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Background Dental pulp stem cells (DPSCs) can play a prominent role in tissue regeneration. Aloe vera L. (Liliaceae) contains the polysaccharide of acemannan that was shown to be a trigger factor fo...

Background: Pressure ulcers have afflicted critically ill patients since the dawn of recorded medicine. Pressure ulcers had adverse patient outcomes. Aloe vera as a non-pharmacological modality can be used in the pressure ulcer management. Aim of the study: to investigate the effect of Aloe Vera on the healing of second degree pressure ulcers among critically ill patients. Research design: A quasi-experimental research design was used to conduct this study. Sample: 60 adult critically ill patients developed second-degree pressure ulcer. Setting: Intensive Care Units of Emergency Hospital Mansoura University. Results: There were highly statistical significant differences between study and control groups regarding pressure ulcer wound's characteristics: size, depth, edges, wound undermining presence, skin color surrounding wound, granulation tissues presence, and epithelial tissues presence (P < 0.001**) at post intervention assessment. Conclusion: Aloe vera cream is effective in management pressure ulcers as it stimulates and accelerates the healing process. It is excellent, cheaper and safer choice than current conventional therapeutic management of pressure ulcers. Therefore, it can be routinely employed in management of pressure ulcers. Recommendation: Encourage the establishment of non-pharmacological remedies using (aloe vera) in treatment of pressure ulcer wounds and other different types of wounds.

The medicinal plants are widely recommended worldwide by the traditional and modern medical practitioners for curing various diseases of patients. Aloe vera is well known for its considerable medicinal properties. Aloe is widely used in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from X-rays, lung cancer, intestinal problems, increasing High Density Lipoprotein (HDL), reducing Low Density Lipoprotein (LDL), reducing blood sugar in Diabetics, fighting against Acquired Immuno Deficiency Syndrome (AIDS), allergies and improving immune system. Aloe is used in traditional Indian medicine for constipation, colic, skin diseases, worm infestation, and infections. It is found in variety of commercial products such as, pills, sprays, ointments, lotions, liquids, drinks, jellies and creams. All these uses associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. The chemistry of the plant has revealed that there are more than 200 different biologically active substances.

Reproductive problems such as impaired folliculogenesis and anovulation are observed in diabetic women. ...

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Background: Stomatitis is the most common complication of chemotherapy. This study aimed to assess the effect of aloe vera solution on stomatitis and its pain intensity in patients undergoing chemotherapeutic procedures.Methods: In this randomized controlled clinical trial, 64 patients with Acute Myeloid Leukemia and Acute Lymphocytic Leukemia undergoing chemotherapy were randomly divided into a control and an intervention group. The intervention group patients were asked to wash their mouths with 5 ml of aloe vera solution for two minutes three times a day for 14 days. The control group patients, however, used only the ordinary mouthwashes recommended in hematologic centers. The patients’ mouths were examined by two assistants on days 1, 3, 5, 7, and 14. The intensity of stomatitis was recorded according to WHO stomatitis intensity checklists and pain was evaluated using Visual Analog Scale. The data were analyzed by SPSS statistical software, version 18.Results: The results showed that aloe vera solution mouthwash significantly reduced the intensity of stomatitis and its pain in the intervention group compared to the control group. On the first day, no significant difference was found between the two groups regarding the mean intensity of stomatitis (P=0.178) and pain (P=0.154). However, a significant difference was observed between the two groups in this regard on other days (days 3-14: P=0.001 for stomatitis intensity, P=0.001 for pain).Conclusions: Aloe vera solution can improve the patients’ nutritional status, reduce stomatitis and its pain intensity, and increase the patients’ satisfaction.Trial Registration Number: IRCT2014092819318N1

Alzheimer's disease (AD) is a leading killer of Americans, imparts a significant toll on the quality of life of the patient and primary caregiver, and results in inordinate costs in an already overburdened medical system. Prior studies on cholinesterase inhibitors among AD patients have shown minima …

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Neurogenesis, growing new brain cells, is happening in your brain right now, and we can actually enhance this process by making smart lifestyle choices.

• Aloe's prebiotic effects are fantastic due to the chemical structure of some of its components. Surprisingly the aloe vera gel is about 55% polysaccharides and contains a compound called acemannan.

The present single-dose study was performed to assess the effect of whole coffee fruit concentrate powder (WCFC), green coffee caffeine powder (N677), grape seed extract powder (N31) and green coffee bean extract powder (N625) on blood levels of brain-derived neurotrophic factor (BDNF). Randomly ass …

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Aloe vera is compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of aloe vera treatment in r…

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Around 1750 BC Hannibal waged war to control the areas in North Africa where aloe vera flourished. It's no wonder when you understand the powerful medicine contained in this plant

Recurrent aphthous stomatitis (RAS) is the most common disorder in the oral mucosa that affects the daily quality of life of patients, and there is currently no specific treatment. In the present study, we developed aloe vera fermentation gel under the action of probiotics on aloe vera. In total, 35 patients with the history of aphthous stomatitis were enrolled to explore the potential benefits of aloe vera fermentation gel to treat RAS, and the healing-promotion effects were recorded and compared; microbial compositions in different groups were tested by high-throughput sequencing. Our results indicated that the duration of healing time of the aloe group showed potentially better effects because of the higher proportion of 4&#x2013;6 day healing time (35&#x0025; vs. 20&#x0025;) and lower proportion of 7&#x2013;10 day healing time (65&#x0025; vs. 80&#x0025;) compared with that of the chitosan group. Also, the use of aloe vera fermentation gel could return oral bacteria to normal levels and reduce the abundance of harmful oral bacteria including Actinomyces, Granulicatella, and Peptostreptococcus. These results suggest that aloe vera fermentation gel has the ability to treat patients with RAS and has positive prospects in clinical applications.

Clinicians and wound care nurses in Indonesia usually use Nigella sativa oil (NSO) gel and aloe vera (AV) gel to treat diabetic ulcers. However, there are no st...