C Difficile

The intestinal microbiota is the set of bacteria and viruses that live inside your gut. Microbiota perform a variety of functions, including digesting food and protecting against specific pathogens.

The resources are available on the ADA’s Oral Health Topics webpage on antibiotic stewardship.

For breast cancer patients undergoing breast reconstruction after mastectomy, avoiding postoperative oral antibiotics does not reduce the risk of infections, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.

BENNINGTON — A jury has awarded a Salem, N.Y., man $250,000 after finding medical negligence on the part of a physician who treated him in 2014 during a stay at

According to a recent Cochrane Review, stool transplantation has proven to be a more effective method of treating Clostridioides difficile infection as compared to standard antibiotic treatment. According to a recent Cochrane Review headed by a professor at Upstate Medical University, stool tran

⁦@Siew_C_Ng⁩ presenting #FMT trial in bloating with #IBS ⁦@DDWMeeting⁩ #DDW23 ⁦@ANMSociety⁩ ⁦@RomeFoundation⁩ pic.twitter.com/jI0r8iVXBM— Madhusudan (Madhu) Grover M.D., AGAF (@mgrover_gi) May 6, 2023

Lunch n learn on #Cdiff and microbiota therapies @DDWMeeting with #twitterless Dr. Byron Vaughn and super star GI fellow Dr. Lawrence Leung from Kaiser San Francisco@AmerGastroAssn pic.twitter.com/ducw1vMNib— Sahil Khanna, MBBS, MS, FACG, AGAF (he/him) (@Khanna_S) May 6, 2023

Objective: We analyze the characteristics of Clostridioides difficile (C. difficile) infection among diarrhea patients in Kunming from 2018 to 2020 and provide evidence for follow-up surveillance and prevention. Methods: A total of 388 fecal samples of diarrhea patients f …

The FDA approval could be the first ripple in a flood of therapies targeting the gut microbiome.

The researcher discusses the findings in a new study on the efficacy and safety of fecal microbiota (REBYOTA™), the first microbiota-based live biotherapeutic

C. diff is a bacterium that can cause severe diarrhea and inflammation of the large intestine. What are your risks for C. diff infection?

We report a patient with a 5-year diagnosis of akinetic-rigid Parkinson's disease under treatment with Levodopa-Carbidopa Intestinal Gel therapy throu…

Joseph Reilly, BS, PharmD, BCGP; Candace Cotto, RN; and Andrew Skinner, MD, review C. difficile infection (CDI), its risk factors, symptoms, and quality of life for the patient.

Revisiting the donor screening protocol of faecal microbiota transplantations (FMT): a systematic review

Many lines of evidence demonstrate the associations of colorectal cancer (CRC) with intestinal microbial dysbiosis. Recent reports have suggested that maintaining the homeostasis of microbiota and host might be beneficial to CRC patients, but the underlying mechanisms remain unclear. In this study, …

Proton pump inhibitors (PPIs) are the most commonly prescribed drugs for the treatment of non-erosive reflux disease (NERD), ulcers associated with non-steroidal anti-inflammatory drugs (NSAIDs), esophagitis, peptic ulcer disease (PUD), Zollinger-Ellison syndrome (ZES), gastroesophageal reflux disea …

The Gut Microbiome Conference has become a successful event for keeping healthcare professionals and scientists informed about the latest advances in human microbiome science. Now in its 4th year, this one-of-a-kind platform provides attendees the opportunity to interact with the leading authorities on gut microbiome r

If you’re curious about Fecal Microbiota Transplant (FMT), you’ll enjoy this episode where we chat with documentary filmmaker, Saffron Cassady, whose film, Designer Sh*t, shows her struggle with ulcerative colitis. After a decade of trying conventional treatments to alleviate her symptoms, Saffron documents her journey to determine if FMT could potentially help her feel better. Saffron gives us an inside look at her documentary, the steps she took to weigh the risks and potential benefits of FMT, and how she’s feeling today. We also welcome Dr. Neil Stollman, a leading gastroenterologist and microbiome expert in Oakland, California, who offers expert insight on FMT and explains what patients need to know about the scientific evidence and future potential of FMT. Check out designershitdocumentary.com to learn more about Saffron’s documentary. About the Gastro Girl Podcast In each episode, Jacqueline Gaulin, longtime patient advocate and the Founder of Gastro Girl, Inc. and GI OnDEMAND, will tackle topics that go beyond the basic mainstream coverage of GI health to educate, inform and empower patients and their caregivers. If you crave the inside scoop on the latest news, research and resources related to gastroenterology, and want it all delivered in an engaging, friendly, nonjudgmental and educational way that features leading GI experts, inspiring patients and positive vibes, this podcast is also for you. Gastro Girl, an official patient-education partner of The American College of Gastroenterology, is committed to providing actionable and evidence-based health information to help empower patients to better health. Have a question or a digestive health-related topic you'd like us to address on an upcoming episode? Are you a patient who wants to share their story? Please email us podcast@gastrogirl.com For more info: gastrogirl.com gi.org/patients giondemand.com Follow Gastro Girl Facebook https://www.facebook.com/GASTROGIRLINC Instagram https://www.instagram.com/gastrogirl_inc Twitter https://twitter.com/gastrogirl Follow ACG Facebook https://www.facebook.com/AmCollegeGastro Instagram https://www.instagram.com/amcollegega... Twitter https://twitter.com/AmCollegeGastro Follow GIOnDEMAND Facebook https://www.facebook.com/GIonDemand/ Twitter https://twitter.com/giondemand Instagram https://www.instagram.com/giondemand/ Disclaimer: The sole purpose of the Gastro Girl podcast is to provide educational and informational content. Gastro Girl, Inc., American College of Gastroenterology, The Gastro Girl Podcast, host, Jacqueline Gaulin, and any and all guests appearing on any Gastro Girl podcast episode [Collectively the Service Provider] do not provide any medical advice and the Information will not be so construed or used as medical advice. Using, accessing and/or listening to the Gastro Girl Podcast and/or providing personal or medical information to the Service Provider does not create a clinician-patient relationship between the Service Provider and you or your patients. Nothing contained in this or any Gastro Girl Podcast episode is intended to create a clinician-patient relationship, and you will not rely on anything contained in any podcast episode in diagnosing or treating yourself or anyone else. THE INFORMATION CONTAINED IN THESE PODCAST EPISODES IS PROVIDED FOR EDUCATIONAL PURPOSES ONLY AND IS NO WAY INTENDED TO DIAGNOSE, CURE OR TREAT ANY MEDICAL OR OTHER CONDITION. PLEASE CONTACT YOUR HEALTHCARE PROVIDER WITH ANY QUESTIONS RELATED TO YOUR HEALTH AND WELLBEING. If YOU ARE EXPERIENCING A HEALTH Emergency Please CALL 911

The infection causes diarrhea and inflammation of the colon, and it can be difficult to get rid of it.

Ferring Announces Publication of a Retrospective Analysis of Data Evaluating the Safety and Efficacy of REBYOTA in Open Forum Infectious Diseases.

Immune checkpoint inhibitors (ICI) are commonly used for various malignancies. A particular checkpoint inhibitor is the anti-PD-1 antibody pembrolizumab. Immune-mediated diarrhea and colitis (IMDC) is the most frequently observed immune-related adverse event (irAE) involving the gastrointestinal sys …

The obligate anaerobic, enteric pathogen Clostridioides difficile persists in the intestinal tract by forming antibiotic-resistant endospores that contribute to relapsing and recurrent infections. Despite the importance of sporulation for C. difficile pathogenesis, environmental cues and molecular m …

Resplice clinic in Hyderabad is offering FMT for autistic children on a trial basis. Wonderful staff and an admirable effort from Dr. Chandrasekhar to make a difference in the lives of children. #FMT #Autism— ScienceforASD (@ScienceforASD) May 4, 2023

REBYOTA is indicated for the prevention of recurrence of Clostridioides difficile (C. diff) infection in individuals 18 years of age and older, following antibiotic treatment for recurrent C. diff infectionAnalysis is the first to evaluate safety and efficacy of REBYOTA in a real-world population with comorbidities and risk factors with up to six months of follow upPARSIPPANY, N.J.--(BUSINESS WIRE)-..

stems throughout the United States that were contributing to the N3C database. Centers that had fewer than 500 admissions in their dataset were excluded. Patients: Patients hospitalized with COVID-19 were included. Patients were defined to have early antibiotic use if they received at least 3 calendar days of intravenous antibiotics within the first 5 days of admission. Interventions: None. Measurements and Main Results: Of 322,867 qualifying first hospitalizations, 43,089 patients received early empiric antibiotics. Antibiotic use declined across all centers in the data collection period, from March 2020 (23%) to June 2022 (9.6%). Average rates of early empiric antibiotic use (EEAU) also varied significantly between centers (deviance explained 7.33% vs 20.0%, p 0.001). Antibiotic use decreased slightly by day 2 of hospitalization and was significantly reduced by day 5. Mechanical ventilation before day 2 (odds ratio [OR] 3.57; 95% CI, 3.42–3.72), extracorporeal membrane oxygenation before day 2 (OR 2.14; 95% CI, 1.75–2.61), and early vasopressor use (OR 1.85; 95% CI, 1.78–1.93) but not region of residence was associated with EEAU. After propensity matching, EEAU was associated with an increased risk for in-hospital mortality (OR 1.27; 95% CI, 1.23–1.33), prolonged mechanical ventilation (OR 1.65; 95% CI, 1.50–1.82), late broad-spectrum antibiotic exposure (OR 3.24; 95% CI, 2.99–3.52), and late Clostridium difficile infection (OR 1.60; 95% CI, 1.37–1.87). Conclusions: Although treatment of COVID-19 patients with empiric antibiotics has declined during the pandemic, the frequency of use remains high. There is significant inter-center variation in antibiotic prescribing practices and evidence of potential harm. Our findings are hypothesis-generating and future work should prospectively compare outcomes and adverse events....

Dr Paul Feuerstadt joins Dr David Hudesmand and Dr Jordan Axelrad in a discussion about treatment approaches for C difficile infections, and the latest advances in treating recurrent infections with fecal microbiota transplantation.

Lisa Winston, MD; Ryan Miller, DO; and Neha Nanda, MD, discuss measures to reduce the spread of health care-associated Clostridioides difficile infection.

The gut microbiota is a crucial regulator of anti-tumour immunity during immune checkpoint inhibitor therapy. Several bacteria that promote an anti-tumour response to immune checkpoint inhibitors have been identified in mice1-6. Moreover, transplantation of faecal specimens from responder …