2016

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Joel Richardson closes out his teaching on Revelation 19 in a bonus session covering Islamic Eschatology and how it relates to the Book of Revelation in THE ...

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱In a groundbrea...

Fibroblast growth factor 21 (FGF21) plays a crucial role in metabolism and brain function. Glucosamine (GLN) has been recognized for its diverse beneficial effects. This study aimed to elucidate the modulation of FGF21 production by GLN and its impact on learning and memory functions. Using both in vivo and in vitro models, we investigated the effects of GLN on mice fed with a normal diet or high-fat diet and on mouse HT22 hippocampal cells, STHdhQ7/Q7 striatal cells, and rat primary cortical neurons challenged with GLN. Our results indicated that GLN promotes learning and memory functions in mice and upregulates FGF21 expression in the hippocampus, cortex, and striatum, as well as in HT22 cells, STHdhQ7/Q7 cells, and cortical neurons. In animals receiving GLN together with an FGF21 receptor FGFR1 inhibitor (PD173074), the GLN-enhanced learning and memory functions and induction of FGF21 production in the hippocampus were significantly attenuated. While exploring the underlying molecular mechanisms, the potential involvement of NF-κB, Akt, p38, JNK, PKA, and PPARα in HT22 and NF-κB, Akt, p38, and PPARα in STHdhQ7/Q7 were noted; GLN was able to mediate the activation of p65, Akt, p38, and CREB in HT22 and p65, Akt, and p38 in STHdhQ7/Q7 cells. Our accumulated findings suggest that GLN may increase learning and memory functions by inducing FGF21 production in the brain. This induction appears to be mediated, at least in part, through GLN’s activation of the NF-κB, Akt, p38, and PKA/CREB pathways.

Natural rare sugars are an alternative category of sweeteners with positive physiologic and metabolic effects both in in vitro and animal models. D-allulose is a D-fructose epimer that combines 70% sucrose sweetness with the advantage of an extremely low energy content. However, there are no data about the effect of D-allulose against adipose dysfunction; thus, it remains to be confirmed whether D-allulose is useful in the prevention and in treatment of adipose tissue alterations. With this aim, we evaluated D-allulose’s preventive effects on lipid accumulation in 3T3-L1 murine adipocytes exposed to palmitic acid (PA), a trigger for hypertrophic adipocytes. D-allulose in place of glucose prevented adipocyte hypertrophy and the activation of adipogenic markers C/EBP-β and PPARγ induced by high PA concentrations. Additionally, D-allulose pretreatment inhibited the NF-κB pathway and endoplasmic reticulum stress caused by PA, through activation of the Nrf2 pathway. Interestingly, these effects were also observed as D-allulose post PA treatment. Although our data need to be confirmed through in vivo models, our findings suggest that incorporating D-allulose as a glucose substitute in the diet might have a protective role in adipocyte function and support a unique mechanism of action in this sugar as a preventive or therapeutic compound against PA lipotoxicity through the modulation of pathways connected to lipid transport and metabolism.

Learn about your kidneys, how to protect them, and what to eat when you have kidney disease! Dr. Sean Hashmi is a Board Certified Nephrologist and Michele Crosmer is a Registered Dietitian and Certified Specialist in Renal Nutrition. We hope to educate and empower you to take control of your health and make proactive lifestyle choices to protect kidney health! Thanks so much for subscribing to our channel! Sean Hashmi, MD, MS, FASN and Michele Crosmer, RD, CSR

Hello, dear friends! I'm Dr. Sean Hashmi, founder of SELF Principle, a community focused on the latest research in nutrition, longevity, health, wellness, and kidney disease. As a father, husband, and kidney disease specialist, my journey in medicine began with personal loss and my family's health struggles. These experiences ignited my passion to explore the healing power of nutrition and wellness. Here, we'll delve into scientific insights, engaging expert interviews, and real stories. More than just learning, this channel is about connecting, growing, and supporting one another on the path to better health. Your thoughts, challenges, and triumphs matter to me, so please SUBSCRIBE and join our VIP list by hitting the bell. Together, we'll embark on a journey toward understanding, compassion, and wellness. With heartfelt gratitude, Sean Hashmi, MD, MS, FASN

Many have abandoned the media’s desperate attempt to ignore why cancer rates are spiking. Now, the American Cancer Society is sounding the alarm, predicting an 80% increase in tumors by 2050. Meanwhile, independent researchers have stepped up and honed in on credible sources pointing to the mass COVID vaccine rollout in 2021 as the prime […]

In this podcast episode, Dr. Ardis explores the controversial topic of nicotine, challenging commonly held beliefs about its addictiveness and highlighting its potential benefits for health. He discus

Watch this explosive interview with Dr. Bryan Ardis and Jason Shurka exposing the truth, origin, and unexpected antidote for C19 that ravaged the world. Dr. Bryan Ardis is a renowned doctor and resear

(NaturalHealth365) Explore the compounds within plant foods that target cancer cells. Uncover the natural weapons in fruits and vegetables.

(NaturalHealth365) Prolonged Benadryl use may pose a grave threat to brain health. Explore the unsettling findings of a new study.

(NaturalHealth365) Is chronic fatigue syndrome triggered by a leaky gut? Researchers found a connection between the gut and chronic fatigue.

Phosphatidylcholine benefits several parts of the body, including the brain, gut and more. Find out what it is, how to take it and more.

If you're familiar with nootropics supplements, you may have come across the compound called acetylcholine. So what is it and what does it do? Find out.

(NaturalHealth365) The nutritional benefits of beets are well known. A new study shows their betalains improve athletic performance as well.

(NaturalHealth365) Chlorine in tap water has been linked to colorectal and bladder cancer. Find out how to lower your risk naturally.

AUDIO ONLY: Timothy Mahoney concludes his discussion with Dr. Fred Baltz about the Sudarium of Oviedo, believed by many to be the burial face cloth of Jesus referenced in the Gospel of John, Chapter 20. What kind of scientific analysis was used to study the Sudarium and what did the team conducting the analysis find? What additional connections have been made between the Sudarium and the Shroud of Turin? What does it mean for us today if these cloths are authentic? NOTE: This episode (Episode 2) is available on YouTube as audio only, please consider joining our Patterns+ platform to see the video version. In doing so you will receive special weekly content on Bible affirming evidence from the realms of archaeology and science, as well as theological subjects. Your subscription will also support us in the production of new Patterns of Evidence films. Help us continue to share and preserve the historical credibility of the Bible and evidence. JOIN NOW: https://digitalpatternsofevidence.vhx.tv/checkout/subscribe/purchase ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ -- Patterns of Evidence Quick Links -- ► SHOP ONLINE - https://store.patternsofevidence.com/ ► BECOME A MEMBER - https://digitalpatternsofevidence.vhx.tv/historical-faith-society ► DONATE - https://patternsofevidence.com/donations/ ► THINKER UPDATES - https://patternsofevidence.com/sign-up/ ► PRESS INQUIRIES - https://patternsofevidence.com/press/ ► PATTERNS+ - https://digitalpatternsofevidence.vhx.tv/checkout/subscribe/purchase -- Find us on Social Media -- ► Facebook - https://www.facebook.com/PatternsofEvidence ► Twitter - https://twitter.com/pattofevidence ► Instagram - https://www.instagram.com/patternsofevidence/ ► YouTube - https://www.youtube.com/patternsofevidence ► LinkedIn - https://www.linkedin.com/company/patterns-of-evidence

In this new 2-part series, Timothy Mahoney interviews Dr. Fred Baltz about a mysterious cloth some believe to be the burial face cloth of Jesus referenced in John Chapter 20. Is the Sudarium of Oviedo that very cloth? How does it relate to the Shroud of Turin? And what evidence exists pointing to its authenticity? We hope you enjoy this engaging discussion with Resurrection Sunday just having happened. NOTE: Episode 2 of this series will be available on YouTube as audio only, please consider joining our Patterns+ platform to see the video version. In doing so you will receive special weekly content on Bible affirming evidence from the realms of archaeology and science, as well as theological subjects. Your subscription will also support us in the production of new Patterns of Evidence films. Help us continue to share and preserve the historical credibility of the Bible and evidence. JOIN NOW: https://digitalpatternsofevidence.vhx.tv/checkout/subscribe/purchase ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ -- Patterns of Evidence Quick Links -- ► SHOP ONLINE - https://store.patternsofevidence.com/ ► BECOME A MEMBER - https://digitalpatternsofevidence.vhx.tv/historical-faith-society ► DONATE - https://patternsofevidence.com/donations/ ► THINKER UPDATES - https://patternsofevidence.com/sign-up/ ► PRESS INQUIRIES - https://patternsofevidence.com/press/ ► PATTERNS+ - https://digitalpatternsofevidence.vhx.tv/checkout/subscribe/purchase -- Find us on Social Media -- ► Facebook - https://www.facebook.com/PatternsofEvidence ► Twitter - https://twitter.com/pattofevidence ► Instagram - https://www.instagram.com/patternsofevidence/ ► YouTube - https://www.youtube.com/patternsofevidence ► LinkedIn - https://www.linkedin.com/company/patterns-of-evidence

There were 3 sets of Eyewitnesses to Jesus' Resurrection that ACTUALLY saw it happen, not just those who encountered the risen Savior later. 3 sets of witnesses who were actually there. They are witnesses most know about but haven't thought about completely, and thus don't realize their significance. Click here to watch this Nelson Walters video and discover who they were and what they saw. This video contains AI images from our AI Artist team including Christian Vichi, Robert Forsbach, Jonathan Merrill, Jason Lawrence, and FreethroughChrist

Was the resurrection of Christ the fulfillment of an Old Testament festival? What is the meaning of it? And what is the Jewish view of it? Subscribe to our YouTube Channel: https://buff.ly/36cDNpo Pre-Order Amir’s new book "Discovering Daniel": https://discoveringdaniel.com Follow us on social media: Instagram: https://www.instagram.com/beholdisrael/ Facebook: https://www.facebook.com/beholdisrael/ Telegram: https://t.me/beholdisraelchannel Visit our website: https://beholdisrael.org Public Reading of Scripture: http://beholdprs.org DVD’s & Digital Downloads: https://shop.beholdisrael.org Latest Middle East News: https://beholdisrael.org/news/ Bible Teachings: https://beholdisrael.org/watch-and-listen/bible-teachings/ Articles: https://beholdisrael.org/articles/ Teaching Around the World: https://beholdisrael.org/teaching-around-the-world/ Bible Experience Tours: https://beholdisrael.org/bible-experience-tours/

Is the April 8 Eclipse a Symbol of God's Judgment or not? It IS the most anticipated eclipse in history with the National Guard already called out to control the crowds. But how can we decide if it's a sign from God or that judgment is coming? Click here to watch this Nelson Walters video to discover how to decide if it's a warning of God's judgment on the USA and when that might happen. This video contains AI images from our AI Artist team including Christian Vichi, Robert Forsbach, Jonathan Merrill, Jason Lawrence, and FreethroughChrist

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 In this episode of The Empowering Neurologist, we're diving into two topics that are gaining significant attention in the worlds of men's health and weight loss: the importance of testosterone replacement therapy and the emerging role of GLP-1 agonists in weight loss as well as in diabetes treatment. Joining us is an esteemed expert in this field, Dr. Tracy Gapin, a renowned urologist and men's health specialist. Why is this topic so crucial? Testosterone, often hailed as the cornerstone of male vitality, plays a central role in various aspects of men's health. It's not just about physical strength or libido; testosterone impacts mood, energy levels, bone density, muscle mass, cognitive function, and overall well-being. However, as men age, testosterone levels naturally decline, leading to a condition known as hypogonadism or low testosterone. This decline can have profound effects on a man's health and quality of life. Dr. Gapin, with his extensive experience and research in the field, sheds light on how testosterone replacement therapy can be a game-changer for men experiencing the effects of low testosterone. He delves into the nuances of identifying candidates for this therapy, the benefits, and the misconceptions surrounding it. His insights are particularly valuable in a time when discussions about men's hormonal health are often overshadowed or misunderstood. Further, as he explains, age-matched testosterone levels in men have plummeted over the past several decades, and we discuss why. In addition, Dr. Gapin takes us through the exciting world of GLP-1 agonists, a class of drugs initially developed for diabetes management but now having a major impact in the weight loss arena. Obesity is a mounting concern globally, and its impact on men's health is undeniable. With cardiovascular disease, diabetes, and a host of other conditions linked to obesity, finding effective weight management solutions is paramount. Dr. Gapin explains how GLP-1 agonists work, their benefits, their potential risks, and their role in revolutionizing weight loss treatments. This episode is not just for those directly experiencing these issues but also for anyone interested in the broader conversation about men's health. Whether you're a healthcare professional, someone exploring options for personal health improvement, or simply curious about the latest in medical advancements, Dr. Gapin's insights offer valuable knowledge and perspective. ==== 0:00 Intro 3:04 The Issues of Low Testosterone 7:07 Why Testosterone Levels are Falling 10:00 What Indicates Low Testosterone 15:00 The Holistic Approach to This 17:28 Why Testosterone Replacement Therapy May Be Essential 19:53 Addressing Potential Risks 28:20 How TRT Works & What to Expect 35:49 Looking at Estrogen and Progesterone 37:23 LDL Medication and Low Testosterone 39:55 Addressing Thyroid Functionality 40:56 Honest Thoughts on Ozempic 50:28 Conclusion ==== Tracy Gapin, MD, is a board-certified urologist, men’s health and performance expert. and founder of the Gapin Institute, a global leader in high performance medicine. He has over 20 years of experience focused on providing executives, entrepreneurs and athletes a personalized path to optimizing their health so they can have exceptional energy, laser-focused mind and a better body. He attended Texas A&M University. He went to medical school at UT Southwestern in Dallas, and he completed his general surgery and urology training at the University of Florida. He spent almost 20 years in a busy urology practice in Sarasota, Florida, where he specialized in robotic surgery, minimally invasive treatment for prostate cancer and men's health before launching the Gapin Institute. He’s a fellow of the American College of Surgeons, and a member of the American Academy of Anti-Aging.  Gapin is a thought leader, a professional speaker and the author of the best-selling books “Male 2.0” and “Codes of Longevity.” Text HEALTH to 26786 to receive an electronic copy of the High Performance Health Handbook for Men ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

Testosterone is NOT the Cause of Post Menopausal Hair Loss

Inflammation is the initial response of the immune system to potentially harmful stimuli (e.g., injury, stress, and infections). The process involves activation of macrophages and neutrophils, which produce mediators, such as nitric oxide (NO), prostaglandin ...

Background: Aloe vera is a medically valuable plant with anti-epileptic activity; however, its mechanism of action remains unknown. In this study, network pharmacological, in vitro, and in vivo experiments were carried out to explore the potential anti-epileptic component …

By Richard J Johnson MD DrRichardJohnson.com Chronic kidney disease is not uncommon in the United States, with as many as 15 percent of all adults manifesting some decrease in kidney …

Fucoidin failed to protect the kidney from ischemic damage and was even nephrotoxic. It also stimulated the formation of iNOS RNA.