Alzheimers Parkinsons ALS

Drugs being used to treat Alzheimer’s disease are actually associated with a more aggressive decline in cognitive function.

2019 RYB ALZ Risk - Main Opt-In.

This is the first time a randomized, double-blind, clinical trial has shown that a nutritional intervention can help to conserve the ability of prodromal AD patients to carry out everyday tasks, such as paying bills, or finding your way around, as measured by the Clinical Dementia Rating-Sum of Boxes (CDR-SB) -- a combined measure for the ability to think and perform everyday tasks. This is important because those with prodromal AD currently have no approved, available pharmacological options.

Exercise, which has a positive impact on brain health, needs to be front and center in terms of our Alzheimer’s messaging and outreach.

The disaccharide trehalose is commonly considered to stimulate autophagy. Cell treatment with trehalose could decrease cytosolic aggregates of potentially pathogenic proteins, including mutant huntingtin, α-synuclein, and phosphorylated tau that are associated with neurodegenerative diseases. Here, …

A new study highlights the role lifestyle factors, like sleep, exercise, stress, and weight gain can have on your risk of developing Alzheimer's disease.

Do you ever worry about you or a loved one getting Alzheimer’s disease? It’s heartbreaking to watch someone you love not remember who you are or have difficulties with everyday tasks. The sacred plant is effective in preventing these symptoms of cognitive decline by reducing brain inflammation due to aging and by restoring a process called neurogenesis. Watch as Dr. Daniel Stein, a cannabis Neurologist, shares what he refers to as a “type 3” preventative protocol. *** This limited clip is a preview from our Healing Brain Masterclass. Get full access to our entire 3 masterclass library, complete season 1 docuseries, and over 37 bonuses on a portable 100+ GB flash drive... Go here for all the details 👉 http://bit.ly/2rl3F33

New research has found a way to partially restore brain cell communication around areas damaged by plaques associated with Alzheimer's disease.

Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 …

Transgenic APPswe/PS1dE9 mice modeling Alzheimer’s disease demonstrate ongoing accumulation of β-amyloid fragments resulting in formation of amy...

The Alzheimer's brain can't handle glucose effectively, which is why this unique saturated fat may hold the key to improving and even reversing the condition in some patients

New research connects some very important dots and gives further substantiation to the idea that coffee is good for the brain.

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Contrary to conventional wisdom, brain regeneration is possible. One promising therapy that promotes neurogenesis and is effective in pre-clinical studies of Alzheimer’s and Parkinson’s is near infrared light therapy, and it may improve other mental illnesses and neurodegenerative disorders including dementia, stroke, ALS, and traumatic brain injury as well

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder. As the aging population is increasing, AD is becoming one of the leading causes of disability and death among the elderly. However, currently there is no cure for this disease. Fucoidan is a complex sulfated polysaccharide ma

Glucose and glucose metabolites are able to adversely modify proteins through a non-enzymatic reaction called glycation, which is associated with the pathology of Alzheimer’s Disease (AD) and is a characteristic of the hyperglycaemia induced by diabetes. However, the precise protein glycation profile that characterises AD is poorly defined and the molecular link between hyperglycaemia and AD is unknown. In this study, we define an early glycation profile of human brain using fluorescent phenylboronate gel electrophoresis and identify early glycation and oxidation of macrophage migration inhibitory factor (MIF) in AD brain. This modification inhibits MIF enzyme activity and ability to stimulate glial cells. MIF is involved in immune response and insulin regulation, hyperglycaemia, oxidative stress and glycation are all implicated in AD. Our study indicates that glucose modified and oxidised MIF could be a molecular link between hyperglycaemia and the dysregulation of the innate immune system in AD.

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Alzheimer's disease is a neurodegenerative disorder involving extracellular plaques (amyloid-β) and intracellular tangles of tau protein. Recently, tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oli …