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Clinical Studies & Research | Dementia Trial
Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project - IOS Press
Background: Effective therapeutics for Alzheimer’s disease are needed. However, previous clinical trials have pre-determined a single treatment modality, such as a drug candidate or therapeutic procedure, which may be unrelated to the primary drivers
1 Brain Health Breakthroughs – Awakening from Alzheimer's
! 1 The Intriguing Connection Between the Gut Microbiome and Parkinson's Disease - David Perlmutter M.D.
For years, the medical community has viewed Parkinson’s Disease (PD) primarily as a neurological disorder, defined by its hallmark motor symptoms such as tremors, rigidity, and postural instability. However, recent …
The Health Benefits of Creatine Supplementation - David Perlmutter M.D.
Should you take a creatine supplement? This is a frequent question I get asked when I lecture, as well as on various online forums. Ultimately, I think it makes a …
Integrated Multimodal Omics and Dietary Approaches for the Management of Neurodegeneration
Neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease, are caused by a combination of multiple events that damage neuronal function. A well-characterized biomarker of neurodegeneration is the accumulation of proteinaceous aggregates in the brain. However, the gradually worsening symptoms of neurodegenerative diseases are unlikely to be solely due to the result of a mutation in a single gene, but rather a multi-step process involving epigenetic changes. Recently, it has been suggested that a fraction of epigenetic alternations may be correlated to neurodegeneration in the brain. Unlike DNA mutations, epigenetic alterations are reversible, and therefore raise the possibilities for therapeutic intervention, including dietary modifications. Additionally, reactive oxygen species may contribute to the pathogenesis of Alzheimer’s disease and Parkinson’s disease through epigenetic alternation. Given that the antioxidant properties of plant-derived phytochemicals are likely to exhibit pleiotropic effects against ROS-mediated epigenetic alternation, dietary intervention may be promising for the management of neurodegeneration in these diseases. In this review, the state-of-the-art applications using single-cell multimodal omics approaches, including epigenetics, and dietary approaches for the identification of novel biomarkers and therapeutic approaches for the treatment of neurodegenerative diseases are discussed.
Eat Your (Dark Green) Vegetables for Better Brain Health - David Perlmutter M.D.
We’ve heard for years that a diet rich in fruits and vegetables is the cornerstone of good health. In recent years, a particular group of vegetables – dark green leafy …
Poor Gut Health Linked To Parkinson’s Disease | NaturalHealth365
(NaturalHealth365) A new study links poor gut health to the increased risk of Parkinson's disease. Find out how to reduce your risk.
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Probiotic Strain May Slow Cognitive Decline | NaturalHealth365
(NaturalHealth365) Research reveals that the benefits of this specific probiotic strain go well beyond gut health.
Constipation May Signal Cognitive Decline | NaturalHealth365
(NaturalHealth365) Evidence is emerging that chronic constipation is a sign that one’s cognitive functionality is worsening.
Lisa Mosconi: How menopause affects the brain | TED Talk
Many of the symptoms of menopause -- hot flashes, night sweats, insomnia, memory lapses, depression and anxiety -- start in the brain. How exactly does menopause impact cognitive health? Sharing groundbreaking findings from her research, neuroscientist Lisa Mosconi reveals how decreasing hormonal levels affect brain aging -- and shares simple lifestyle changes you can make to support lifelong brain health.
The XX Brain, by Lisa Mosconi, PhD
New Book on the Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease. Intro by Maria Shriver. Includes chapters on Alzheimer's Disease, dementia, brain aging, menopause, perimenopause, women's health, HRT, neuroscience, and other related topics.
Blueberries Protect Against Cognitive Decline | NaturalHealth365
(NaturalHealth365) New research shows that blueberries, bursting with antioxidants, can help reduce the risk of Alzheimer's disease.
! Alzheimer's Disease and the Amyloid Hypothesis: A Rethink is Required - David Perlmutter M.D.
In recent years, the dominant theory guiding research on Alzheimer’s Disease (AD) treatment has been the “Amyloid Cascade Hypothesis”. This hypothesis suggests that the accumulation of amyloid-beta protein in the …
The Alarming Rise in Parkinson’s Disease: w/ Dr. Ray Dorsey - David Perlmutter M.D.
Welcome one and all to another enlightening episode of The Empowering Neurologist. Joining us is Dr. Ray Dorsey, Professor of Neurology at the University of Rochester, a stalwart advocate for …
The Alarming Rise in Parkinson’s Disease with Dr. Ray Dorsey | The Empowering Neurologist EP. 167 - YouTube
Welcome one and all to another enlightening episode of The Empowering Neurologist. Joining us is Dr. Ray Dorsey, Professor of Neurology at the University of ...
Pomegranates Lower Neuroinflammation | NaturalHealth365
(NaturalHealth365) Did you know pomegranates can help to protect brain health? Find out how this fruit can support cognitive function.
Awakening From Alzheimers
The Alzheimer’s Solution
Our Bestselling Books The 30-Day Alzheimer’s Solution Together, we can positively affect the most important organ in the body for billions of people with effective tools and methodologies. Our personalized, comprehensive programs for brain healthy living are programs that people can follow for the rest of their lives. BUY NOW: The action plan that you […]
Natural Remedies for ALS
Natural treatments for ALS, or Lou Gehrig's Disease, include supplements including Vitamins C and E, and B Complex.
Sauna Use Lowers Risk Of Alzheimer’s Disease | NaturalHealth365
(NaturalHealth365) Studies show that regular sauna usage will greatly reduce your risk of Alzheimer's disease. Learn more about this therapy.
Download the SAGE test | Ohio State Medical Center
Here is some info from Ohio State – improving lives through excellence in research, education and patient care.
Brain Health Preserved By This Nutrient | NaturalHealth36
(NaturalHealth365) Insights from a recent study reveal surprising connection between magnesium and brain health.
Parkinson's Disease Invisible Cause Revealed | NaturalHealth365
(NaturalHealth365) Common environmental contaminant frequently present in tap water may increase your risk of Parkinson's disease.
How to Fix Your Leaky Brain - David Perlmutter M.D.
A relatively new player in the discussion of factors leading to Alzheimer’s is the breakdown of the so-called blood-brain barrier (BBB). The blood-brain barrier is essentially a checkpoint within the …
Vitamin D and Dementia Risk - David Perlmutter M.D.
For years I’ve been writing about the important role of vitamin D as it relates to general health and brain health in specific. And with good reason. The medical research …
Treating Alzheimer's with Fecal Material - David Perlmutter M.D.
In 2015, I published Brain Maker, a book that explored the remarkable, but generally overlooked relationship between the gut and the brain. These days, this relationship gets a lot of …