Beyond Terrible - An Age of Mayhem, Madness, and Monsters
I should have titled this essay the worst story ever told, so fasten your seatbelts because things will only worsen from here. I am afraid that there will be little to no good news from this point forward. Evil is conquering the world, and they have us exactly where they want us. There are no... View Article
Our life and health depend on having enough CO2 in the blood and tissues. Carbon dioxide is both an essential a nutrient and a product of respiration. Its lack or deficiency is a starting point for disturbances in the body up to and including cancer. The last thing a person wants is to be bicarbonate... View Article
Network Pharmacology-Based Study on the Mechanism of Aloe Vera for Treating Cancer
Background. Aloe vera has long been considered an anticancer herb in different parts of the world. Objective. To explore the potential mechanism of aloe vera in the treatment of cancer using network pharmacology and molecule docking approaches. Methods. The active ingredients and corresponding protein targets of aloe vera were identified from the TCMSP database. Targets related to cancer were obtained from GeneCards and OMIM databases. The anticancer targets of aloe vera were obtained by intersecting the drug targets with the disease targets, and the process was presented in the form of a Venn plot. These targets were uploaded to the String database for protein-protein interaction (PPI) analysis, and the result was visualized by Cytoscape software. Go and KEGG enrichment were used to analyze the biological process of the target proteins. Molecular docking was used to verify the relationship between the active ingredients of aloe vera and predicted targets. Results. By screening and analyzing, 8 active ingredients and 174 anticancer targets of aloe vera were obtained. The active ingredient-anticancer target network constructed by Cytoscape software indicated that quercetin, arachidonic acid, aloe-emodin, and beta-carotene, which have more than 4 gene targets, may play crucial roles. In the PPI network, AKT1, TP53, and VEGFA have the top 3 highest values. The anticancer targets of aloe vera were mainly involved in pathways in cancer, prostate cancer, bladder cancer, pancreatic cancer, and non-small-cell lung cancer and the TNF signaling pathway. The results of molecular docking suggested that the binding ability between TP53 and quercetin was the strongest. Conclusion. This study revealed the active ingredients of aloe vera and the potential mechanism underlying its anticancer effect based on network pharmacology and provided ideas for further research.
Learn the Truth. This fearless lineup of guests gets straight to the point and breaks down the facts and science to expose that this entire pandemic was built on: LIES. It’s unbelievable how much of what’s really going on with the jab, shutdowns and alternate treatments are being hidden from us. This information isn’t just exclusive, it’s basically impossible to find it in today's world of censorship. That’s why it’s so important to have access to this critical information before it’s taken down… Covid Revealed
Abstract 10712 Mrna COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test a Warning Circulation
Our group has been using the PLUS Cardiac Test (GD Biosciences, Inc, Irvine, CA) a clinically validated measurement of multiple protein biomarkers which generates a score predicting the 5 yr risk (pe
Gluten and Grain Free Foods that are low in Histamine - YouTube
Think you might be gluten sensitive? Take the quiz:
https://www.glutenfreesociety.org/gluten-sensitivity-intolerance-self-test/
Hist Assist - http://glutenfreesociety.org/HistAssist
While no food is guaranteed to be entirely free from histamine, there are a number of healthy gluten-free foods that are low in histamine. These include the following:
- fresh meat and fish
- fresh and non-citrus fruits
- eggs
- dairy substitutes, such as coconut milk and almond milk (choose full fat options with minimal ingredients and no additives)
- fresh vegetables except tomatoes, avocados, spinach, and eggplant
- Coconut and olive oil
It’s important to note, however, that histamine increases as food ages. As a result, precooked and leftover foods have higher histamine levels than their fresh counterparts.
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*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world’s leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527
Neuroprotective and Proneurogenic Effects of Glucosamine in an Internal Carotid Artery Occlusion Model of Ischemia SpringerLink
NeuroMolecular Medicine - Neuroprotective, antineuroinflammatory, and proneurogenic effects of glucosamine, a naturally occurring amino sugar, have been reported in various animal models of brain...
Low Molecular Weight Fucoidan Can Inhibit the Fibrosis of Diabetic Kidneys by Regulating the Kidney Lipid Metabolism
In this study, a diabetic kidney disease model was established by placing the test rats on a high-sugar/high-fat diet combined with streptozotocin induction. Histopathological examination (H&E, Masson, and PASM stain) showed pathological changes in the diabetic rat kidneys, in addition to fibrotic symptoms and collagen deposition. Immunohistochemistry and western blot analyses indicated that the diabetic condition significantly increased the expressions of fibrotic markers including collagen, α-SMA, and fibronectin. The levels of cholesterol, triglyceride, and low-density lipoprotein were also increased in diabetic kidney disease (DKD) rat blood, while the level of high-density lipoprotein was decreased. The results of Oil red O staining experiments indicated that the kidneys of diabetic rats exhibited appreciable fat deposition, with high contents of triglyceride and cholesterol. To inhibit fibrosis and reduce fat deposition, low molecular weight fucoidan (LMWF) may be used. Based on PCR and western blot analyses, LMWF can regulate the expression levels of important lipid metabolism regulators, thereby impeding the development of kidney fibrosis. Through the vitro model, it also be indicated that LMWF could inhibit fibrosis process through regulating lipid metabolism which induced by palmitic acid.
Cureus Starvation Ketoacidosis Induced by Ketogenic Diet and Consumption of Ketone Supplement
The ever-changing landscape of dieting and its correlation with health outcomes have continued to evolve with time. New diets appear and disappear just as quickly as they gain notoriety. This is...
Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice eLife
Ketogenic diet protects against coronavirus-infected aged mice, which, like humans, are significantly more susceptible to infections, by deactivating NLRP3 inflammasome, reducing pathogenic monotypes, and expanding γδ T cells in the lung.
Peptides Prospects for Use in the Treatment of COVID-19
There is a vast practice of using antimalarial drugs, RAS inhibitors, serine protease inhibitors, inhibitors of the RNA-dependent RNA polymerase of the virus and immunosuppressants for the treatment of the severe form of COVID-19, which often occurs in ...
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Free Training Modules Peptide Therapy: Foundations Module 1 This essential virtual course on the foundations of Peptide Therapy goes over the basics of cellular medicine: how to control senescence and how to restore cellular efficiency using the signaling pathways of peptides. Take a deep dive into the TOP 11 foundational peptides that will bring improved … Free Video Courses Read More »