Diabetes Type 1

"Hit-and-run" treatment with senolytics, which in the case of D + Q have elimination half-lives

Conventional insulin concentration units (IU/mL or just U/mL) are bioefficacy based, whereas the Système International (SI) units (pmol/L) are mass based. In converting between these two different approaches, there are at least 2 well-accepted ...

After 20 years of treating patients and dealing with his own vein condition, Dr. Michael Ryan demonstrates his proven method of stopping a leg cramp in 15 se...

Check it out on AliExpress: https://s.click.aliexpress.com/e/_Ddxdwyr and be sure to come visit me at: https://www.DaveTheKayaker.com Also check out this blood glucose watch. So far I like it the most: https://youtu.be/4PzzQwqsWQw Subscribe and check out my "Fitness Tracker and Smartwatch Reviews" Playlist on YT. I like to bring you smartwatches that are new or different in some way, and this is the first one I've found with non-invasive blood glucose monitoring. #AliExpress #Smartwatch

What should we eat? I ask this question in the context of the incredible rates of obesity that we are now seeing, virtually worldwide. Today we will spend time with Dr. Jason Fung author of the book The Obesity Code. This is a landmark book that powerfully lays out why we are continuing to gain weight. It dispels the notion that dietary fat threatens to make us gain weight as well as the unfounded idea of calories in versus calories out as an explanation for why we gain weight. Dr. Fung clearly focuses on the importance of the hormone, insulin, in terms of obesity, and certainly in terms of diabetes as well. He outlines a very straightforward plan that is in perfect alignment with current science. This interview is one of the most fundamental as a relates to the science of weight loss and regaining control over our blood sugar. ==== 0:00 Intro 2:36 Why Dr. Fung Pursued Weight Loss Research 8:08 Problem with Insulin 15:15 Mechanisms of Insulin 23:09 Reconsidering Low Fat Diets & Calorie Counting 37:34 Satiety Hormones 40:10 Leptin & Weight Loss 43:59 Threat of Fructose 51:23 Conclusion ==== Dr. Jason Fung is a Canadian nephrologist and a world-leading expert on intermittent fasting and low carb, especially for treating people with type 2 diabetes. Dr. Fung graduated from the University of Toronto and completed his residency at the University of California, Los Angeles. He lives and works in Toronto, Canada. Here is Dr. Fung’s website: https://thefastingmethod.com/ https://www.dietdoctor.com/intermittent-fasting https://www.dietdoctor.com/low-carb https://www.dietdoctor.com/diabetes ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

Know Labs, an emerging leader in non-invasive medical diagnostics, introduced the KnowU™, a new portable medical-grade glucose monitoring device that utilizes Bio-RFID™, Know Labs’ non-invasive diagnostic technology. Related Supersapiens Glucose Display Wearable Is Designed Specifically For Athletes The KnowU is a convenient, non-wearable, on-the-go alternative to fingersticks, which are used to check blood glucose levels, Know Labs introduced KnowU, a new portable medical-grade glucose monitoring device that utilizes Bio-RFID.

Learn all about new continuous glucose monitors (CGM) that won’t poke the skin.

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Highlights • In 2 different mouse models, AKI increased Gal-3 expression and induced cardiac dysfunction, cardiac and systemic inflammation, cardiac macrophage infiltration, and fibrosis. • Cardiac...

Background Galectin-3 (Gal-3) is a pleiotropic glycan-binding protein shown to be involved in sepsis and acute kidney injury (AKI). However, its role has never been elucidated in sepsis-associated AKI (S-AKI). We aimed to explore Gal-3’s role and its potential utility as a therapeutic target in S-AKI. Methods In 57 patients admitted to the intensive care unit (ICU) with sepsis, serum Gal-3 was examined as a predictor of ICU mortality and development of AKI. In a rat model of S-AKI induced by cecal ligation and puncture (CLP), 7-day mortality and serum Gal-3, Interleukin-6 (IL-6), and creatinine were examined at 2, 8, and 24 hours (h) post-CLP. Two experimental groups received the Gal-3 inhibitor modified citrus pectin (P-MCP) at 400 mg/kg/day and 1200 mg/kg/day, while the control group received water only (n = 18 in each group). Results Among 57 patients, 27 developed AKI and 8 died in the ICU. Serum Gal-3 was an independent predictor of AKI (OR = 1.2 [95% CI 1.1–1.4], p = 0.01) and ICU mortality (OR = 1.4 [95% CI 1.1–2.2], p = 0.04) before and after controlling for age, AKI, and acute physiology and chronic health evaluation (APACHE II) score. In the CLP rat experiment, serum Gal-3 peaked earlier than IL-6. Serum Gal-3 was significantly lower in both P-MCP groups compared to control at 2 h post-CLP (400 mg: p = 0.003; 1200 mg: p = 0.002), and IL-6 was significantly lower in both P-MCP groups at all time points with a maximum difference at 24 h post-CLP (400 mg: p = 0.015; 1200 mg: p = 0.02). In the Gal-3 inhibitor groups, 7-day mortality was significantly reduced from 61% in the control group to 28% (400 mg P-MCP: p = 0.03) and 22% (1200 mg P-MCP: p = 0.001). Rates of AKI per RIFLE criteria were significantly reduced from 89% in the control group to 44% in both P-MCP groups (400 mg: p = 0.007; 1200 mg: p = 0.007). Conclusions This translational study demonstrates the importance of Gal-3 in the pathogenesis of S-AKI, and its potential utility as a therapeutic target. Graphic abstract

We evaluated Galectin-3 (Gal-3) as a potential early biomarker of acute kidney disease (AKI), and the effect of Gal-3 inhibition by modified citrus pe…

Plant Based Kidneys; Michele is a registered dietitian / certified specialist in renal nutrition. Self-study program, friendly plant based kidney recipes, blog.

Episode 19: Role of Vitamin K2 in Kidney Disease ⏰ Timestamps ⏰ 0:00 Introduction 0:45 What is Vitamin K and what is its role in kidney disease? 10:24 How do you get Vitamin K2 from your diet? 14:03 Why should you combine D3 with K2? 15:05 What dosage of K2 should you take? 16:30 Should you check your Vitamin K levels checked? 📱Subscribe and Listen to Plant Based Kidney Health Podcast HERE: Apple: https://apple.co/3tSO07m Spotify: https://spoti.fi/3tSGysP ⚡️Connect with us on Social Media: Sean Hashmi, MD, MS, FASN https://www.SELFPrinciple.org https://www.instragram.com/seanhashmimd Michele Crosmer, RD CSR https://plantbasedkidneys.com/ https://www.instagram.com/plantbased.kidneys/ Disclaimer The information provided on this channel is for educational purposes only, and does not substitute for professional medical advice. Please consult a medical professional or healthcare provider for medical advice, diagnoses, or treatment.

Studies on Endocalyx Pro effectiveness are ongoing. Several studies are complete, with more launching in the future.

Background: Mitochondrial, lysosomal, and peroxisomal dysfunction; defective autophagy; mitophagy; and pexophagy, as well as the loss of glycocalyx integrity are known contributors to initiation and progression of diverse kidney diseases. Those cellular organelles are tightly interactive in health, and during development of a disease, damage in one

Understand acute renal failure (acute kidney injury) causes, diagnosis, and treatment with this clear medical course. Medical illustrations by Dr. Seheult.

One of the hallmarks of autoimmune diabetes is the presence of adaptive responses directed to neuroendocrine proteins. One of these proteins is glutamic acid decarboxylase (GAD). While GAD is widely distributed in neuroendocrine tissues, its specific ...

Kidney Care - Kidney and Lymphatic Drainage

Presented byTHE BEST OFThe Kidney Health Docu-Class and The Metabolic Syndrome Docu-ClassA compilation of some of the most powerful moments from each docu-class — condensed into two amazing presentations for you to enjoy.Love what you're seeing?Click below to get the recordings of all 30 presentations plus access to transcripts and all the other great bonuses you see here...GET ACCESS TODAY!Own…

Muscle cramps are characterized by sudden, painful involuntary contraction of the muscles. The cramps sometimes become disabling and the prevalence is more in the elderly. The etiology of the cramps are diverse and some time the cramps are idiopathic. There are many underlying pathophysiological disorders like hypocalcemia, hypomagnesemia, hypothyroidism, and hepatorenal dysfunction which causes muscle cramp. Similarly, diabetes mellitus results in muscle cramps due to electrolytic imbalance, hypoglycemia, peripheral arterial insufficiency, and neuropathies. Persistent muscle pain in diabetic patients degrades the quality of life of those patients. Although the pathophysiology and etiology of the muscle cramp are understood to some extent, the same is less explored from diabetes mellitus perspective. Hence the objective of this review is to explore the underlying factors responsible for muscle cramps in diabetes so that proper strategy for pharmacotherapy can be made to manage this condition.

Chronic kidney disease (CKD) is a major public health concern that costs millions of lives worldwide. Natural products are consistently being explored…

Employees of Hospitals, Schools, Universities and Libraries may download FREE medical animations from Nucleus by signing up for a free trial: http://nmal.nucleusmedicalmedia.com/free-trial-membership-a #Type1Diabetes #insulin #BloodSugar MEDICAL ANIMATION TRANSCRIPT: You or someone may have been diagnosed with type 1 diabetes. This video will help you understand what it is and why it's important to keep it under control. Type 1 diabetes is a condition where your pancreas makes little or no insulin. Insulin is a chemical your body needs to keep your blood sugar at a normal level. Carbohydrates are substances your body uses to make energy. After you eat food that contains carbohydrates, it eventually goes to your small intestine. In your small intestine, the food is broken down into single sugar molecules called glucose. The cells in your small intestine soak up the sugars, which pass into your bloodstream. When the blood reaches your pancreas, it detects the high amount of sugar in your blood. Normally, this causes your pancreas to put a chemical called insulin into your bloodstream. The insulin reduces the amount of sugar in your blood to a healthy level. How does insulin do this? As the blood moves through your body, the insulin and sugar exit the bloodstream into your tissues to reach your cells. Most cells have structures on their surfaces called insulin receptors. When insulin flows by, it attaches to the receptor. The insulin acts like a key in a lock to open up the cell so the sugar can get inside. Now your cell can use the sugar to make the energy it needs to work properly, and your blood sugar level drops back to its normal range. If you have type 1 diabetes, your pancreas loses its ability to make enough or any insulin. This can result in high blood sugar levels and other complications. In type 1 diabetes, your immune system attacks some cells in your pancreas by mistake. As a result, your pancreas makes little or no insulin. Without insulin, sugar cannot get into your cells. Without sugar, your cells don't have energy. And since the sugar is locked out of your cells, it builds up to a high level in your bloodstream. This is a condition called hyperglycemia, which can lead to serious complications. If you have questions about type 1 diabetes or any medications you have been prescribed, speak with your doctor. It is important to take your medications as directed by your doctor. Tell him or her about any side effects you have. ANH16174

Cadmium (Cd) poisoning is characterized by multiple organ dysfunction in organisms, and the kidney is the main target organ of Cd toxicity. Trehalose (Tr), a multifunctional bioactive disaccharide, possesses potential kidney protective properties. Nevertheless, the specific biological function of Tr …