These findings demonstrate the health-benefit roles, including anti-oxidative and anti-proliferative activities as well as pro-apoptotic effects, of bioactive compounds in OFEs, suggesting a chemopreventive role in human cancer cells.

Altered glycosylation is a universal feature of cancer cells, and certain glycan structures are well-known markers for tumor progression. This chapter discusses some glycan biosynthetic pathways that are frequently altered in cancer cells, the correlation between altered glycosylation and clinical prognosis, the genetic basis of some of these changes, and in vitro and in vivo studies that indicate the pathological importance of these pathways.

Intestinal permeability in preterm infants represents a critical balance between absorption of nutritional agents and protection from dangerous pathogens. This study identified the relationship between feeding type (human milk and formula) and intestinal ...

http://www.ibiology.org/ibioseminars/biophysics-chemical-biology/carolyn-bertozzi-part-1.html Part 1 A large part of an organism's complexity is not encoded by its genome but results from post-translational modification. Glycosylation, or the addition of sugar molecules to a protein is an example of such a modification. These sugars, or glycans, are often complex, branched molecules specific to particular cells. Cell surface glycans determine human blood types, allow viral infections and play a key role in tissue inflammation. See more at http://www.ibioseminars.org

Glycoprotein quality control is categorized into three kinds of reactions; the folding of nascent glycoproteins, ER-associated degradation of misfolded or unassembled glycoproteins, and transport and sorting of correctly folded glycoproteins. In all three processes, N-glycans on the glycoproteins ar …

Glycoprotein quality control is categorized into three kinds of reactions; the folding of nascent glycoproteins, ER-associated degradation of misfolded or unassembled glycoproteins, and transport and sorting of correctly folded glycoproteins. In all three ...

Opuntia ficus indica, also known as prickly pads, are an important part of the human diet and are also used as forage for livestock. This is an interesting vegetable due the environmental conditions in which it grows and its resistance to climatic extremes; ...

Glycosylation is a highly sophisticated post-translational modification of proteins that occurs in the endoplasmic reticulum (ER) and the Golgi appara …

On April 10, 2015, the Canadian Glycomics Network (GlycoNet), a national network, officially launched. A celebration was held at the University of Alberta, with a program emceed by Jay Ingram, a science broadcaster and past host of Discovery Channel's Daily Planet and CBC's Quirks and Quarks. Glycomics is the study of sugars in biological processes. In this video, Jay Ingram explains the way in which glycomics is central to everyday life, and describes its potential as an emerging scientific field. For more information about GlycoNet, visit www.glyconet.ca

Four polysaccharides (named as P1, P2, and P3 from three natural Cordyceps sinensis and P4 from cultured C. sinensis) were obtained by hot-water extraction and ethanol precipitation and their structural characteristics as well as antioxidant potentials were compared. Results revealed that the backbone of P1, P2, and P3 comprised α-1,4-glucose, with a branching point mainly at position 6 and terminating at glucose. On the other hand, the structure of P4 was highly complex, mainly comprising glucose, galactose, and mannose, with 1,4-glucose and 1,4-galactose as the main chain. For in vitro antioxidant assays, all the four polysaccharides showed similar scavenging capacity against DPPH and hydroxyl radicals, whereas P1 had a relatively low ferric reducing ability, possibly related to a combination of factors such as the phenolic compounds and amino acids that conjugated in polysaccharides.

camera & edit: http://www.levroi.nl | event information www.TEDxRoermond.nl "These sugars are the missing link in our food and maybe even the missing link in our medicine." Geiske de Ruig explains us about a new science: Glycobiology, the science of sugars. You musn't confuse these essential sugars with the sugars you put in your coffee or tea. These essential sugars are important for cells to communication with each other. Geiske even advocates the relation of our modern diet and shortage of sugars with the rapid growth of health issues. She will convince you to take control over your own health by adjusting your diet. Everyone can start today! About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.

camera & edit: http://www.levroi.nl | event information www.TEDxRoermond.nl "These sugars are the missing link in our food and maybe even the missing link in our medicine." Geiske de Ruig explains us about a new science: Glycobiology, the science of sugars. You musn't confuse these essential sugars with the sugars you put in your coffee or tea. These essential sugars are important for cells to communication with each other. Geiske even advocates the relation of our modern diet and shortage of sugars with the rapid growth of health issues. She will convince you to take control over your own health by adjusting your diet. Everyone can start today! About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.

Abstract. The glycosylation profile of a recombinant protein is important because glycan moieties can play a significant role in the biological properties of th

Can gut bugs change the world? Join Warren Peters on a journey into understanding your microbiome and the new discoveries changing the way we understand diabetes, obesity, Alzheimer's disease, autism, and our everyday health and wellness. If asked, he will tell you that the first part of his medical career was in general surgery, where “if something is wrong with you, I will cut it out." The next was dedicated to lifestyle and natural medicines, where “if something is wrong with you, just try harder." And finally, the last part is dedicated to the molecular and genetic basis of obesity, where "if something is wrong with you, it is the fault of your parents and the changing environment." Within these three perspectives, reside the virtues of common sense and wisdom. He obtained his medical degree from Loma Linda University, his surgical training at the Mason Clinic in Seattle Washington, and, his Master’s degree in biostatistics and epidemiology from Loma Linda University. He is privileged to travel and lecture nationally and internationally on topics of nutrition, wholeness, and wellness. He has practiced surgical care, wholistic care, and, primary care in Washington, Maryland, Virginia, and California. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx

Do Artificial Sweeteners Cause Thyroid Disease? There is a big debate raging on about the detrimental dangers of artificial sweeteners like sucralose. Recent research shows that using excessive sucralose (AKA - Splenda) can cause Hashimoto's disease. Animal studies have also shown that sucralose (chlorinated sugar) can disrupt the thyroid axis. If you have Hashimoto's disease, you might want to consider avoiding foods and other products containing sucralose. To connect with Dr. Osborne visit: Facebook: https://www.facebook.com/DoctorPeterO... Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.

The glycocalyx of the endothelium is an intravascular compartment that creates a barrier between circulating blood and the vessel wall. The glycocalyx is suggested to play an important role in numerous physiological processes including the regulation of vascular permeability, the prevention of the margination of blood cells to the vessel wall, and the transmission of shear stress. Various theoretical models and experimental approaches provide data about changes to the structure and functions of the glycocalyx under various types of inflammatory conditions. These alterations are suggested to promote inflammatory processes in vessels and contribute to the pathogenesis of number of diseases. In this review we summarize current knowledge about the modulation of the glycocalyx under inflammatory conditions and the consequences for the course of inflammation in vessels. The structure and functions of endothelial glycocalyx are briefly discussed in the context of methodological approaches regarding the determination of endothelial glycocalyx and the uncertainty and challenges involved in glycocalyx structure determination. In addition, the modulation of glycocalyx structure under inflammatory conditions and the possible consequences for pathogenesis of selected diseases and medical conditions (in particular, diabetes, atherosclerosis, ischemia/reperfusion, and sepsis) are summarized. Finally, therapeutic strategies to ameliorate glycocalyx dysfunction suggested by various authors are discussed.