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Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Clostridioides difficile (C. diff.) infection (CDI) is a leading cause of hospital acquired diarrhea in North America and Europe and a major cause of morbidity and mortality. Known risk factors do not fully explain CDI susceptibility, and genetic susceptibility is suggested by the fact that some pat …
·pubmed.ncbi.nlm.nih.gov·
Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Vancomycin in the treatment of inflammatory bowel disease: there is a role beyond Clostridioides difficile infection - PubMed
Vancomycin in the treatment of inflammatory bowel disease: there is a role beyond Clostridioides difficile infection - PubMed
The development of new biological agents and small molecules has revolutionized the treatment of Inflammatory Bowel Disease (IBD). However, many patients do not respond or gradually lose their response, necessitating the search for other therapeutic strategies (1). In this clinical case, we describe …
·pubmed.ncbi.nlm.nih.gov·
Vancomycin in the treatment of inflammatory bowel disease: there is a role beyond Clostridioides difficile infection - PubMed
Identification of Micrococcin P2-Derivatives as Antibiotic Candidates against Two Gram-Positive Pathogens - PubMed
Identification of Micrococcin P2-Derivatives as Antibiotic Candidates against Two Gram-Positive Pathogens - PubMed
Thiopeptides exhibit potent antimicrobial activity against Gram-positive pathogens by inhibiting bacterial protein synthesis. Micrococcins are among the structurally simpler thiopeptides, but they have not been exploited in detail. This research involved a computational simulation of micrococcin P2 …
·pubmed.ncbi.nlm.nih.gov·
Identification of Micrococcin P2-Derivatives as Antibiotic Candidates against Two Gram-Positive Pathogens - PubMed
Understanding clinical implementation coordinators' experiences in deploying evidence-based interventions - PubMed
Understanding clinical implementation coordinators' experiences in deploying evidence-based interventions - PubMed
When implementing healthcare innovations, clinical implementation coordinators facilitated the implementation process through their roles and responsibilities and acted as strategic partners in improving the adoption and sustainability of a fluoroquinolone preauthorization protocol.
·pubmed.ncbi.nlm.nih.gov·
Understanding clinical implementation coordinators' experiences in deploying evidence-based interventions - PubMed
Empowering patients to prevent healthcare-associated infections - PubMed
Empowering patients to prevent healthcare-associated infections - PubMed
In recent years there has been increasing interest in the empowerment of patients to serve as partners in efforts to prevent healthcare-associated infections. However, patients often have limited awareness of the risk for acquisition and dissemination of healthcare-associated pathogens and have rece …
·pubmed.ncbi.nlm.nih.gov·
Empowering patients to prevent healthcare-associated infections - PubMed
Gut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field - PubMed
Gut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field - PubMed
Clostridioides difficile is an anaerobic spore-forming Gram-positive bacterium. C. difficile carriage and 16S rDNA profiling were studied in three clinical groups at three different sampling times: inflammatory bowel disease (IBD) patients, C. difficile infection (CDI) patients …
·pubmed.ncbi.nlm.nih.gov·
Gut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field - PubMed
Review of the Impact of Biofilm Formation on Recurrent Clostridioides difficile Infection - PubMed
Review of the Impact of Biofilm Formation on Recurrent Clostridioides difficile Infection - PubMed
Clostridioides difficile infection (CDI) may recur in approximately 10-30% of patients, and the risk of recurrence increases with each successive recurrence, reaching up to 65%. C. difficile can form biofilm with approximately 20% of the bacterial genome expressed differently between b …
·pubmed.ncbi.nlm.nih.gov·
Review of the Impact of Biofilm Formation on Recurrent Clostridioides difficile Infection - PubMed
Clostridioides difficile from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective - PubMed
Clostridioides difficile from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective - PubMed
Clostridioides difficile is the most important pathogen causing antimicrobial-associated diarrhea and has recently been recognized as a cause of community-associated C. difficile infection (CA-CDI). This study aimed to characterize virulence factors, antimicrobial resistance (AMR), rib …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective - PubMed
Protective Effects of Alginate and Chitosan Oligosaccharides against Clostridioides difficile Bacteria and Toxin - PubMed
Protective Effects of Alginate and Chitosan Oligosaccharides against Clostridioides difficile Bacteria and Toxin - PubMed
Clostridioides difficile infection is expected to become the most common healthcare-associated infection worldwide. C. difficile-induced pathogenicity is significantly attributed to its enterotoxin, TcdA, which primarily targets Rho-GTPases involved in regulating cytoskeletal and tight …
·pubmed.ncbi.nlm.nih.gov·
Protective Effects of Alginate and Chitosan Oligosaccharides against Clostridioides difficile Bacteria and Toxin - PubMed
The Effect of Subinhibitory Concentration of Metronidazole on the Growth and Biofilm Formation on Toxigenic Clostridioides difficile Strains Belonging to Different Ribotypes - PubMed
The Effect of Subinhibitory Concentration of Metronidazole on the Growth and Biofilm Formation on Toxigenic Clostridioides difficile Strains Belonging to Different Ribotypes - PubMed
Clostridioides difficile is a predominant nosocomial pathogen within the healthcare setting able to produce biofilms. Sub-minimum inhibitory concentrations (sub-MICs) of antibiotics trigger mechanisms affecting bacterial virulence, including increased adhesion and biofilm formation. The aim o …
·pubmed.ncbi.nlm.nih.gov·
The Effect of Subinhibitory Concentration of Metronidazole on the Growth and Biofilm Formation on Toxigenic Clostridioides difficile Strains Belonging to Different Ribotypes - PubMed
Short-Chain Fatty Acid Levels after Fecal Microbiota Transplantation in a Pediatric Cohort with Recurrent Clostridioides difficile Infection - PubMed
Short-Chain Fatty Acid Levels after Fecal Microbiota Transplantation in a Pediatric Cohort with Recurrent Clostridioides difficile Infection - PubMed
Though antibiotics are the mainstay treatment for Clostridioides difficile, a large population of individuals infected will experience recurrence. In turn, fecal microbiota transplantation (FMT) has emerged as a promising treatment for recurrent C. difficile infection (rCDI). Mechanist …
·pubmed.ncbi.nlm.nih.gov·
Short-Chain Fatty Acid Levels after Fecal Microbiota Transplantation in a Pediatric Cohort with Recurrent Clostridioides difficile Infection - PubMed
Analysis of Clostridioides difficile Infection in Children with Diarrhea in Two Hospitals in Southern Brazil - PubMed
Analysis of Clostridioides difficile Infection in Children with Diarrhea in Two Hospitals in Southern Brazil - PubMed
Clostridioides difficile infection (CDI) has been increasingly observed in children, but there is a lack of epidemiological and molecular data on CDI in Latin America. This prospective cohort study aimed to investigate the role of CDI in children with diarrhea. It included 105 children with antimicr …
·pubmed.ncbi.nlm.nih.gov·
Analysis of Clostridioides difficile Infection in Children with Diarrhea in Two Hospitals in Southern Brazil - PubMed
Look What the Cat Dragged in! Recurrent Clostridioides difficile from a Household Cat - PubMed
Look What the Cat Dragged in! Recurrent Clostridioides difficile from a Household Cat - PubMed
BACKGROUND Clostridioides difficile (C. difficile) is a bacterium that is well known for causing serious diarrheal infections and can even lead to colon cancer if left untreated. Disruption of the normal healthy bacteria in the colon can lead to development of C. difficile colitis. Risk factors for …
·pubmed.ncbi.nlm.nih.gov·
Look What the Cat Dragged in! Recurrent Clostridioides difficile from a Household Cat - PubMed
Update on potential interventions to reduce the risk for transmission of health care-associated pathogens from floors and sinks - PubMed
Update on potential interventions to reduce the risk for transmission of health care-associated pathogens from floors and sinks - PubMed
Health care facility floors and sink drains and other wastewater drainage sites are universally contaminated with potential pathogens and there are plausible mechanisms by which organisms can be disseminated from these sites. However, floors and sink drains are not addressed as potential sources of …
·pubmed.ncbi.nlm.nih.gov·
Update on potential interventions to reduce the risk for transmission of health care-associated pathogens from floors and sinks - PubMed
Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Clostridioides difficile (C. diff.) infection (CDI) is a leading cause of hospital acquired diarrhea in North America and Europe and a major cause of morbidity and mortality. Known risk factors do not fully explain CDI susceptibility, and genetic susceptibility is suggested by the fact that some pat …
·pubmed.ncbi.nlm.nih.gov·
Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection - PubMed
Effect of Clinician-Initiated C. difficile Testing on Outcomes of Patient with C. difficile Infection
Effect of Clinician-Initiated C. difficile Testing on Outcomes of Patient with C. difficile Infection
The following is a summary of “Does clinician-initiated Clostridioides difficile testing improve outcomes of patients with Clostridioides Difficile infection?” published in the October 2023 issue of Infectious Control by Bartlett, et al. Clostridioides difficile (C. difficile) is a common illness that people get in hospitals. It can have serious effects on patients and our healthcare
·news.google.com·
Effect of Clinician-Initiated C. difficile Testing on Outcomes of Patient with C. difficile Infection
PCT and HypoClean Team Up to Help Grow Veteran Commercial Cleaning, LLC
PCT and HypoClean Team Up to Help Grow Veteran Commercial Cleaning, LLC
LITTLE RIVER, SC, Oct. 30, 2023 (GLOBE NEWSWIRE) -- via NewMediaWire - PCT LTD (“PCTL” OTC Pink): Paradigm Convergence Technologies Corp (a Subsidiary of PCTL) manufactures, sells and leases equipment which produce a variety of EPA approved, eco-friendly disinfectant and degreaser fluids, is proud to announce its partnership with HypoClean, LLC a Colorado corporation specializing in hypochlorous acid (HOCl) technology and Veteran Commercial Cleaning, LCC, a global professional, commercial cleani
·news.google.com·
PCT and HypoClean Team Up to Help Grow Veteran Commercial Cleaning, LLC
Serial Fecal Microbiota Infusions via Colonoscopy for Active Ulcerative Colitis: A Feasibility, Safety, and Translational Monocentric Italian Study - PubMed
Serial Fecal Microbiota Infusions via Colonoscopy for Active Ulcerative Colitis: A Feasibility, Safety, and Translational Monocentric Italian Study - PubMed
The effectiveness of fecal microbiota transplantation (FMT) in ulcerative colitis (UC) remains unclear. This study aimed to investigate the feasibility and effectiveness of serial fecal infusions via colonoscopy in patients with active UC. Subjects with mild-to-moderate UC received three consecutive …
·pubmed.ncbi.nlm.nih.gov·
Serial Fecal Microbiota Infusions via Colonoscopy for Active Ulcerative Colitis: A Feasibility, Safety, and Translational Monocentric Italian Study - PubMed
Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection - PubMed
Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection - PubMed
These data suggest that IBD patients, potentially due to underlying intestinal dysbiosis, experience undiagnosed C. difficile infections that result in impaired toxin-specific immunity. This may contribute to the development of inflammatory T cell responses toward commensal bacteria and provide a ra …
·pubmed.ncbi.nlm.nih.gov·
Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection - PubMed