7. Roots to Sky: Clinical Research & Treatment

Northwestern University researchers have uncovered how ketamine delivers rapid and prolonged depression relief by activating new neurons for immediate effects and increasing their production for lasting benefits. This breakthrough could lead to safer, ketamine-inspired antidepressants.

Objectives: To assess the evidence for the efficacy of acupuncture for non-specific low back pain (NSLBP), compared with sham or placebo therapies. Methods: We ...

My research focus is on arthropod vector- host-pathogen interactions. I aim to understand at the molecular level how pathogen infection levels are sustained in

Plus, the basic ways to support cognitive longevity.

It could also help find new treatments.

These three Canadians say they are struggling with a chronic form of Lyme disease and feel abandoned by a health-care system divided over how to diagnose and treat the expanding illness.

Recent research has unveiled a new potential concern associated with PCOS: cognitive decline in midlife. Learn about the link between PCOS and cognitive decline and next steps in research.

The results are promising, but more research is needed.

Inspired by Cao et al 2023.[1] With thanks to Deniah for the image. EA – electroacupunctureIR – insulin resistancePCOS – polycystic ovary syndromeBMI – body mass indexHOMA-IR – homeostatic model as…

Gutierrez Ruiz et al. analyzed the lysosomal proteome of pancreatic cancer cells expressing oncogenic KRAS. They identified the GEF DOCK8 as being aberrantly expressed in pancreatic cancer cells, where it controls lysosome morphology. DOCK8 regulates lysosomal actin, which impacts trafficking and secretion of lysosomal cathepsins to promote tumor cell invasion.

How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo Clinic researchers studying pancreatic cancer—the third deadliest form of cancer in the U.S.—recently made a discovery that advances knowledge of how metastasis unfolds. They identified a cell-signaling protein that drives pancreatic cancer cell growth that could be a potential therapeutic target.

Brief doze may delay brain shrinkage, which occurs faster in people with neurodegenerative diseases

COVID + THE BRAIN 🧠 There’s been a flurry of new studies published in recent weeks about Covid’s detrimental impact on the brain.This is the aspect of Covid which concerns me most, but which many people seem to be blissfully unaware of.So let’s dig into what we know… 🧵 pic.twitter.com/RnUfGFCImt— Cat in the Hat 🐈‍⬛ 🎩 🇬🇧 (@_CatintheHat) March 2, 2024

Scientists have developed a machine learning model that predicts Alzheimer's onset up to seven years early, identifying high cholesterol and osteoporosis as key predictors, especially in women. Published in Nature Aging, this study marks a significant step toward early diagnosis and understanding of Alzheimer's.

A revised CDC reporting system led to a 70 percent increase in reported cases of Lyme disease, but experts say more can be done.

Hye Kyung Baek*, Young Jun Kim, Yeon Sun Lee, Hye Ri Jo, Mi So Park, Dong Guk Shin, Hyun A Shim. Journal of Acupuncture Research 2022;39:275-82. https://doi.org/10.13045/jar.2022.00206

Heading to the bar? Read this first.

"Following this diet is associated with lower risk of cognitive decline.”

Many cancer patients seek adjunctive therapies to biomedical cancer treatments at some point of their disease trajectory. While acupuncture is increas…

But if I told you this two decades ago, you’d think I’m crazy.

A new study may now provide a greater explanation for why many experience prolonged fatigue following COVID-19 infection.

The number of older people, including those living with dementia, is rising, as younger age mortality declines. However, the age-specific incidence of dementia has fallen in many countries, probably because of improvements in education, nutrition, health care, and lifestyle changes. Overall, a growing body of evidence supports the nine potentially modifiable risk factors for dementia modelled by the 2017 Lancet Commission on dementia prevention, intervention, and care: less education, hypertension, hearing impairment, smoking, obesity, depression, physical inactivity, diabetes, and low social contact.

Welcome to Evidence Based Acupuncture, a non profit organization source for acupuncture’s scientific evidence, featuring acupuncture evidence summaries.