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Frontiers | Real-world effectiveness and safety of nirmatrelvir-ritonavir (Paxlovid)-treated for COVID-19 patients with onset of more than 5 days: a retrospective cohort study
Frontiers | Real-world effectiveness and safety of nirmatrelvir-ritonavir (Paxlovid)-treated for COVID-19 patients with onset of more than 5 days: a retrospective cohort study

A study in Guangzhou, China, with 248 COVID-19 patients found that Paxlovid is effective and safe when given within 10 days of onset, reducing viral load

Effectiveness decreases after 10 days, but multiple cycles may help if the viral load remains high

·frontiersin.org·
Frontiers | Real-world effectiveness and safety of nirmatrelvir-ritonavir (Paxlovid)-treated for COVID-19 patients with onset of more than 5 days: a retrospective cohort study
Covid Drug Paxlovid Now Less Effective Than In Early Trials—But It’s Still Great At Preventing Death
Covid Drug Paxlovid Now Less Effective Than In Early Trials—But It’s Still Great At Preventing Death
Paxlovid—Pfizer’s antiviral Covid-19 treatment—is 37% effective at preventing hospitalization or death in high-risk patients compared with no treatment, according to a studypublished Thursday in the JAMA Network Open, well below the 88% effectiveness rate Pfizer and regulators reported in clinical trials in 2021
·forbes.com·
Covid Drug Paxlovid Now Less Effective Than In Early Trials—But It’s Still Great At Preventing Death
Paxlovid: Package Insert - Drugs.com
Paxlovid: Package Insert - Drugs.com

"Paxlovid is contraindicated with drugs that are highly dependent on CYP3A for clearance and for which elevated concentrations are associated with serious and/or life-threatening reactions"

See full list:

·drugs.com·
Paxlovid: Package Insert - Drugs.com
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If you think Paxlovid is like taking an antibiotic, take a look at the FDA sheet to see if you are one of the many who can not take it due to health contraindications or interactions with commonly prescribed drugs. Drug interactions alone are pp 9-15:
·fda.gov·
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