2016

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A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways
A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways
Fucoidan and deep-sea water (DSW) are attractive marine resources for treating type 2 diabetes (T2DM). In this study, the regulation and mechanism associated with the co-administration of the two were first studied using T2DM rats, induced by a high fat diet (HFD) and streptozocin (STZ) injection. Results demonstrate that, compared to those with DSW or FPS alone, the orally administered combination of DSW and FPS (CDF), especially the high dose (H-CDF), could preferably inhibit weight loss, decrease levels of fasting blood glucose (FBG) and lipids, and improve hepatopancreatic pathology and the abnormal Akt/GSK-3β signaling pathway. The fecal metabolomics data show that H-CDF could regulate the abnormal levels of metabolites mainly through the regulation of linoleic acid (LA) metabolism, bile acid (BA) metabolism, and other related pathways. Moreover, H-CDF could adjust the diversity and richness of bacterial flora and enrich bacterial groups, such as Lactobacillaceae and Ruminococcaceae UCG-014. In addition, Spearman correlation analysis illustrated that the interaction between the gut microbiota and BAs plays an essential role in the action of H-CDF. In the ileum, H-CDF was verified to inhibit activation of the farnesoid X receptor (FXR)–fibroblast growth factor 15 (FGF15) pathway, which is regulated by the microbiota–BA–axis. In conclusion, H-CDF enriched Lactobacillaceae and Ruminococcaceae UCG-014, thereby changing BA metabolism, linoleic acid metabolism, and other related pathways, as well as enhancing insulin sensitivity and improving glucose and lipid metabolism.
·mdpi.com·
A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways
#1 Sign That You Overdosed on Vitamin D - YouTube
#1 Sign That You Overdosed on Vitamin D - YouTube
Learn more about vitamin D toxicity and the top signs of vitamin D overdose. DATA: https://www.bmj.com/content/366/bmj.l4673.long https://www.frontiersin.org/articles/10.3389/fimmu.2022.790444/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971338/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535888/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535888/ https://iopscience.iop.org/article/10.1088/1742-6596/1073/4/042034/pdf https://vitamindwiki.com/Overview+Toxicity+of+vitamin+D https://vitamindwiki.com/tiki-index.php?page_id=2489 Watch my Other Videos on Vitamin D: How Much Vitamin D Do I Need? ▶️ https://youtu.be/NFxQJmvgXOQ Is it Safe to Take 10,000 IUs of Vitamin D3? ▶️ https://youtu.be/gjJdzHIwDDU The 7 Warning Signs of a Vitamin D Deficiency ▶️ https://youtu.be/nk4DAjtcviI 0:00 Introduction: Vitamin D overdose 0:10 Vitamin D toxicity 3:40 The #1 sign of vitamin D overdose 4:02 Other signs of too much vitamin D 4:40 Vitamin D2 vs. vitamin D3 6:25 Learn more about calcification! Today we’re going to talk about vitamin D toxicity and the signs you’re taking too much vitamin D. It’s important to keep in mind that the dangers of vitamin D deficiency outweigh the dangers of getting too much vitamin D. It’s also very difficult to overdose on vitamin D. Vitamin D works with other factors that support its function and absorption. Certain amounts of vitamin D can potentially have side effects but can be made safe by adjusting the cofactors. Magnesium and vitamin K2 are the main cofactors that help keep higher levels of vitamin D from becoming toxic. It’s also important to drink plenty of water. The side effects of vitamin D toxicity typically start to occur when a person is consuming hundreds of thousands of international units (IU) of vitamin D for many weeks. The #1 sign of vitamin D overdose: • Calcification Other signs of vitamin D overdose: • Kidney stones • Nerve symptoms (numbness, pain, or tingling) • Excessive thirst • Excessive urination In my opinion, it seems that many cases of vitamin D toxicity occur because of a person consuming too much vitamin D2—not vitamin D3. There are some big differences between vitamin D2 and vitamin D3. I also don’t think people will see the same benefits after taking vitamin D2 that they would if they took vitamin D3. A few things you need to know about vitamin D2: • It’s not as effective as D3 • It’s not as bioavailable as D3 • It’s not as studied as D3 • It doesn’t help prevent fractures like D3 can • It does help reverse rickets (in infants) • It has a different effect on depression than D3 • It doesn’t affect the immune system like D3 can Dr. Eric Berg DC Bio: Dr. Berg, age 57, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media. Follow Me On Social Media: Facebook: https://bit.ly/FB-DrBerg Instagram: https://bit.ly/IG-DrBerg Anchor: https://bit.ly/Anchor-DrBerg TikTok: https://bit.ly/TikTok-DrBerg Send a Message to his team: https://m.me/DrEricBerg Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. #keto #ketodiet #weightloss #ketolifestyle Thanks for watching! I hope this helps explain the signs of vitamin D overdose. I’ll see you in the next video.
·youtube.com·
#1 Sign That You Overdosed on Vitamin D - YouTube
The Truth About Mold in the Home - with Michael Rubino | The Empowering Neurologist EP. 160 - YouTube
The Truth About Mold in the Home - with Michael Rubino | The Empowering Neurologist EP. 160 - YouTube
As many of you may know, we live in Southwest Florida. And yes, we did experience the devastating effects of the recent hurricane. One of the things that has become an important focus of attention for many people living in this area has been remediating their homes as it relates to the possibility or even the presence of mold. That said, I recently purchased a book,The Mold Medic, by Michael Rubino, to learn more about the whole notion of mold remediation, testing, and many more issues related to this challenging situation. Let me tell you a little bit more about Michael Rubino. He is an air quality expert and wellness advocate. He is the founder and CEO of HomeCleanse which address is the worldwide health epidemic caused by poor indoor air quality. He has been in collaboration with over 100 doctors globally and his mission focuses on raising awareness and providing solutions to indoor air pollution, most specifically dealing with mold. His book, The Mold Medic: An Experts Guide on Mold Removal, is fascinating. You can also learn more about his work on his YouTube series, Mold Talks. This is a fascinating interview today where we talk about the various types of molds that can colonize our homes, how remediation should take place, how we test our homes in terms of making sure they are mold free, how insurance factors in when we've had water exposure, Michael's new nonprofit organization to allow mold remediation for underprivileged individuals, and, how we ultimately select a mold company if we indeed need remediation. ==== TIMESTAMPS: 0:00 Intro 3:56 Post-Hurricane Mold 8:37 Mold in the Bathroom 12:10 Evolution of Mold 14:59 UV, Ionizing and Filtration Systems 18:28 Checking for Mold 24:12 Mold Removal 34:25 Change The Air Foundation 38:31 Michael’s YouTube Channel 39:52 DIY Mold Testing 42:01 Conclusion ==== MICHAEL RUBINO is an air quality expert and wellness advocate, helping to bridge the gap between our homes and their direct impact on health. He is the founder and CEO of HomeCleanse (formerly known as All American Restoration), a company dedicated to addressing the worldwide health epidemic caused by poor indoor air quality. He works closely with the company's advisory team, which includes global well-being trailblazers Deepak Chopra’s The Chopra Foundation and Gwyneth Paltrow, to achieve the company's mission to improve the quality of life for 100 million people each year by 2030. Rubino is also the founder of Change the Air Foundation, a nonprofit committed to empowering the world to achieve better health by establishing safer and healthier indoor environments. Through collaboration with over 100 doctors globally, Rubino strives to not only raise awareness globally but also provide solutions to correctly identify and remove the pollutants causing this worldwide health crisis. Rubino specializes in working with people who are immunocompromised or have acute and sustained reactions to mold exposure and has helped heal over 1,000 families so far—including celebrities and athletes. He is a council-certified Mold Remediation Supervisor by ACACa nd IICRC and is a contributing member, sponsor, and speaker for the Indoor Air Quality Association. In an effort to share his expert knowledge, Rubino has authored the book, The Mold Medic: An Expert’s Guide on Mold Removal., and is an ongoing contributor to MindBodyGreen. He has been featured on Gwyneth Paltrow’s The goop Podcast, LIVESTRONG, Dr. Will Cole's The Art of Being Well Podcast, Forbes, MarketWatch, and USA Today. Rubino has appeared on television as a featured expert, including local NBC, Fox, and ABC affiliates, to name a few. To further create a worldwide community, Rubino also hosts the YouTube series, Mold Talks, where special guests include medical experts as well as mold recovery patients, including media icon Atoosa Rubenstein. Connect with Michael Rubino on Facebook @HomeCleanseCo, Instagram @TheMichaelRubino and TikTok @HomeCleanse, and visit www.homecleanse.com. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
·youtube.com·
The Truth About Mold in the Home - with Michael Rubino | The Empowering Neurologist EP. 160 - YouTube
Risk Of Ischaemic Stroke Among New Users Of Glucosamine And Chondroitin Sulphate: A Nested Case-Control Study. - Osteoarthritis and Cartilage
Risk Of Ischaemic Stroke Among New Users Of Glucosamine And Chondroitin Sulphate: A Nested Case-Control Study. - Osteoarthritis and Cartilage
Purpose: SYSADOAs (symptomatic slow-acting drugs for osteoarthritis) are a heterogeneous group of drugs that have the ability to modify the symptoms of osteoarthritis (OA) slowly and independently of NSAIDs, analgesics or any other therapeutic option. The main drugs included in this group are glucosamine (sulphate or hydrochloride) (GS) and chondroitin sulphate (CS), widely prescribed for the treatment of OA in some countries. Although the efficacy of GS and CS for the treatment of OA remains controversial, several human, animal and laboratory studies have suggested that both drugs show anti-inflammatory properties that could reduce the risk of several diseases.
·oarsijournal.com·
Risk Of Ischaemic Stroke Among New Users Of Glucosamine And Chondroitin Sulphate: A Nested Case-Control Study. - Osteoarthritis and Cartilage
Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled study - Osteoarthritis and Cartilage
Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled study - Osteoarthritis and Cartilage
To evaluate the efficacy and safety of chondroitin sulfate and/or glucosamine hydrochloride in alleviating symptoms and improving the dysfunction of Kashin-Beck disease (KBD) patients.
·oarsijournal.com·
Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled study - Osteoarthritis and Cartilage
The potential therapeutic impacts of trehalose on cardiovascular diseases as the environmental-influenced disorders: An overview of contemporary findings - ScienceDirect
The potential therapeutic impacts of trehalose on cardiovascular diseases as the environmental-influenced disorders: An overview of contemporary findings - ScienceDirect
Cardiovascular diseases (CVDs) as environmental-influenced disorders, are a major concern and the leading cause of death worldwide. A range of therape…
·sciencedirect.com·
The potential therapeutic impacts of trehalose on cardiovascular diseases as the environmental-influenced disorders: An overview of contemporary findings - ScienceDirect
Vitamin D and Dementia Risk - David Perlmutter M.D.
Vitamin D and Dementia Risk - David Perlmutter M.D.
For years I’ve been writing about the important role of vitamin D as it relates to general health and brain health in specific. And with good reason. The medical research …
·drperlmutter.com·
Vitamin D and Dementia Risk - David Perlmutter M.D.
Nutrients | Free Full-Text | Dietary Trehalose as a Bioactive Nutrient
Nutrients | Free Full-Text | Dietary Trehalose as a Bioactive Nutrient
Trehalose is a naturally occurring, non-reducing disaccharide comprising two covalently-linked glucose molecules. It possesses unique physiochemical properties, which account for multiple biological roles in a variety of prokaryotic and eukaryotic organisms. In the past few decades, intensive research on trehalose has uncovered its functions, and extended its uses as a sweetener and stabilizer in the food, medical, pharmaceutical, and cosmetic industries. Further, increased dietary trehalose consumption has sparked research on how trehalose affects the gut microbiome. In addition to its role as a dietary sugar, trehalose has gained attention for its ability to modulate glucose homeostasis, and potentially as a therapeutic agent for diabetes. This review discusses the bioactive effects of dietary trehalose, highlighting its promise in future industrial and scientific contributions.
·mdpi.com·
Nutrients | Free Full-Text | Dietary Trehalose as a Bioactive Nutrient
EP01 non-invasive Blood Glucose Monitoring Smartwatch | HRV ECG/EKG HR BP SPO2 temp Health Tracker - YouTube
EP01 non-invasive Blood Glucose Monitoring Smartwatch | HRV ECG/EKG HR BP SPO2 temp Health Tracker - YouTube
Check it out on AliExpress: https://s.click.aliexpress.com/e/_Ddxdwyr and be sure to come visit me at: https://www.DaveTheKayaker.com Also check out this blood glucose watch. So far I like it the most: https://youtu.be/4PzzQwqsWQw Subscribe and check out my "Fitness Tracker and Smartwatch Reviews" Playlist on YT. I like to bring you smartwatches that are new or different in some way, and this is the first one I've found with non-invasive blood glucose monitoring. #AliExpress #Smartwatch
·youtube.com·
EP01 non-invasive Blood Glucose Monitoring Smartwatch | HRV ECG/EKG HR BP SPO2 temp Health Tracker - YouTube
The Danger of Seed Oils & Finding a Healthier Option - w/ Jeff Nobbs | Empowering Neurologist EP159 - YouTube
The Danger of Seed Oils & Finding a Healthier Option - w/ Jeff Nobbs | Empowering Neurologist EP159 - YouTube
We've had so many discussions that's far about the importance of dietary fat for health and longevity. But to be clear, the type of fat we consume is of incredible importance. These days our diets seem to be loaded with vegetable oils and seed oils, and as we will learn, these are generally quite threatening to our health. In fact vegetable oils are only recently introduced into human nutrition with global production increasing 1600% since the early 1900s. There is a strong correlation between the increase consumption of vegetable oils and seed the oils with the incidence of severe chronic diseases including cardiovascular disease, diabetes and even various neurological conditions.  Today we are going to explore a new type of oil called cultured oil, prepared by fermentation and subsequent filtration. Leading this industry is a company called Zero Acres Farms, and as such, I have reach doubt to its co-founder and CEO, Jeff Nobbs, to explore exactly what this company is doing as well as the health benefits of their product. ==== TIMESTAMPS: 0:00 Intro 2:28 Realizing the Danger of Omega 6 10:10 Low Fat Diets 12:35 HNE 17:00 Inflammation & Lanolin Acid 20:38 Environmental Impact of Seed Oils 24:00 Saturated Fat 28:15 New Way to Produce Oils 33:36 What to Look for while buying 39:02 Conclusion ==== Jeff Nobbs: Jeff Nobbs is the co-founder and CEO of Zero Acre Farms, a food company replacing destructive vegetable oils with healthier, more sustainable oils and fats made by fermentation. Prior to Zero Acre Farms, Jeff also co-founded the fast casual restaurant chain Kitava, food security non-profit HelpKitchen, and rewards shopping platform Extrabux. He has also served as COO for Perfect Keto and General Manager of Rakuten after it acquired Extrabux. Jeff blogs about health, nutrition, and sustainability at jeffnobbs.com ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
·youtube.com·
The Danger of Seed Oils & Finding a Healthier Option - w/ Jeff Nobbs | Empowering Neurologist EP159 - YouTube