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Frontiers | Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction
Frontiers | Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction

“We hypothesize that the key to LC pathogenesis lies in the presence of chronic functional damage to the main anti-inflammatory mechanisms of our body:

“The three reflexes mediated by

  • The vagus nerve
  • The hypothalamic-pituitary-adrenal(HPA) axis reflex.
  • and the mitochondrial redox status.”
#Long Covid#Post-Acute Conditions#vagus nerve#hypothalamic-pituitary-adrenal(HPA) axis reflex.#mitochondrial redox status#pituitary#Mitochondria#inflammation
·frontiersin.org·
Frontiers | Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction
Novel biomarkers of mitochondrial dysfunction in Long COVID patients
Novel biomarkers of mitochondrial dysfunction in Long COVID patients

New study on changes in mitochondria in Long Covid.

1️⃣Increased ROS (super oxide dismutase 1), … note Taurine can help counteract 2️⃣changes in mito recycling (mitophagy) and 3️⃣a potential biomarker: lower amounts of circulating free mito dna… could be used as a test

#Long Covid#Post-Acute Conditions#Mitochondrial Dysfunction#Mitochondria#taurine#increased ROS
·link.springer.com·
Novel biomarkers of mitochondrial dysfunction in Long COVID patients
Analysis of fat oxidation capacity during cardiopulmonary exercise testing indicates long-lasting metabolic disturbance in patients with post-covid-19 syndrome
Analysis of fat oxidation capacity during cardiopulmonary exercise testing indicates long-lasting metabolic disturbance in patients with post-covid-19 syndrome
“Post-COVID-19 Syndrome (PCS) is characterized by symptoms including fatigue, reduced physical performance, dyspnea, cognitive impairment, and psychological distress. The mechanisms underlying the onset and severity of PCS point to mitochondrial dysfunction as significant contributor. This study examined fat oxidation as a function of mitochondrial capacity during exercise.”
#Long Covid#Post-Acute Conditions#Mitochondria#mitochondrial damage#exercise#cognitive decline#cognition#fatigue#psychological distress#mental health#Heart#lungs#Cell Damage#Cardiopulmonary Exercise Testing#fat oxidation
·clinicalnutritionjournal.com·
Analysis of fat oxidation capacity during cardiopulmonary exercise testing indicates long-lasting metabolic disturbance in patients with post-covid-19 syndrome