“We hypothesize that the key to LC pathogenesis lies in the presence of chronic functional damage to the main anti-inflammatory mechanisms of our body:

“The three reflexes mediated by

• The vagus nerve
• The hypothalamic-pituitary-adrenal(HPA) axis reflex.
• and the mitochondrial redox status.”

“Between 2% and 14% of COVID survivors develop a syndrome called postural orthostatic tachycardia syndrome (POTS) (1).

However, it is commonly attributed to stress and anxiety.

This is the surprising story of how POTS (and possibly Long COVID) might be linked to an even rarer syndrome...🧵”