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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection ...
·ncbi.nlm.nih.gov·
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Institutionalized Medical Malpractice & COVID
Institutionalized Medical Malpractice & COVID
It’s been over six weeks since Iowa dropped all state-level COVID restrictions, and surprise, surprise, hospitalized patients are down 54 percent. But if you try to Google this information, all you will see is death, dying, and it must be the end of the world because of COVID, which miraculously seems to be a cure... View Article
·drsircus.com·
Institutionalized Medical Malpractice & COVID
Investigation C0VlD Positive Results for People Who Were Never Given Tests - YouTube
Investigation C0VlD Positive Results for People Who Were Never Given Tests - YouTube
Hundreds of people across the United States have been complaining that they are receiving calls from clinics and medical offices claiming that they have confirmed positive for C0VlD but those people say they were never tested. Is this just an internet rumor or is it really happening? We're investigating. Check out our new free speech platform https://ISE.Media Invest in ISE Media: https://wefunder.com/ise.media ---------------- Support Truth in Media by visiting our sponsors: ISE.Media: https://ISE.Media Pulse Cellular: Use code "TRUTH" for 10% every plan for life. https://truthinmedia.com/phone Pure VPN: Military grade vpn protection. https://truthinmedia.com/vpn Brave Browser: Open source and built by a team of privacy focused, performance oriented pioneers of the web. https://truthinmedia.com/brave #benswann
·youtube.com·
Investigation C0VlD Positive Results for People Who Were Never Given Tests - YouTube
Microvascular dysfunction in COVID-19 the MYSTIC study SpringerLink
Microvascular dysfunction in COVID-19 the MYSTIC study SpringerLink
Rationale Pre-clinical and autopsy studies have fueled the hypothesis that a dysregulated vascular endothelium might play a central role in the pathogenesis of ARDS and multi-organ failure in COVID-19. Objectives To comprehensively characterize and quantify microvascular alterations in patients with COVID-19. Methods Hospitalized adult patients with moderate-to-severe or critical COVID-19 (n = 23) were enrolled non-consecutively in this prospective, observational, cross-sectional, multi-center study. Fifteen healthy volunteers served as controls. All participants underwent intravital microscopy by sidestream dark field imaging to quantify vascular density, red blood cell velocity (VRBC), and glycocalyx dimensions (perfused boundary region, PBR) in sublingual microvessels. Circulating levels of endothelial and glycocalyx-associated markers were measured by multiplex proximity extension assay and enzyme-linked immunosorbent assay. Measurements and main results COVID-19 patients showed an up to 90% reduction in vascular density, almost exclusively limited to small capillaries (diameter 4–6 µm), and also significant reductions of VRBC. Especially, patients on mechanical ventilation showed severe glycocalyx damage as indicated by higher PBR values (i.e., thinner glycocalyx) and increased blood levels of shed glycocalyx constituents. Several markers of endothelial dysfunction were increased and correlated with disease severity in COVID-19. PBR (AUC 0.75, p = 0.01), ADAMTS13 (von Willebrand factor-cleaving protease; AUC 0.74, p = 0.02), and vascular endothelial growth factor A (VEGF-A; AUC 0.73, p = 0.04) showed the best discriminatory ability to predict 60-day in-hospital mortality. Conclusions Our data clearly show severe alterations of the microcirculation and the endothelial glycocalyx in patients with COVID-19. Future therapeutic approaches should consider the importance of systemic vascular involvement in COVID-19.
·link.springer.com·
Microvascular dysfunction in COVID-19 the MYSTIC study SpringerLink