Mood & Mind

A simple—but experimental—treatment gave me my brain back.

Could psychedelics lead to improved antidepressant or antianxiety therapies?

Drug combination targeting lax airways is nearing an FDA submission

Glyceraldehyde links chronic stress to depression by driving inflammation and telomere shortening, offering a potential biomarker for diagnosis and treatment.

Alzheimer’s disease is traditionally seen as a brain disorder, but new research using fruit flies reveals that it also affects organs and tissues throughout the body.

New findings suggest that dysfunction in the brain’s glymphatic system—a key waste clearance pathway—may contribute to cognitive impairments in adults with ADHD, shedding light on a lesser-known biological mechanism behind the disorder.

A research team has unveiled the cause and molecular mechanism of chronic brain inflammation that results in repetitive behavioral disorders. The research team demonstrated that an inflammatory response ...

People with depression who were more optimistic at the start of treatment—and whose optimism increased during treatment—were more likely to benefit from SSRIs, according to a recent study, raising the possibility of tailoring treatments based on psychological traits.

Leading ADHD experts give real-life answers to questions submitted by ADD adults and parents raising children with attention deficit disorder across a range of topics covering symptoms, school, work, and family life. Download the accompanying slide presentations here: additudemag.com/adhd-expert-webinars-index (look for the episode number). Note on audio quality: This podcast is a recording of a webinar series, and the audio has been captured from conversations recorded via a computer or telephone, not in a studio. Register to participate in the live webinars at: additudemag.com/tag/webinar.

A new study suggests that perceived stress and depression factor into the relationship between insomnia and hazardous drinking -- perhaps not a surprise. But because the relationship between insomnia and heavy drinking goes in both directions, the influence of stress or depression depends on which condition came first, the analysis found.

A University of Exeter study finds a new treatment for depression could be a "significant advance".

A new treatment for depression, Stanford neuromodulation therapy, works eight times faster than the currently approved protocol and causes remission in nearly 80 percent of patients, according to recent research.

Depression is a very complex disorder and we simply have no good evidence that antidepressants help sufferers to improve

If phase 3 trials of MM120 (lysergide d-tartrate) for anxiety and depression are successful, could the LSD-based drug become the first FDA-approved psychedelic?

Scientists found that sleep plays an active role in transforming how memories are stored. After an immersive experience, participants remembered the order of events better after sleeping, suggesting the brain prioritizes storylines over details during deep sleep.

A pioneering clinical study found that pairing vagus nerve stimulation (VNS) with traditional therapy eliminated PTSD diagnoses in all participants up to six months post-treatment.

New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.

New data challenge old beliefs — get the latest on alcohol’s role in cancer, cognitive decline, and mental health. Learn how to update AUDIT use, patient talks, and prescribing practices.

Join a discussion with the experts for an enlightening journey into the intricate world of managing patients with bipolar depression. Credit available for th...

A surprising discovery in spider brains has led scientists to uncover a hidden waste removal system in the human brain. Its breakdown may explain the progressive neuron loss seen in Alzheimer’s disease, offering a new target for early intervention.

Despite claims that antidepressants may be just delivering a placebo effect, three-quarters of people who tried them in a large study said they helped

Brain imaging, known as functional MRI, combined with machine learning can predict a treatment response based on one's depression "biotype."