C Difficile

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Rebyota Found Safe, Effective in Preventing Recurring Clostridioides Difficile Infection
Rebyota Found Safe, Effective in Preventing Recurring Clostridioides Difficile Infection
Treatment-emergent adverse events associated with Rebyota for Clostridioides difficile infection were more prevalent in those with renal comorbidities than in those without and were moderate in severity as well as related to pre-existing conditions.
·news.google.com·
Rebyota Found Safe, Effective in Preventing Recurring Clostridioides Difficile Infection
Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review - PubMed
Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review - PubMed
Frailty and poor health status are risk factors for CDI in the elderly. CDI affects quality of life, cognition and functionality, contributing to a decline in patient health over time and leading to early and late mortality. Narrative synthesis of the evidence suggests a framework for viewing the cy …
·pubmed.ncbi.nlm.nih.gov·
Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review - PubMed
Fecal microbiota transplantation for treatment of refractory or recurrent Clostridioides difficile infection in Taiwan: a cost-effectiveness analysis - PubMed
Fecal microbiota transplantation for treatment of refractory or recurrent Clostridioides difficile infection in Taiwan: a cost-effectiveness analysis - PubMed
FMT is cost-effective, compared to vancomycin or fidaxomicin, for the treatment of rCDI in most scenarios from the payers' perspective in Taiwan.
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation for treatment of refractory or recurrent Clostridioides difficile infection in Taiwan: a cost-effectiveness analysis - PubMed
Examining the Impact of Enhanced Infection Prevention Measures on HAIs, Including CLABSIs
Examining the Impact of Enhanced Infection Prevention Measures on HAIs, Including CLABSIs
In an interview with Amy Spallone, MD, from The University of Texas MD Anderson Cancer Center, the study investigates the effects of COVID-19 precautions on healthcare-associated infections, revealing surprising results in central line-associated bloodstream infections (CLABSIs), C difficile infections, and more.
·news.google.com·
Examining the Impact of Enhanced Infection Prevention Measures on HAIs, Including CLABSIs
[Clostridioides difficile infections] - PubMed
[Clostridioides difficile infections] - PubMed
Here, we describe the epidemiology, diagnostics, and treatment of Clostridioides difficile infection (CDI) in the primary health care setting. CDI is traditionally considered as a healthcare associated infection. However, infections with onset in the community represent a large proportion of …
·pubmed.ncbi.nlm.nih.gov·
[Clostridioides difficile infections] - PubMed
The role of microbiota in the development and treatment of gastric cancer - PubMed
The role of microbiota in the development and treatment of gastric cancer - PubMed
The stomach was once considered a sterile organ until the discovery of Helicobacter pylori (HP). With the application of high-throughput sequencing technology and macrogenomics, researchers have identified fungi and fivemajor bacterial phyla within the stomachs of healthy individuals. These m …
·pubmed.ncbi.nlm.nih.gov·
The role of microbiota in the development and treatment of gastric cancer - PubMed
Modulation of gut microbiota: a novel approach to enhancing the effects of immune checkpoint inhibitors - PubMed
Modulation of gut microbiota: a novel approach to enhancing the effects of immune checkpoint inhibitors - PubMed
Although immune checkpoint inhibitors (ICIs) have greatly improved the prognosis of some cancer patients, the majority still fail to respond adequately, and the available biomarkers cannot reliably predict drug efficacy. The gut microbiota has received widespread attention among the various intrinsi …
·pubmed.ncbi.nlm.nih.gov·
Modulation of gut microbiota: a novel approach to enhancing the effects of immune checkpoint inhibitors - PubMed
Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies - PubMed
Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies - PubMed
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It's also the leading cause of liver-related hospitalizations and deaths. Furthermore, there is a link between obesity and NAFLD risk. A projected 25% of the world's population grieves from NAFLD, …
·pubmed.ncbi.nlm.nih.gov·
Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies - PubMed
Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - PubMed
Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - PubMed
Irritable bowel syndrome (IBS) poses a significant challenge due to its poorly understood pathogenesis, substantial morbidity, and often inadequate treatment outcomes. The role of fecal microbiota transplantation (FMT) in managing IBS symptoms remains inconclusive. This systematic review and meta-an …
·pubmed.ncbi.nlm.nih.gov·
Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - PubMed
Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice - PubMed
Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice - PubMed
Aim: To investigate the effect of treatment with fecal microbiota transplantation (FMT) and galacto- and fructo-oligosaccharides on ulcerative colitis (UC) in mice. Materials & methods: A total of 90 mice, divided into nine groups, were administered FMT or prebiotics or combined tr …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice - PubMed
Editorial: Continuous monitoring to improve outcome of treatment-the next step towards safe and effective faecal microbiota transplantation. Authors' reply - PubMed
Editorial: Continuous monitoring to improve outcome of treatment-the next step towards safe and effective faecal microbiota transplantation. Authors' reply - PubMed
Editorial: Continuous monitoring to improve outcome of treatment-the next step towards safe and effective faecal microbiota transplantation. Authors' reply
·pubmed.ncbi.nlm.nih.gov·
Editorial: Continuous monitoring to improve outcome of treatment-the next step towards safe and effective faecal microbiota transplantation. Authors' reply - PubMed
Murine sterile fecal filtrate is a potent pharmacological agent that exerts age-independent immunomodulatory effects in RAW264.7 macrophages - PubMed
Murine sterile fecal filtrate is a potent pharmacological agent that exerts age-independent immunomodulatory effects in RAW264.7 macrophages - PubMed
Our results indicate that SFF is a potent stimulant of macrophages and confers strong anti-inflammatory effects regardless of donor age thereby suggesting its therapeutic efficacy in lieu of FMT therapy.
·pubmed.ncbi.nlm.nih.gov·
Murine sterile fecal filtrate is a potent pharmacological agent that exerts age-independent immunomodulatory effects in RAW264.7 macrophages - PubMed
TGR5 deficiency-induced anxiety and depression-like behaviors: The role of gut microbiota dysbiosis - PubMed
TGR5 deficiency-induced anxiety and depression-like behaviors: The role of gut microbiota dysbiosis - PubMed
TGR5 deletion in mice induces anxiety and depression-like behaviors, linked to reduced 5-HT levels in serum and the hippocampus. Gut microbiota changes play a direct role in these behaviors and serotonin alterations. This implicates TGR5 and gut bacteria in mood regulation, with potential therapeuti …
·pubmed.ncbi.nlm.nih.gov·
TGR5 deficiency-induced anxiety and depression-like behaviors: The role of gut microbiota dysbiosis - PubMed
Factors Associated With Fecal Microbiota Transplant Failure in the Treatment of Recurrent Clostridioides difficile Infection: A Single-Center Retrospective Study - PubMed
Factors Associated With Fecal Microbiota Transplant Failure in the Treatment of Recurrent Clostridioides difficile Infection: A Single-Center Retrospective Study - PubMed
Background Clostridioides difficile infection (CDI) is a major cause of hospital-acquired diarrhea and is associated with substantial morbidity and mortality. Recurrences following treatment are common. Fecal microbiota transplantation (FMT) is a therapeutic intervention in which stool from a …
·pubmed.ncbi.nlm.nih.gov·
Factors Associated With Fecal Microbiota Transplant Failure in the Treatment of Recurrent Clostridioides difficile Infection: A Single-Center Retrospective Study - PubMed
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation - PubMed
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation - PubMed
FMT from HUC-MSCs-treated mice may alleviate ALI by inhibiting inflammation and reconstructing GM, additionally, we also found that the TLR4/NF-κB and Nrf2/HO-1 pathways may involve in the improvement of FMT on ALI, which offers novel insights for the functions and mechanisms of FMT from HUC-MSCs-tr …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation - PubMed
Fecal transplant ‘not over yet’ for C. difficile despite boom in live microbiota therapies
Fecal transplant ‘not over yet’ for C. difficile despite boom in live microbiota therapies
Clostridioides difficile infection presents a unique treatment paradox for clinicians: Antibiotics are often both its cause and its cure.The broad-spectrum antibiotics doled out to treat infections also radically alter the composition of the microbiota, wiping out a significant portion of the bacterial community and upsetting the natural balance of gut flora. Without competition from healthy
·news.google.com·
Fecal transplant ‘not over yet’ for C. difficile despite boom in live microbiota therapies