Long Covid/PASC (general)

#memory "#Post-Acute Conditions"
Temporal trajectories of long-COVID symptoms in adults with 22 months follow-up in a prospective cohort study in Norway
Temporal trajectories of long-COVID symptoms in adults with 22 months follow-up in a prospective cohort study in Norway

Norway study followed people for 22 months starting in March 2020 prior to infection. Memory and concentration problems persisted after infection, and didn't attenuate with time.

“Memory or concentration problems and dyspnoea were long-COVID symptoms. •
Other long-COVID symptoms were anosmia, dysgeusia and fatigue…

…This can have profound effects on everyday functioning. The fact that cognitive symptoms are persistent, and most of the population have been, or will be, infected by the SARS-CoV-2 virus, makes it crucial that further research focuses on the pathophysiology, and treatment”

·ijidonline.com·
Temporal trajectories of long-COVID symptoms in adults with 22 months follow-up in a prospective cohort study in Norway
Long Covid symptoms
Long Covid symptoms

Long Covid symptom severity based on number of reinfections. Symptoms are more severe upon the third and fourth infection. (Especially fatigue and memory decline.)

From November, 2024 Lancet “Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants”

·up.raindrop.io·
Long Covid symptoms
Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants
Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants

(MY NOTE: China vaccines are not MRNA technology. The better reduction in long-term Long Covid symptoms relative to multiple boosters compared to studies with MRNA patients is significant. Would like to see Long Covid data out of Cuba, a country that also did not use MRNA.)

“Analysis of 68,200 valid responses revealed that the most frequent long COVID symptoms include fatigue (30.53%), memory decline (27.93%), decreased exercise ability (18.29%), and brain fog (16.87%). These symptoms were less prevalent among those infected only once: fatigue (24.85%), memory decline (18.11%), and decreased exercise ability (12.52%), etc. Women were more likely to experience long COVID, with symptoms varying by age group, except for sleep disorders and muscle/joint pain, which were more common in older individuals. Northern China exhibits a higher prevalence of long COVID, potentially linked to temperature gradients. Risk factors included underlying diseases, alcohol consumption, smoking, and the severity of acute infection (OR > 1, FDR < 0.05). Reinfection was associated with milder symptoms but led to a higher incidence and severity of long COVID (OR > 1, FDR < 0.05). Vaccination, particularly multiple boosters, significantly reduced long-term symptoms by 30%–70% (OR < 1, FDR < 0.05). COVID-19 participants also self-reported more bacterial, influenza and mycoplasma infections, and 8%–10% of patients felt SARS-CoV-2-induced chronic diseases.”

·thelancet.com·
Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants