Alzheimers Parkinsons ALS

Glucose and glucose metabolites are able to adversely modify proteins through a non-enzymatic reaction called glycation, which is associated with the pathology of Alzheimer’s Disease (AD) and is a characteristic of the hyperglycaemia induced by diabetes. However, the precise protein glycation profile that characterises AD is poorly defined and the molecular link between hyperglycaemia and AD is unknown. In this study, we define an early glycation profile of human brain using fluorescent phenylboronate gel electrophoresis and identify early glycation and oxidation of macrophage migration inhibitory factor (MIF) in AD brain. This modification inhibits MIF enzyme activity and ability to stimulate glial cells. MIF is involved in immune response and insulin regulation, hyperglycaemia, oxidative stress and glycation are all implicated in AD. Our study indicates that glucose modified and oxidised MIF could be a molecular link between hyperglycaemia and the dysregulation of the innate immune system in AD.

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Alzheimer's disease is a neurodegenerative disorder involving extracellular plaques (amyloid-β) and intracellular tangles of tau protein. Recently, tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oli …

Omega-3 fatty acids are known to be good for heart health, but did you know that in high doses they may also slow cognitive decline?

Muses Labs, partnering with leading Alzheimer's researchers, pioneered the MEND™ Protocol to treat underlying drivers of Alzheimer’s disease with big-data.

Dementia and Alzheimer's a big problem in industrialized countries. With the aging population at greater and greater risk for these conditions, it is imperative to understand that there are a variety of natural ways to stop dementia in its tracks. In this video, Dr. Osborne breaks down 6 natural ways you can overcome brain inflammation (brainflammation) including: 1. Avoid gluten 2. Eat lots of healthy fats 3. Avoid eating excessive carbohydrates 4. Take exercise more seriously 5. Maintain a healthy blood sugar 6. Do a medication review with your doctor. Remember, natural help is all about your diet and your lifestyle. There are no magic cures. You have to put in the work. To connect with Dr. Osborne visit: Facebook: https://www.facebook.com/DoctorPeterO... Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.

A new study provides additional evidence that amyloid-beta protein -- which is deposited in the form of beta-amyloid plaques in the brains of patients with Alzheimer's disease -- is a normal part of the innate immune system, the body's first-line defense against infection.

In a new study, compared with the standard diet, patients on the ketogenic diet showed a small trend towards improved cognition.

Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier of people with early Alzheimer's disease, according to a new study. The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the disease.

Contrary to mainstream medical belief, safe, natural, and nontoxic treatments can alleviate the symptoms of senile dementia. Research has demonstrated how these remedies can aid in preventing the onset of senile dementia.

Researchers have identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease.

A new study has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer's Disease.Periodontitis or gum disease is common in older people and may become more common in Alzheimer's disease because of a reduced ability to take care of oral hygiene as the disease progresses. Higher levels of antibodies to periodontal bacteria are associated with an increase in levels of inflammatory molecules elsewhere in the body, which in turn has been linked to greater rates of cognitive decline in Alzheimer's disease in previous studies. The latest study set out to determine whether periodontitis or gum disease is associated with increased dementia severity and subsequent greater progression of cognitive decline in people with Alzheimer's disease.

Dr. Dale Bredesen's new book focuses on providing hands-on information to preserve our brains and heal from Alzheimer's and dementia.

Researchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease (AD). It is generally accepted that lifestyle and particularly dietary habits influence mental health, and prevalence and progression of AD. Numerous epidemiological studies have revealed profitable effects of dietary intake of especially fish oil on cognitive decline during aging and dementia.

Could the active ingredient in marijuana, responsible for its characteristic "high," help turn the tide against the accelerating Alzheimer's epidemic? A remarkable study published in the journal Molecular Pharmacology in 2006, found that this long vilified plant may contain a compound with not one, but two therapeutic properties ideal for addressing both the surface symptom (memory problems) and root cause (brain plaque) of Alzheimer’s disease

Neurons affected in Alzheimer’s disease (AD) experience mitochondrial dysfunction and a bioenergetic deficit that occurs early and promotes the disease-defining amyloid β-peptide (Aβ) and Tau pathologies. Emerging findings suggest ...

Older adults with low intake of foods and drinks containing flavonoids, such as berries, apples, and tea, were more likely to develop Alzheimer's disease and related dementias over 20 years, compared with people who consumed more of those items, according to a new study.

A supplement that stops the breakdown of the ACh neurotransmitter in the brain is a useful technique to trigger lucid dreams

Dr. Dale Bredesen has shown, using lifestyle changes like a ketogenic diet, that Alzheimer's Disease and dementia can be prevented and reversed.