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In a new study, compared with the standard diet, patients on the ketogenic diet showed a small trend towards improved cognition.

Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier of people with early Alzheimer's disease, according to a new study. The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the disease.

Researchers have identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease.

A new study has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer's Disease.Periodontitis or gum disease is common in older people and may become more common in Alzheimer's disease because of a reduced ability to take care of oral hygiene as the disease progresses. Higher levels of antibodies to periodontal bacteria are associated with an increase in levels of inflammatory molecules elsewhere in the body, which in turn has been linked to greater rates of cognitive decline in Alzheimer's disease in previous studies. The latest study set out to determine whether periodontitis or gum disease is associated with increased dementia severity and subsequent greater progression of cognitive decline in people with Alzheimer's disease.

Researchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease (AD). It is generally accepted that lifestyle and particularly dietary habits influence mental health, and prevalence and progression of AD. Numerous epidemiological studies have revealed profitable effects of dietary intake of especially fish oil on cognitive decline during aging and dementia.

Could the active ingredient in marijuana, responsible for its characteristic "high," help turn the tide against the accelerating Alzheimer's epidemic? A remarkable study published in the journal Molecular Pharmacology in 2006, found that this long vilified plant may contain a compound with not one, but two therapeutic properties ideal for addressing both the surface symptom (memory problems) and root cause (brain plaque) of Alzheimer’s disease

Contrary to conventional wisdom, brain regeneration is possible. One promising therapy that promotes neurogenesis and is effective in pre-clinical studies of Alzheimer’s and Parkinson’s is near infrared light therapy, and it may improve other mental illnesses and neurodegenerative disorders including dementia, stroke, ALS, and traumatic brain injury as well

Neurons affected in Alzheimer’s disease (AD) experience mitochondrial dysfunction and a bioenergetic deficit that occurs early and promotes the disease-defining amyloid β-peptide (Aβ) and Tau pathologies. Emerging findings suggest ...

Older adults with low intake of foods and drinks containing flavonoids, such as berries, apples, and tea, were more likely to develop Alzheimer's disease and related dementias over 20 years, compared with people who consumed more of those items, according to a new study.

A supplement that stops the breakdown of the ACh neurotransmitter in the brain is a useful technique to trigger lucid dreams

Dr. Dale Bredesen has shown, using lifestyle changes like a ketogenic diet, that Alzheimer's Disease and dementia can be prevented and reversed.

Alzheimer's disease (AD) is a leading killer of Americans, imparts a significant toll on the quality of life of the patient and primary caregiver, and results in inordinate costs in an already overburdened medical system. Prior studies on cholinesterase inhibitors among AD patients have shown minima …

Dr. David Perlmutter, author of Grain Brain, interview Dr. Dale Bredesen, the author of The End of Alzheimer's and a medical pioneer.

The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age [Bredesen, Dale, Perlmutter, David] on Amazon.com. *FREE* shipping on qualifying offers. The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

Today’s short video clip with Dr. Daniel Stein, dives deep into how to TREAT this horrific disease. You’ll discover the exact cannabinoids, terpenes and dosage protocol Dr. Stein recommends... *** This limited clip is a preview from our Healing Brain Masterclass. Get full access to our entire 3 masterclass library, complete season 1 docuseries, and over 37 bonuses on a portable 100+ GB flash drive... Go here for all the details 👉 http://bit.ly/2rl3F33

Abnormal accumulation of amyloid proteins is linked to neuronal degeneration in Alzheimer's disease brains, driving cognitive decline. Disruption of autophagy pathway contributes to the development o...

Alzheimer's disease is an irreversible and progressive brain disorder featured by the accumulation of Amyloid-β (Aβ) peptide, which forms insoluble assemblies that builds up into plaques resulting in cognitive decline and memory loss. The formation of fibrillar amyloid deposits is accompanied by con …

Transgenic mice with increased amyloid-β (Aβ) production show several aspects of Alzheimer’s disease, including Aβ deposition and memory impairment. By repeatedly treating these Aβ-forming mice with scanning ultrasound, Leinenga and Götz now demonstrate that Aβ is removed and memory is restored as revealed by improvement in three memory tasks. These improvements were achieved without the use of any therapeutic agent, and the scanning ultrasound treatment did not induce any apparent damage to the mouse brain. The authors then showed that scanning ultrasound activated resident microglial cells that took up Aβ into their lysosomes. These findings suggest that repeated scanning ultrasound may be a noninvasive method with potential for treating Alzheimer’s disease. Amyloid-β (Aβ) peptide has been implicated in the pathogenesis of Alzheimer’s disease (AD). We present a nonpharmacological approach for removing Aβ and restoring memory function in a mouse model of AD in which Aβ is deposited in the brain. We used repeated scanning ultrasound (SUS) treatments of the mouse brain to remove Aβ, without the need for any additional therapeutic agent such as anti-Aβ antibody. Spinning disk confocal microscopy and high-resolution three-dimensional reconstruction revealed extensive internalization of Aβ into the lysosomes of activated microglia in mouse brains subjected to SUS, with no concomitant increase observed in the number of microglia. Plaque burden was reduced in SUS-treated AD mice compared to sham-treated animals, and cleared plaques were observed in 75% of SUS-treated mice. Treated AD mice also displayed improved performance on three memory tasks: the Y-maze, the novel object recognition test, and the active place avoidance task. Our findings suggest that repeated SUS is useful for removing Aβ in the mouse brain without causing overt damage, and should be explored further as a noninvasive method with therapeutic potential in AD.

A new study in the journal Neurology explores the scientific fact behind the relationship between vitamin D and dementia and Alzheimer's

In California, people with Alzheimer's will be given transfusions of young blood to see if improves their cognition – there's good reason to hope it might

Alzheimer's disease is expanding unchecked throughout the modern world, despite billions spent annually on pharmaceutical interventions. Could the calcification of the brain play a role?

Fructose, Sunscreen, Statins and Flu Shots: a Recipe for Alzheimer's Disease.

Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood. Major bacterial species of the GI tract, such as the abundant Gram-negative bacilli Bacteroides fragilis (B. fragilis) and Escherichia coli (E. coli), secrete a remarkably complex array of pro-inflammatory neurotoxins which, when released from the confines of the healthy GI tract, are pathogenic and highly detrimental to the homeostatic function of neurons in the central nervous system (CNS). For the first time here we report the presence of bacterial lipopolysaccharide (LPS) in brain lysates from the hippocampus and superior temporal lobe neocortex of Alzheimer's disease (AD) brains. Mean LPS levels varied from two-fold increases in the neocortex to three-fold increases in the hippocampus, AD over age-matched controls, however some samples from advanced AD hippocampal cases exhibited up to a 26-fold increase in LPS over age-matched controls. This “Perspectives” paper will further highlight some very recent research on GI tract microbiome signaling to the human CNS, and will update current findings that implicate GI tract microbiome-derived LPS as an important internal contributor to inflammatory degeneration in the CNS.