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Dr. Ryan Goodwin, Director, Cleveland Clinic Center for Pediatric Orthopaedics and Scoliosis Surgery is joined by physical therapists Raquel Griffis, PT, DPT and Lisa Seely, PT to discuss the changes that occur to the musculoskeletal system with Marfan Syndrome, treatment options, when to seek a physical therapist (PT), how to work with a PT, and a case presentation of a child with Marfan. Filmed at the Regional Symposium on Marfan Syndrome and Related Disorders presented by Cleveland Clinic and The Marfan Foundation

High arterial tortuosity may signify early arterial pathology which may precede development of intracranial aneurysms. We measured arterial tortuosity of intracranial vessels and reviewed the medical records of three groups of patients: with intracranial ...

The tortuosity index of intracranial arteries is an easily calculated and highly reproducible measure, which shows a high specificity for Marfan syndrome and Loeys-Dietz syndrome and may be useful in differentiating these 2 entities.

There is a general assumption in the cerebrovascular literature that there is an association between carotid artery tortuosity and connective tissues disease; however, this has not been firmly established. The purpose of this study was to determine the ...

kidney cysts seems to be linked to an increased aortic dissection risk,,,

According to this study the drug Irbesartan reduces aortic dilatation in children and young adults with Marfan syndrome.

Find symptoms and other information about Marfan syndrome type 1.

Marfan Syndrome. Introduction & Overview. What is Marfan Syndrome?. Connective Tissue Disorder Malformation of Chromosome 15 Affects bodily structures: Skeleton Lungs Eyes Heart Blood vessels. What is Connective Tissue?. “Cellular Glue”

Postural orthostatic tachycardia syndrome, or POTS, is a little known and often undiagnosed disorder that can cause racing heart, dizziness and other symptoms.

Simple, specific diagnostic list

A full length video discussing all aspects of Marfan Syndrome by Dr Child MD Marfan Trust

Marfan syndrome is a condition that affects the connective tissues of the entire body, including joints, eyes, heart, blood vessels, lungs, bones & spinal cord.

Marfan Syndrome (MFS) is a systemic disorder caused by mutations in fibrillin-1. The most common cause of mortality in MFS is dissection and rupture of the aorta. Due to a highly variable and age-dependent clinical spectrum, the diagnosis of MFS still ...

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Lack Lysine, making flax seeds an incomplete protein. Contain phytic acid which reduces absorption of iron & zind. Therefore should not be eaten at same meal as those.

Need lysine to make complete protein.

Eating the right foods can help you manage iron-deficiency anemia. Find out what is best to eat and what is best to avoid.

Marfan syndrome (MFS), a multisystemic connective disorder, caused by fibrillin 1 gene mutations with autosomal dominant inheritance. The disease spectrum is wide and the major causes of death are related to aortic root aneurysm or dissection. The purposes ...

Marfan syndrome is an autosomal dominant, multisystem disease characterized by long bone overgrowth and other skeletal abnormalities, dislocation of the ocular lens, pneumothorax, decreased skeletal muscle mass, mitral valve prolapse, and dilatation of the aortic root. Antoine Bernard-Jean Marfan first described the syndrome in 1896 in a young patient with peculiarly long and thin digits (subsequently termed arachnodactyly), elongated limbs (which he termed dolichostenomelia), and congenital contractures of multiple joints. Because of the latter feature, this patient may really have had congenital contractural arachnodactyly, a connective tissue disorder not described until 1968. For the half century subsequent to Marfan’s report, features in other systems were described in patients with thin, elongated limbs: mitral valve disease in 1912; dislocation of the ocular lens in 1914; ruptured aortic aneurysm in 1918; aortic root dilatation and dissection in 1943; and autosomal dominant inheritance in 1949. Manifestations occur in many other tissues and organs and are increasingly being recognized as patients survive to older ages.1

WebMD's guide to Marfan syndrome, an inherited disease that affects the heart.

Marfan syndrome is a genetic disease affecting the body's connective tissues, causing problems with the heart and blood vessels, eyes, and bones.

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Studies have shown that reducing the amount of salt in your diet can improve Overactive Bladder symptoms. Learn more today!

Vitamin B12–deficiency anemia develops when your body can't make enough healthy red blood cells because it doesn't have enough vitamin B12. Learn about its’ causes, symptoms, and treatments.

Metformin can cause vitamin B12 deficiency. The effect metformin can have on your B12 levels depends on how long you’re undergoing therapy as well as other factors.