Fecal Microbiota Transplantation in Human Immunodeficiency Virus-Infected Patient Population: A Systematic Review and Meta-Analysis - PubMed
Current evidence demonstrated that FMT is safe and effective in HIV patients suffering from alterations in gut microbiota. We recommend further multi-centric clinical studies to address the optimal transplant amount and source for FMT. To the best of our knowledge, this is the first meta-analysis to …
Clostridioides difficile Infection in COVID-19 Hospitalized Patients: A Nationwide Analysis - PubMed
CDI is independently associated with increased mortality in patients admitted with COVID-19 infection. Female gender and several pre-existing comorbidities are independent predictors of CDI in COVID-19 patients.
C. difficile Infection Therapeutic Drug Market Size and Market Drivers Analysis | Growth Rate and Forecast till 2030 | with 131 Pages
Recent research on the "C. difficile Infection Therapeutic Drug Market" offers a thorough analysis of market growth prospects as well as current kinds [Metronidazole, Vancomycin, Fidaxomicin, Bezlotoxumab] and
The microbial-derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota - PubMed
Clostridioides difficile is a Gram-positive, spore-forming anaerobe that causes clinical diseases ranging from diarrhea and pseudomembranous colitis to toxic megacolon and death. C. difficile infection (CDI) is associated with antibiotic usage, which disrupts the indigenous gut microbi …
Bacillus velezensis DSM 33864 reduces Clostridioides difficile colonization without disturbing commensal gut microbiota composition - PubMed
Up to 25% of the US population harbor Clostridioides difficile in the gut. Following antibiotic disruption of the gut microbiota, C. difficile can act as an opportunistic pathogen and induce potentially lethal infections. Consequently, reducing the colonization of C. difficile in at-risk populations …
The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes: a Systematic Review and Meta-analysis - PubMed
Setting patient-relevant outcomes for CDI independently of the RCT definitions and results might lead to less confidence in the guidance for CDI management.
Three therapeutic regulatory approvals in less than a year signal that the promise of the human microbiome may finally be paying off. All of the approved therapies focus on treating recurrent Clostridium difficile infection, but what is next for the field? With promising oncology-related trial results from a number of researchers and companies such as […]
Fecal Microbiota Transplantation Market Growth (Size and Share) 2023-2031 Regional Outlook Analysis
"Final Report will add the analysis of the impact of COVID-19 on this industry."This full and thorough report, titled "Fecal Microbiota Transplantation Market" Insights of 2023, offers a thorough analysis of the market's
Gut Microbial Metabolome and Dysbiosis in Neurodegenerative Diseases: Psychobiotics and Fecal Microbiota Transplantation as a Therapeutic Approach-A Comprehensive Narrative Review - PubMed
The comprehensive narrative review conducted in this study delves into the mechanisms of communication and action at the molecular level in the human organism. The review addresses the complex mechanism involved in the microbiota-gut-brain axis as well as the implications of alterations in the micro …
Current and Emerging Applications of Fecal Microbiota Transplantation - PubMed
Fecal microbiota transplantation (FMT) is a life-changing treatment for people with recurrent Clostridioides difficile infection (rCDI). Frequently acquired in the hospital, CDI can cause serious gastrointestinal symptoms, including persistent watery diarrhea, abdominal pain, and severe dehydration. …
Pick fecal microbiota transplantation to enhance therapy for major depressive disorder - PubMed
In recent years, fecal microbiota transplantation (FMT) has emerged as a promising therapy for major depressive disorder (MDD). The goal of the operation is to restore a healthy gut microbiota by introducing feces from a healthy donor into the recipient's digestive system. The brain-gut axis is thou …
[Influence of different fecal microbiota transplantation cycles on the recovery of intestinal microbiota in the antibiotic cocktail-pretreated mice] - PubMed
Fecal bacteria transplantation helps to restore the intestinal microbiota structure of mice cleaned by antibiotics, and different transplantation frequencies and transplantation times have different recovery effects on the intestinal microbiota of mice pretreated with antibiotics, and the fecal bact …
Environmental approaches to controlling Clostridioides difficile infection in healthcare settings - PubMed
As today's most prevalent and costly healthcare-associated infection, hospital-onset Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence of C. diffici …
Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammation - PubMed
Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea, and its clinical symptoms can span from asymptomatic colonization to pseudomembranous colitis and even death. The current standard of care for CDI is antibiotic treatment to achieve bacterial clearance; …
Measuring antimicrobial use to assess your Antimicrobial Stewardship Program
Maximize your Antimicrobial Stewardship Program's impact with our guide on measuring antimicrobial use, tracking DOT, and analyzing prescribing trends.
Current and Emerging Applications of Fecal Microbiota Transplantation - PubMed
Fecal microbiota transplantation (FMT) is a life-changing treatment for people with recurrent Clostridioides difficile infection (rCDI). Frequently acquired in the hospital, CDI can cause serious gastrointestinal symptoms, including persistent watery diarrhea, abdominal pain, and severe dehydration. …
Inhibition of selenoprotein synthesis is not the mechanism by which auranofin inhibits growth of Clostridioides difficile - PubMed
Clostridioides difficile infections (CDIs) are responsible for a significant number of antibiotic-associated diarrheal cases. The standard-of-care antibiotics for C. difficile are limited to fidaxomicin and vancomycin, with the recently obsolete metronidazole recommended if both are unavailable. No …
Environmental approaches to controlling Clostridioides difficile infection in healthcare settings - PubMed
As today's most prevalent and costly healthcare-associated infection, hospital-onset Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence of C. diffici …
The long and sinuous road to phage-based therapy of Clostridioides difficile infections - PubMed
With the antibiotic crisis and the rise in antimicrobial resistance worldwide, new therapeutic alternatives are urgently needed. Phage therapy represents one of the most promising alternatives but for some pathogens, such as Clostridioides difficile, important challenges are being faced. The …
Prevalence of Clostridioides difficile contamination in the healthcare environment and instruments: A systematic review and meta-analysis - PubMed
In conclusion, hospitals' medical devices and environmental surfaces are considered a crucial source of Clostridioides difficile infection. In this regard, we strongly recommend revising and improving the cleaning and disinfection methods in hospitals and quality control of cleaning adequacy.
Targeting The Gut–Brain Axis With Live Biotherapeutic Products
Treating seizures with bacteria — Bloom Science's CEO, Dr. Christopher Reyes, explains how his company aims to leverage the gut–brain axis using live biotherapeutic products (LBP).
GI Stool Testing Market Size 2023 (New Insights Report) Competitive benchmarking, Historical data, Company revenue shares, Regional opportunities, Latest trends & dynamics Future Growth by 2030
[97 Pages Report] GI Stool Testing Market is a dynamic and multifaceted industry that warrants a comprehensive analysis. This report delves into the nuances of this market, offering a 360-degree view of its various
Washed microbiota transplantation for Clostridioides difficile infection: a national multi-center real-world study - PubMed
This study emphasizes the attractive value of WMT for CDI. Early WMT might be a recommendation for CDI, especially for those in serious condition or with complex comorbidities for decreasing deterioration, medical costs, and pain. This article is protected by copyright. All rights reserved.