“PASC patients showed differences in brain activation in fatigue-related and additional regions. • PASC patients also had increased frontal task-related activation compared to controls. • Findings suggest PASC patients may exert more mental effort during demanding tasks.”

“In this population of healthy young adult US Marines with mostly either asymptomatic or mild acute COVID-19, one fourth reported physical, cognitive, or psychiatric long-term sequelae of infection. The Marines affected with PASC showed evidence of long-term decrease in functional performance suggesting that SARS-CoV-2 infection may negatively affect health for a significant proportion of young adults.”