Frontiers | Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction
“We hypothesize that the key to LC pathogenesis lies in the presence of chronic functional damage to the main anti-inflammatory mechanisms of our body:
“The three reflexes mediated by
- The vagus nerve
- The hypothalamic-pituitary-adrenal(HPA) axis reflex.
- and the mitochondrial redox status.”