CoV-2 infection and persistence with long COVID
#Viral Persistence
·thelancet.com·
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"The presented evidence suggests that the duration of SARS-CoV-2 infection in patients can persist considerably longer than suggested"
#Viral Persistence#Long Covid
·thelancet.com·
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