Physicochemical Characterization of a Liposomal Formulation Based on Glucosamine and Vitamin D Commercialized as a Nutritional Supplement
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EBSCOhost 119916956 Cytotoxicity of Fucoidan from Three Tropical Bro (...)
EBSCOhost 119916956 Cytotoxicity of Fucoidan from Three Tropical Brown Algae Against Breast and Colon Cancer Cell Lines-
EBSCOhost 141060025 Determination of fucoidan in rat plasma by HPLC and its application in pharmacokinetics.
Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms
Seaweed Compound Fights Cancer NaturalHealth365
(NaturalHealth365) Did you know that seaweed offers many health benefits? Discover how this superfood helps prevent cancer.
Aloe Vera Fraud Don't Get Scammed
De novo sequencing, assembly and characterisation of Aloe vera transcriptome and analysis of expression profiles of genes related to saponin and anthraquinone metabolism BMC Genomics Full Text
Background Aloe vera is a perennial, succulent, drought-resistant plant that exhibits many pharmacological characteristics such as wound healing ability against skin burns, anti-ulcer, anti-inflammatory, anti-tumor, anti-viral, anti-hypercholesterolemic, anti-hyperglycemic, anti-asthmatic and much more. Despite great medicinal worth, little genomic information is available on Aloe vera. This study is an initiative to explore the full-scale functional genomics of Aloe vera by generating whole transcriptome sequence database, using Illumina HiSeq technology and its progressive annotation specifically with respect to the metabolic specificity of the plant. Results Transcriptome sequencing of root and leaf tissue of Aloe vera was performed using Illumina paired-end sequencing technology. De novo assembly of high quality paired-end reads, resulted into 1,61,733 and 2,21,792 transcripts with mean length of 709 and 714 nucleotides for root and leaf respectively. The non-redundant transcripts were clustered using CD-HIT-EST, yielding a total of 1,13,063 and 1,41,310 unigenes for root and leaf respectively. A total of 6114 and 6527 CDS for root and leaf tissue were enriched into 24 different biological pathway categories using KEGG pathway database. DGE profile prepared by calculating FPKM values was analyzed for differential expression of specific gene encoding enzymes involved in secondary metabolite biosynthesis. Sixteen putative genes related to saponin, lignin, anthraquinone, and carotenoid biosynthesis were selected for quantitative expression by real-time PCR. DGE as well as qRT PCR expression analysis represented up-regulation of secondary metabolic genes in root as compared to leaf. Furthermore maximum number of genes was found to be up-regulated after the induction of methyl jasmonate, which stipulates the association of secondary metabolite synthesis with the plant’s defense mechanism during stress. Various transcription factors including bHLH, NAC, MYB were identified by searching predicted CDS against PlantTFdb. Conclusions This is the first transcriptome database of Aloe vera and can be potentially utilized to characterize the genes involved in the biosynthesis of important secondary metabolites, metabolic regulation, signal transduction mechanism, understanding function of a particular gene in the biology and physiology of plant of this species as well as other species of Aloe genus.
EBSCOhost 120217311 The preventive effect of Rutin, Pine bark, Aloe (...)
EBSCOhost 120217311 The preventive effect of Rutin, Pine bark, Aloe Vera and Celery on oxidative stress factors and movement activity in focal cerebral ischemia model in rats-
EBSCOhost 126753408 Traditional tribal medicines Aloe-vera used as a (...)
EBSCOhost 127250812 Role Of Topical Aloe Vera Gel In Recovery Of Hig (...)
EBSCOhost 128497103 Aloe vera L. as Green Corrosion Inhibitor for Mi (...)
Effect of Aloe Vera Alcoholic Extract Gel on Changes of Estrogen and Progesterone in Experimental Model Rats with MS
Evaluating the Effects of Aloe vera Gel on Cerebellum Histomorphometrical Changes in Diabetic Male Rats
In vitro antimicrobial activity of Aloe vera L. extracts against patho (...)
The Plaque Inhibitory Effect of Aloe Vera Mouthrinse in A Four Day De (...)
Acacia SupergumTM Gum Arabic in vivo and in vitro Evaluation of Potential Health Benefits in Renal Disease
EBSCOhost 151826663 Some Physiological Effect of Acacia Gum on Acute Renal Failure Induced by Gentamicin in Male Rabbits.
Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial
Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial
Physicochemical Studies on Acacia Senegal Gum and Their Effect on Uric Acid Levels in Gout Patients
UKnowledge - International Grassland Congress Proceedings Performance of emAcacia senegalem L. Untapped Wealth of Gum Arabic in Rangelands and Grasslands in Arid and Semi-Arid Region of India
Acacia senegal (Linn) Wild a member of Mimosaceae is a small tree of 3-6m in height with umbrella-shaped crown. It is a typical tree of Sahel in Africa from Senegal to red sea and essentially limited to the area between 110 and 160 North, with a wide range of rainfall 100 to 800mm. It spread widely in tropical Africa from Mozambique, Zambia to Somalia, Sudan, Ethiopia, Kenya, Tanzania and Nigeria, and in South Asia in India and Pakistan. In India it is a typical tree of arid regions with a low rainfall of 100-250mm. It is drought resistant and tolerates prolonged dry period of 10-11 months, with maximum temperature reaching 500C with strong winds, but susceptible to frost. It occurs mostly on sand stones and skeletal soils and widely distributed as interspersed species in most of the rangelands and grasslands in arid and semi-arid regions of India. World’s 90% gum Arabic is produced from Acacia senegal. The quality of gum is very superior as compared to gum from any other species of Acacia (Andreson, 1990). Nearly 90% of gum Arabic is produced by Republic of Sudan especially from (Kordafan). Production of gum Arabic is meagre in India, and contribution to the world production is negligible. The total annual output of gum Arabic is only 800 Mt compared to world production and consumption of 60,000-70,000 Mt. The domestic production is insufficient even for domestic consumption and more of it is imported from Sudan and Nigeria to meet India's requirements. Gum exudes from cracks in bark of trees, mostly in the dry season. In Sudan the annual yields from young trees ranges from 188 to 2856 g (av. 0.9 kg), and from older trees, 379 to 6754 g (av. 2.0 kg). In India, however, the productivity is low varying from 175 to 550g tree-1 year-1. The main gum producing regions of India where natural as well as planted stands of A. senegal occur are in desert and arid region of Rajasthan, Gujarat, Haryana, and Punjab. The gum yield from various Acacia trees in their natural habitat is very poor. In arid and semi-arid region of India, particularly in Rajasthan, Gujarat, Haryana, Punjab and Bundelkahand, there is a good scope for extending area for large- scale plantation for production of gum Arabic. The area covered under forest, barren and uncultivable, pasture, oren (temple lands) and community grazing land etc, can be used for
An open-label dosing study to evaluate the safety and effects of a dietary plant-derived polysaccharide supplement on the N- glycosylation status of serum glycoproteins in healthy subjects
European Journal of Clinical Nutrition - An open-label dosing study to evaluate the safety and effects of a dietary plant-derived polysaccharide supplement on the N-glycosylation status of serum...
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Why Sugars Matter in Fighting Disease - A Panel Discussion - YouTube
On Nov. 1, 2018, GlycoNet held a panel discussion, Why Sugars Matter in Fighting Disease, at the Li Ka Shing Centre for Health Research Innovation in Edmonton, Alberta. The panel discussion was MC'd by author and former Daily Planet host Jay Ingram. Panel members included: Dr. Mona Nemer, Canada’s Chief Science Advisor; Dr. Todd Lowary, Scientific Director, GlycoNet; Dr. Lori West, Professor, University of Alberta and Director, Canadian Donation and Transplant Research Program (CNTRP); Dr. David Vocadlo, Professor, Simon Fraser University; Dr. Karla Williams, Assistant Professor, University of British Columbia and Co-founder of GlyCa BioSciences and; Ms. Erum Razvi, PhD candidate, The Hospital for Sick Children.
The auxiliary effects of low-molecular-weight fucoidan on the quality of life for locally advanced rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy before surgery
Background Patients with cancer use low-molecular-weight fucoidan (LMF) as a supplement to therapy. However, most studies of LMF are in vitro or conducted using animals. Concurrent chemoradiotherapy (CCRT) is the gold standard for locally advanced rectal cancer (LARC). This s...
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Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis the MICROCODE study SpringerLink
Angiogenesis - Although coronavirus disease 2019 (COVID-19) and bacterial sepsis are distinct conditions, both are known to trigger endothelial dysfunction with corresponding microcirculatory...
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis the MICROCODE study - GlycoCheck
Abstract Aims Although coronavirus disease 2019 (COVID-19) and bacterial sepsis are distinct conditions, both are known to trigger endothelial dysfunction with corresponding microcirculatory impairment. The purpose […]
P115 Trehalose modulates Dextran Sulfate Sodium-induced colitis by regulating macrophage polarization Journal of Crohn's and Colitis Oxford Academic
AbstractBackground. Inflammatory bowel disease (IBD) is a collective term for chronic inflammatory diseases resulting from complex genetic susceptibility, micro