Crystal structure of rare sugars
2016
Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique
Comprehensive analysis of the lipid content in Cordyceps sinensis samples is essential for optimizing their effective use. Understanding the lipid profile can significantly enhance the application of this valuable fungus across various fields, including nutrition and medicine. However, to date, there is limited knowledge regarding the effects of different drying methods on the quality of lipids present in Cordyceps sinensis. In this study, we employed a broadly targeted lipidomic strategy to conduct a comprehensive analysis of the lipid composition in Cordyceps sinensis subjected to various drying methods. A comprehensive analysis identified a total of 765 distinct lipid species from fresh Cordyceps sinensis (FC), vacuum-freeze-dried Cordyceps sinensis (VG), oven-dried Cordyceps sinensis (OG), and air-dried Cordyceps sinensis (AG). Among these, glycerophospholipids (GP) were the most abundant, followed by glycerides (GL) and sphingolipids (SP). In this study, a total of 659 lipids demonstrated statistically significant differences, as indicated by a p-value (p) < 1. Among these lipids, triglycerides (TG) exhibited the highest concentration, followed by several others, including ceramide-ascorbic acid (Cer-AS), phosphatidylethanolamine (PE), lysophosphatidylcholine (LPC), and phosphatidylserine (PS). OG was the fastest drying method; however, PCA and OPLS-DA analyses indicated that the most significant changes in the lipids of Cordyceps sinensis were observed under the OG method. Specifically, 517 differentially accumulated lipids were significantly down-regulated, while only 10 lipids were significantly up-regulated. This disparity may be attributed to the degradation and oxidation of lipids. The metabolic pathways of glycerolipid, glycerophospholipid, and cholesterol are critical during the drying process of Cordyceps sinensis. This study provides valuable insights that can enhance quality control and offer guidelines for the appropriate storage of this medicinal fungus.
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7 Foods and Nutrients Proven To Cut Macular Degeneration Risk
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A fully organic retinal prosthesis restores vision in a rat model of d (...)
Nature Materials - A retinal prosthesis fabricated from an organic photovoltaic polymer can restore degenerative blindness in vivo, and over long implantation periods.
A Homeopathic Approach to Macular Degeneration Treatment Success Story
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Bates Method - Techniques
Blurred Vision Everything You Need to Know! Healing the Eye
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Eye Drops to Replace Your Reading Glasses
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New iPad Amblyopia Treatment is a “Hot Topic”
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Proteomics and precision medicine Protein analysis can make diagnoses (...)
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Spinach Helps Protect Eyes from Macular Degeneration
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Treatment of Ocular Surface Squamous Neoplasia With Topical... Cornea
raphs to document changes over time with A. vera-based topical treatment. Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years. Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment....
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency Autophagy Vol 0, No ja
The accumulation of undegraded molecular material leads to progressive neurodegeneration in a number of lysosomal storage disorders (LSDs) that are caused by functional deficiencies of lysosomal hy...
Why Vitamins May Not Be Helping You - America's Favorite Eye Doctor - (...)
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Cerebral Palsy and Hyperbaric Oxygen Therapy at DuckDuckGo
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Cerebral Palsy Hyperbaric Oxygen Therapy | Cerebral Palsy Guidance
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Hyperbaric Oxygen Therapy
How Hyperbaric Oxygen Works Most illnesses and injuries occur, and often linger, at the cellular or tissue level. In many cases, such as circulatory problems, non-healing wounds, and strokes, adequate oxygen cannot reach the damaged area and the body’s natural healing ability is unable to function properly. The delivery of 100% oxygen under pressure during […]