We have previously reported on the complicated naming issues surrounding biosimilar products and how biological qualifiers, such as three or four-letter codes, should be added to distinguish between them. However, the naming of the original biologic drug product is well established, as outlined by the World Health Organization (WHO), and...Read More

Chemotherapy (chemo) is a treatment of cancer-killing drugs used to kill chronic myeloid leukemia cells. Learn more about chemotherapy here.

Hi everyone, Liz here (+1 662 830 8246, info@nakedactives.com) Epidermal Growth Factor (EGF) serum is one of the most effective formulae to repair the skin and provide deep moisture and hydration. EGF serums  rejuvenate and produce glowing skin all while repairing the skin's elasticity. It is important to know how to use EGF serum properly to ensure the skin is treated correctly.   Click to Explore Naked Actives EGF Serum Regular application of EGF improves the appearance of the skin by making it smoother and radiant. Our skin requires hydration to look refresh and healthy. The serum penetrates the skin perfectly and works well on damaged skin. It smooths the skin as well as makes it glowing. Learn more about EGF serum and how to use EGF serum. How to Use an EGF Serum Effectively? It is important to know how to use a serum, as each one has its own impact on the skin and anticipating how your skin responds to it is essential.Use the skin serum regularly, once in the morning and then again in the evening, before applying your moisturizer. Below are the ways how to use EGF serum:  It is easiest for the serum to penetrate the skin when it's clean and slightly moist, so before applying the EGF serum make sure to cleanse the skin. To open up the pores, apply a lukewarm towel to moisten the skin so that the pores open easily. Take a few drops of the EGF serum on your fingertips and apply onto the skin by gently blending it into the pores. Do not stretch or rub your skin harshly or forcefully, keep it gentle and soft. Massage the skin for just a few minutes to ensure that the serum has absorbed into the skin. Use the tips of your fingers lightly on both sides and gently let it get absorbed. As you rub the skin lightly, the serum will go into the deeper layers of the skin. If you feel a tingling sensation then it can be a sign the active ingredients in the serum are getting to the dermis – where they need to be if they are going to work. Once the serum gets completely absorbed, you can now apply your other makeup products. Benefits of EGF Serum EGF serum has wonderful benefits on the skin, maintaining the elasticity of the skin by keeping it radiant, moisturized and smooth. Below are some more benefits of EGF serums: Anti-aging formula - EGF serum contains anti-aging qualities that can help to maintain youthful skin. The application of EGF serums works effectively on fine lines, wrinkles, blemishes, etc. and leaves you with radiant glowing skin. Reconstructs the skin cells - EGF serums treat damaged skin and construct the skin cells to speed healing and protect against radicals. They also activate new skin cells which ultimately deliver rejuvenated skin. Hydrates the skin - EGF serum reduces fine lines, minimizes wrinkles, and brightens texture, by providing hydration and moisture to the skin, also turning it smooth and supple. Radiant glow - This is definitely this is one of the amazing perks you will enjoy from using the EGF serum as it provides immense glow to the skin and lightens the blemishes & dark circles. Conclusion The above information is all about what is EGF serum and how to use EGF serum. After going through this article you will have learned the correct usage of EGF serum and which directions to use for its application. You can also see there are many major benefits of using EGF serum that will definitely rejuvenate your skin. Its immense formula works on the skin gently and provides you with beautifully healthy & radiant skin.

What's in a name? When it comes to the 'mabs,' 'mibs,' and 'nibs' of biologic drugs, more than you may think.

Science’s most powerful ingredients are better together.

Epidermal growth factor (EGF) and EGF receptor (EGFR) play an essential role in wound healing through stimulating epidermal and dermal regeneration. The development of new therapies for enhancing wound healing has included the use of EGF. In addition, ...

Spleen tyrosine kinase (Syk) is a cytosolic non-receptor protein tyrosine kinase (PTK) and is mainly expressed in hematopoietic cells. Syk was recognized as a critical element in the B-cell receptor signaling pathway. Syk is also a key component in signal transduction from other immune receptors like Fc receptors and adhesion receptors. Several oral Syk inhibitors including fostamatinib (R788), entospletinib (GS-9973), cerdulatinib (PRT062070), and TAK-659 are being assessed in clinical trials. The second generation compound, entospletinib, showed promising results in clinical trials against B-cell malignancies, mainly chronic lymphoid leukemia. Syk inhibitors are being evaluated in combination regimens in multiple malignancies.

B-cell receptor (BCR) associated kinases including spleen tyrosine kinase (SYK) contribute to the pathogenesis of B-cell malignancies. SYK is persistently phosphorylated in a subset of non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), ...

Inhibition of SYK kinase activity impinges on various innate and adaptive immune responses. RO9021 could serve as a starting point for the development of selective SYK inhibitors for the treatment of inflammation-related and autoimmune-related disorders.

Since the development of imatinib and other tyrosine kinase inhibitors (TKIs), the prognosis for patients with chronic myeloid leukemia (CML) has markedly improved, such that most patients diagnosed with CML can now expect to live with their disease rather ...

A comprehensive guide to side effects including common and rare side effects when taking Hydrea (Hydroxyurea) includes uses, warnings, and drug interactions.

Large-cap biopharma Alexion Pharmaceuticals, Inc. (NASDAQ: ALXN) announced a deal Tuesday to buy its small-cap peer Portola Pharmaceuticals Inc (NASDAQ: PTLA). The news comes...

Nearly four years removed from a disastrous sales fraud probe and an overhaul of its senior leadership, Alexion has launched a dealmaking campaign to bolster its rare disease pipeline. But one activist investor thinks Alexion's strategy is ill-conceived—and the old foe is airing its grievances in public.

Portola Pharmaceuticals Inc. won a partial reprieve in a securities lawsuit, but investors can “almost certainly” fix the flaws in their loss causation allegations by amending their complaint, a federal judge in California said.

Portola discovers developis therapies that transform lives and patient care by changing treatment paradigms in thrombosis and hematologic diseases.

A federal judge in San Francisco said shareholders of Portola Pharmaceuticals Inc can move forward with their lawsuit accusing the company and its underwriters of misrepresenting its financial position ahead of a 2019 securities offering.

Alexion will pay $18 per share for Portola, which closed at $7.76 per share on Monday.

Portola Pharmaceuticals is a global, commercial-stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics that could significantly advance the fields of thrombosis and other hematologic conditions.

Alexion Pharmaceuticals made a move to acquire Portola Pharmaceuticals.