Alzheimer’s disease (AD) is the most common form of dementia. However, the etiopathogenesis of this devastating disease is not fully understood. Recent studies in rodents suggest that alterations in the gut microbiome may contribute to amyloid ...
Mineral Water Found to Reduce the Symptoms of Alzheimers Disease
Major supermarkets are deceiving us in one of the worst ways possible - by deliberately boycotting products that can reverse the damage caused by continuous exposure to toxic aluminum.
New link found between diabetes, Alzheimers disease -- ScienceDaily
Drugs used to treat diabetes could also be used to treat Alzheimer's disease, and vice versa, according to new research. This is also the first study of its kind to show that Alzheimer's disease can lead to diabetes, as opposed to diabetes occurring first as was previously thought.
Nutrition and Alzheimers disease the detrimental role of a high carbo (...)
Alzheimer's disease is a devastating disease whose recent increase in incidence rates has broad implications for rising health care costs. Huge amounts of research money are currently being invested in seeking the underlying cause, with corresponding progress in understanding the disease progression …
Saffron vs. Memantine (Namenda) for Alzheimers - YouTube
The spice saffron is pitted head-to-head against the leading drug for severe Alzheimer’s disease.
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For more on herbal approaches to dementia, check out Best Aromatherapy Herb for Alzheimer's (https://nutritionfacts.org/video/best-aromatherapy-herb-for-alzheimers) and Treating Alzheimer's with Turmeric (https://nutritionfacts.org/video/treating-alzheimers-with-turmeric).
What else can saffron do? See:
• Saffron vs. Prozac (https://nutritionfacts.org/video/saffron-vs-prozac/)
• Saffron for the Treatment of PMS (https://nutritionfacts.org/video/saffron-for-the-treatment-of-pms/)
• Saffron for Erectile Dysfunction (http://www.nutritionfacts.org/topics/saffron-for-erectile-dysfunction)
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Diet may explain the Nigerian Paradox, where they have among the highest rates of the Alzheimer’s susceptibility gene, ApoE4, but among the lowest rates of Alzheimer’s disease.
Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/
What dietary changes? See some of my latest videos on preventing Alzheimer’s disease:
• Preventing Alzheimer’s with Lifestyle Changes (http://nutritionfacts.org/video/preventing-alzheimers-with-lifestyle-changes)
• Preventing Alzheimer’s Disease with Diet (http://nutritionfacts.org/video/preventing-alzheimers-disease-with-diet)
• Preventing Alzheimer’s Disease With Plants (http://nutritionfacts.org/video/Preventing-Alzheimers-Disease-With-Plants/)
• Reducing Glycotoxin Intake to Prevent Alzheimers (http://nutritionfacts.org/video/Reducing-Glycotoxin-Intake-to-Prevent-Alzheimers)
• Alzheimer’s May Start Decades Before Diagnosis (http://nutritionfacts.org/video/alzheimers-may-start-decades-before-diagnosis)
• Alzheimer’s and Atherosclerosis of the Brain (http://nutritionfacts.org/video/alzheimers-and-atherosclerosis-of-the-brain)
• Cholesterol and Alzheimer’s disease (http://nutritionfacts.org/video/cholesterol-and-alzheimers-disease)
This concept of switching genes on and off is the exciting world of epigenetics. For more, see BRCA Breast Cancer Genes (http://nutritionfacts.org/video/brca-breast-cancer-genes-and-soy/) and Soy and Cancer Reversal Through Diet? (http://nutritionfacts.org/video/cancer-reversal-through-diet/).
Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/the-alzheimers-gene-controlling-apoe and he'll try to answer it!
Image Credit: PublicDomainPictures via Pixabay.
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Treatment with vitamin C dissolves toxic protein aggregates in Alzheim (...)
Researchers in Sweden have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease.
Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimers Disease. - PubMed - NCBI
This study assessed the therapeutic utility of the autophagy enhancing stable disaccharide trehalose in the Tg2576 transgenic mouse model of Alzheimer's disease (AD) via an oral gavage of a 2% trehalose solution for 31 days. Furthermore, as AD is a neurodegenerative condition in which the transition …
Turmeric Produces 'Remarkable' Recovery in Alzheimers Patients
Turmeric has been used in India for over 5,000 years, which is likely why still today both rural and urban populations have some of the lowest prevalence rates of Alzheimer's disease (AD) in the world. A study on patients with AD found that less than a gram of turmeric daily, taken for three months, resulted in 'remarkable improvements'
Frontiers Microbiome-derived lipopolysaccharide (LPS) enriched in the (...)
Abundant clinical, epidemiological, imaging, genetic, molecular, and pathophysiological data together indicate that there occur an unusual inflammatory reaction and a disruption of the innate-immune signaling system in Alzheimer’s disease (AD) brain. Despite many years of intense study, the origin and molecular mechanics of these AD-relevant pathogenic signals are still not well understood. Here, we provide evidence that an intensely pro-inflammatory bacterial lipopolysaccharide (LPS), part of a complex mixture of pro-inflammatory neurotoxins arising from abundant Gram-negative bacilli of the human gastrointestinal (GI) tract, are abundant in AD-affected brain neocortex and hippocampus. For the first time, we provide evidence that LPS immunohistochemical signals appear to aggregate in clumps in the parenchyma in control brains, and in AD, about 75% of anti-LPS signals were clustered around the periphery of DAPI-stained nuclei. As LPS is an abundant secretory product of Gram-negative bacilli resident in the human GI-tract, these observations suggest (i) that a major source of pro-inflammatory signals in AD brain may originate from internally derived noxious exudates of the GI-tract microbiome; (ii) that due to aging, vascular deficits or degenerative disease these neurotoxic molecules may “leak” into the systemic circulation, cerebral vasculature, and on into the brain; and (iii) that this internal source of microbiome-derived neurotoxins may play a particularly strong role...
An aging specialist discusses 10 main signs of Alzheimer's disease and the importance of obtaining an early diagnosis. More than 5 million people in the United States have Alzheimer's disease, according to the Alzheimer's Association. Not only is Alzheimer's disease the sixth leading cause of death in the country, but it also currently cannot be prevented, cured or slowed.
Understanding how chemical changes in the brain affect Alzheimers dis (...)
A new study is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life. The study used mouse models to show that long-term suppression of the neurotransmitter acetylcholine -- a target for anticholinergic drugs -- results in dementia-like changes in the brain.
Vicious circle of platelets Alzheimers disease patients may benefit f (...)
Inhibition of platelets in Alzheimer's disease patients may become important in therapy in future, say researchers whose findings could be of great importance for the treatment of Alzheimer's disease patients.