LongCovidPharmD on Substack
summary of a Harvard preprint of a long covid patient survey addressing patient responses to a variety of possible Long Covid treatments
Anyone else have musical auditory hallucinations w ? Also having more trouble identifying objects (as in I see a shape of something and briefly think it is something else). Coming up on year 5 & the brain damage seems pretty progressive.
“Anyone else have musical auditory hallucinations w #LongCovid? Also having more trouble identifying objects (as in I see a shape of something and briefly think it is something else). Coming up on year 5 & the brain damage seems pretty progressive.”
Mitochondrial dysfunction in acute and post-acute phases of COVID-19 and risk of non-communicable diseases
Up to 70% of SARS-CoV-2 infected have reduced organ function for 4 months or more after infection, which leads to an increased risk of developing chronic diseases in e.g. lungs, kidneys and the cardiovascular system.
“Even though the etiology of COVID-19 is complex and there are multiple factors involved, decreased organ function has been associated with mitochondrial dysfunction for both the acute phase and post-acute phase of COVID”
Why scientists say every new infection puts you at risk of getting long COVID
“The 34-year-old Overland Park pharmacist is one of 17 million Americans battling long COVID, an amorphous constellation of symptoms that scientists are only beginning to understand and most doctors are struggling to treat.”
The 34-year-old Overland Park pharmacist is one of 17 million Americans battling long COVID, an amorphous constellation of symptoms that scientists are only beginning to understand and most doctors are struggling to treat.
Between 2% and 14% of COVID survivors develop a syndrome called postural orthostatic tachycardia syndrome (POTS) (1).
“Between 2% and 14% of COVID survivors develop a syndrome called postural orthostatic tachycardia syndrome (POTS) (1).
However, it is commonly attributed to stress and anxiety.
This is the surprising story of how POTS (and possibly Long COVID) might be linked to an even rarer syndrome...🧵”
BCG Vaccine May Protect Against Long COVID Symptoms
A vaccine that prevents tuberculosis & other mycobacterial infections as well as bladder cancer may prevent Long Covid.
A Phase 3 clinical trial found it decreased the likelihood of hearing/sleeping/concentration/memory/vision issues after COVID:
Distinguishing features of long COVID identified through immune profiling
“Post-acute infection syndromes may develop after acute viral disease1. Infection with SARS-CoV-2 can result in the development of a post-acute infection syndrome known as long COVID. Individuals with long COVID frequently report unremitting fatigue, post-exertional malaise, and a variety of cognitive and autonomic dysfunctions2,3,4. However, the biological processes that are associated with the development and persistence of these symptoms are unclear. Here 275 individuals with or without long COVID were enrolled in a cross-sectional study that included multidimensional immune phenotyping and unbiased machine learning methods to identify biological features associated with long COVID.”
Post-acute infection syndromes may develop after acute viral disease1. Infection with SARS-CoV-2 can result in the development of a post-acute infection syndrome known as long COVID. Individuals with long COVID frequently report unremitting fatigue, post-exertional malaise, and a variety of cognitive and autonomic dysfunctions2,3,4. However, the biological processes that are associated with the development and persistence of these symptoms are unclear. Here 275 individuals with or without long COVID were enrolled in a cross-sectional study that included multidimensional immune phenotyping and unbiased machine learning methods to identify biological features associated with long COVID.
Actor Tilda Swinton was unable to get out of bed for three weeks due to a SARS-CoV-2 infection.
“I was coughing like an old gentleman who smoked a pipe for 70 years, and had nasty vertigo,” Tilda said. “... the worst thing is how it affected my brain.”
When Athletes, Entertainers, & Other Notable People Get Long Haul COVID+
When Athletes, Entertainers, & Other Notable People Get Long Haul COVID+
PostMay 251 min readWhen Athletes, Entertainers, & Other Notable People Get Long Haul COVID+
When Athletes, Entertainers, & Other Notable People Get Long Haul COVID+
To all the community I have some important news (not to my condition unfortunately):
“Video art pieces name: ‘Trapped in Body and Time: Living the Reality of Severe ME/CFS and Long COVID’
This exhibition is especially meaningful because The Holy Art Gallery has a strong reputation and significant reach on social media, which means this piece has the potential to bring much-needed visibility to severe ME/CFS and Long COVID. I hope it helps amplify our voices.”
‘I was in denial about it’: actor Matt McGorry on having long Covid
“The science is really clear getting Covid over & over again is not good for anyone. It feels like where the climate movement was 10 years ago, where scientists were saying things & people were not really listening.”
Frontiers | A blood-based mRNA signature distinguishes people with Long COVID from recovered individuals
“Seventy genes were identified as significantly up- or down-regulated in Long COVID samples, and the vast majority were downregulated. The most significantly up- or downregulated genes fell into two main categories, either associated with cell survival or with inflammation. This included genes such as ICOS (FDR p = 0.024) and S1PR1 (FDR p = 0.019) that were both up-regulated, indicating that a pro-inflammatory state is sustained in Long COVID PBMCs compared with COVID recovered PBMCs”
Matt McGorry Shares How Long COVID-19 Has ‘Massively Impacted’ His Life
“don’t share this to scare people, but [because] I now recognize that I was living in denial [because] of how badly I wanted COVID to be over," he continued. "I hope that you can learn from my experience."
"People said that AIDS was psychosomatic. This is the same thing you hear about COVID and Long COVID. It's shocking to hear people repeat this
“People said that AIDS was psychosomatic. This is the same thing you hear about COVID and Long COVID. It's shocking to hear people repeat this then say that they're liberals or leftists."
Long COVID is becoming a serious social and economic issue for Australia
“Long COVID is becoming a serious social and economic issue for Australia…Addressing this health challenge is vital to getting many people back participating fully in their lives”
Four years on from the pandemic and long Covid’s inequalities have only worsened
“Four years on from the pandemic and long Covid’s inequalities have only worsened Fatigue, cognitive difficulties, and breathlessness are still a daily reality for many. It is particularly acute in poorer communities”
Four years on from the pandemic and long Covid’s inequalities have only worsened
Fatigue, cognitive difficulties, and breathlessness are still a daily reality for many. It is particularly acute in poorer communities
Dr. Jeffrey Kopin: Younger adults have worse long COVID symptoms
a new Northwestern study that shows younger and middle-aged adults have worse long COVID symptoms than older adults
a new Northwestern study that shows younger and middle-aged adults have worse long COVID symptoms than older adults
Interventions for the management of long covid (post-covid condition): living systematic review
No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty). We're still in desperate need for a validated treatment
Moderate certainty evidence suggests that CBT and physical and mental health rehabilitation probably improve symptoms of long covid.
I developed long covid & my dad died after our covid infection JUST LAST YEAR. There have been over a million dead from COVID during your presidency, w tens of millions disabled. This is what our family looked like a year AFTER you declared the pandemic over:
“I developed long covid & my dad died after our covid infection JUST LAST YEAR. There have been over a million dead from COVID during your presidency, w tens of millions disabled. This is what our family looked like a year AFTER you declared the pandemic over:
This year I unfortunately got POTS from COVID. POTS is a failure of the body to regulate blood flow correctly, the heart has to beat extra fast to get blood to reach the head when upright. It’s much more complicated than that but that’s the defining symptom.
One of the world's foremost AI researchers is now struggling with long COVID.
We are destroying hearts and minds letting Covid rip and rip and rip.
Another one. Nothing to see here…
"Don't Sleep on Your Power" Senator Lindsey Port on Long COVID Advocacy
Opinion | Donate This Holiday Season: Long Covid Research Need Your Help
“For people with debilitating long Covid, the new year heralds a cruel anniversary: Some are experiencing their fifth year with the agonizing illness. And despite the roughly $1.6 billion that the National Institutes of Health has received for long Covid research, not a single drug has yet been approved for that purpose.”
For people with debilitating long Covid, the new year heralds a cruel anniversary: Some are experiencing their fifth year with the agonizing illness. And despite the roughly $1.6 billion that the National Institutes of Health has received for long Covid research, not a single drug has yet been approved for that purpose.
【Long COVID】About Symptoms And Treatments / If You Think You Have Symptoms of Long COVID （English）
“Persistent or new symptoms as Long COVID may occur in all infected person. In this video,we will explain about the symptoms and treatments, what to do if you think you may have symptoms if Long COVID.”
Everything Wrong with Canada's Proposed Long COVID Recommendations
“The proposed Canadian guidelines for treating Long COVID pose harm to patients and risk psychologizing the disease.”
The proposed Canadian guidelines for treating Long COVID pose harm to patients and risk psychologizing the disease.
Sluggish gas exchange in the lungs may be involved in long-COVID brain fog | CIDRAP
“Lower rates of gas exchange in the lungs may contribute to impaired cognitive function ("brain fog") tied to long COVID, according to a small study to be presented at next week's Radiological Society of North America's (RSNA's) annual meeting in Chicago.
Pulmonary gas exchange is the movement of oxygen from the lungs to the bloodstream and carbon dioxide from the bloodstream to the lungs.”
A new definition of Long COVID
“Long COVID is not a psychological condition,” Becker said. “It is a medical condition, and it should be treated as such.”
Long COVID Hits the Young Harder Than the Old, Study Finds
“Long COVID Hits the Young Harder Than the Old, Study Finds”
Long COVID Hits the Young Harder Than the Old, Study Finds
Whole health system approach to long covid 080122 final
Whole Health System Approach to Long COVID Patient-Aligned Care Team (PACT) Guide U.S. Department of Veterans Affairs
Video essay: Taipei on what it’s like being a drag artist with Long COVID - The Sick Times
“Video essay: Taipei on what it’s like being a drag artist with Long COVID”
Video essay: Taipei on what it’s like being a drag artist with Long COVID