C Difficile

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HRMAS 13 C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile - PubMed
HRMAS 13 C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile - PubMed
Stickland-fermenting Clostridia preferentially ferment amino acids to generate energy and anabolic substrates for growth. In gut ecosystems, these species prefer dual redox substrates, particularly mucin-abundant leucine. Here, we establish how theronine, a more prevalent, mucin-abundant subs …
·pubmed.ncbi.nlm.nih.gov·
HRMAS 13 C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile - PubMed
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Clostridioides difficile (CD) is one of the most important causes of diarrhea in hospitalized patients, in particular those who undergo an allogeneic hematopoietic cell transplant (allo-HCT) and who are more at risk of developing a CD infection (CDI) due to frequent hospitalizations, iatrogenic immu …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Hepatobiliary and pancreatic: Multi-donor fecal microbiota transplantation attenuated high-fat diet-induced hepatic steatosis in mice by remodeling the gut microbiota - PubMed
Hepatobiliary and pancreatic: Multi-donor fecal microbiota transplantation attenuated high-fat diet-induced hepatic steatosis in mice by remodeling the gut microbiota - PubMed
NAFLD patients and healthy controls showed distinct gut microbiota. Likewise, HFD altered gut microbiota in mice compared to NCD-fed controls. MD-FMT restored gut dysbiosis in HFD-fed mice and attenuated liver steatosis, and should be considered as an effective treatment option for NAFLD.
·pubmed.ncbi.nlm.nih.gov·
Hepatobiliary and pancreatic: Multi-donor fecal microbiota transplantation attenuated high-fat diet-induced hepatic steatosis in mice by remodeling the gut microbiota - PubMed
Current use of fecal microbiota transfer in patients with hematologic diseases: a survey on behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT - PubMed
Current use of fecal microbiota transfer in patients with hematologic diseases: a survey on behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT - PubMed
Current use of fecal microbiota transfer in patients with hematologic diseases: a survey on behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT
·pubmed.ncbi.nlm.nih.gov·
Current use of fecal microbiota transfer in patients with hematologic diseases: a survey on behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT - PubMed
Microbial ecology between Clostridioides difficile and gut microbiota - PubMed
Microbial ecology between Clostridioides difficile and gut microbiota - PubMed
Clostridioides difficile colonizes a polymicrobial environment in the intestine and is a causative agent for antibiotic-associated diarrhea (AAD) and pseudomembranous colitis (PMC). The most important virulence factors of C. difficile are bacterial toxins, and three toxins (toxin A, to …
·pubmed.ncbi.nlm.nih.gov·
Microbial ecology between Clostridioides difficile and gut microbiota - PubMed
Thierry Racon’s Gloves
Thierry Racon’s Gloves
As part of our rapid and seemingly relentless fall through the football pyramid, nothing said it more for me than a cold night in Feb 2011 at The Valley when in front of a full ‘football for …
·alburyaddick.wordpress.com·
Thierry Racon’s Gloves
The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances - PubMed
The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances - PubMed
There are complex interactions between the gut and the brain. With increasing research on the relationship between gut microbiota and brain function, accumulated clinical and preclinical evidence suggests that gut microbiota is intimately involved in the pathogenesis of neurodegenerative diseases (N …
·pubmed.ncbi.nlm.nih.gov·
The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances - PubMed
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Clostridioides difficile (CD) is one of the most important causes of diarrhea in hospitalized patients, in particular those who undergo an allogeneic hematopoietic cell transplant (allo-HCT) and who are more at risk of developing a CD infection (CDI) due to frequent hospitalizations, iatrogenic immu …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient - PubMed
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
The established statements are summarised in the supplementary tables in the appendix to this paper. The working group hopes these will help standardise FMT practice in Switzerland and contribute to making faecal microbiota transplantation a safe and accessible treatment for patients with recurrent …
·pubmed.ncbi.nlm.nih.gov·
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
High-fat diet promotes colitis-associated tumorigenesis by altering gut microbial butyrate metabolism - PubMed
High-fat diet promotes colitis-associated tumorigenesis by altering gut microbial butyrate metabolism - PubMed
Background: Dietary fat intake is associated with an increased risk of colitis associated cancer (CAC). A high-fat diet (HFD) leads to systemic low-grade inflammation. The colon is believed to be the first organ suffering from inflammation caused by the infiltration of pro-inflammatory macrop …
·pubmed.ncbi.nlm.nih.gov·
High-fat diet promotes colitis-associated tumorigenesis by altering gut microbial butyrate metabolism - PubMed
Toward an integrative framework for microbial community coalescence - PubMed
Toward an integrative framework for microbial community coalescence - PubMed
Community coalescence is defined as the mixing of intact ecological communities. From river confluences to fecal microbiota transplantation, community coalescence constitutes a common ecological occurrence affecting natural and engineered microbial systems. In this opinion article, we propose an int …
·pubmed.ncbi.nlm.nih.gov·
Toward an integrative framework for microbial community coalescence - PubMed
Minimizing the risk of Clostridioides difficile infection as an early complication of autologous stem cell transplantation - PubMed
Minimizing the risk of Clostridioides difficile infection as an early complication of autologous stem cell transplantation - PubMed
This quality improvement project aimed to reduce institutional incidence of Clostridioides difficile infection (CDI) following autologous stem cell transplantation. CDI incidence per transplant was .17 in a baseline period and .09 following the implementation of postdischarge ultraviolet room …
·pubmed.ncbi.nlm.nih.gov·
Minimizing the risk of Clostridioides difficile infection as an early complication of autologous stem cell transplantation - PubMed
Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile - PubMed
Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile - PubMed
Clostridioides difficile, the causative agent of antibiotic-associated diarrhea and pseudomembranous colitis, has emerged as a major enteric pathogen in recent years. Antibiotic treatment perturbs the gut microbiome homeostasis, which facilitates the colonization and proliferation of the path …
·pubmed.ncbi.nlm.nih.gov·
Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile - PubMed
Outcomes of high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection - PubMed
Outcomes of high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection - PubMed
High-dose oral beta-lactams were as safe and effective as oral FQ or TMP/SMX for the treatment of bacteremia from a urinary source. Most patients received 8-10 days of therapy in both groups.
·pubmed.ncbi.nlm.nih.gov·
Outcomes of high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection - PubMed
Phage therapy in gut microbiome - PubMed
Phage therapy in gut microbiome - PubMed
Phage therapy, the use of bacteriophage viruses for bacterial infection treatment, has been around for almost a century, but with the increase in antibiotic use, its importance has declined rapidly. There has been renewed interest in revisiting this practice due to the general decline in the effecti …
·pubmed.ncbi.nlm.nih.gov·
Phage therapy in gut microbiome - PubMed
Biofilm Formation of Clostridioides difficile, Toxin Production and Alternatives to Conventional Antibiotics in the Treatment of CDI - PubMed
Biofilm Formation of Clostridioides difficile, Toxin Production and Alternatives to Conventional Antibiotics in the Treatment of CDI - PubMed
Clostridioides difficile is considered a nosocomial pathogen that flares up in patients exposed to antibiotic treatment. However, four out of ten patients diagnosed with C. difficile infection (CDI) acquired the infection from non-hospitalized individuals, many of whom have not been tr …
·pubmed.ncbi.nlm.nih.gov·
Biofilm Formation of Clostridioides difficile, Toxin Production and Alternatives to Conventional Antibiotics in the Treatment of CDI - PubMed
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
The established statements are summarised in the supplementary tables in the appendix to this paper. The working group hopes these will help standardise FMT practice in Switzerland and contribute to making faecal microbiota transplantation a safe and accessible treatment for patients with recurrent …
·pubmed.ncbi.nlm.nih.gov·
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice - PubMed
Evaluation of a mobile disinfection cabinet using ultraviolet-C light and aerosolized hydrogen peroxide for disinfection of medical equipment - PubMed
Evaluation of a mobile disinfection cabinet using ultraviolet-C light and aerosolized hydrogen peroxide for disinfection of medical equipment - PubMed
In laboratory testing, a mobile enclosed disinfection cabinet using ultraviolet-C light and aerosolized hydrogen peroxide was effective for disinfection of hard and soft surfaces. The addition of aerosolized hydrogen peroxide to ultraviolet-C light resulted in improved disinfection of soft surfaces …
·pubmed.ncbi.nlm.nih.gov·
Evaluation of a mobile disinfection cabinet using ultraviolet-C light and aerosolized hydrogen peroxide for disinfection of medical equipment - PubMed
Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach - PubMed
Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach - PubMed
Molecular mimicry, a phenomenon in which microbial or environmental antigens resemble host antigens, has been proposed as a potential trigger for autoimmune responses. In this study, we employed a bioinformatics approach to investigate the role of molecular mimicry in Clostridioides difficile …
·pubmed.ncbi.nlm.nih.gov·
Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach - PubMed