Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction
Trehalose (TRE) is a natural, nonreducing disaccharide synthesized by lower organisms. TRE exhibits an extraordinary ability to protect cells against …
Trehalose
Trehalose-Induced Structural Transition Accelerates Aggregation of a-S (...)
Fibrillation of α-synuclein proceeds through distinct stages, with oligomers combining to form the seed or the nucleus, followed by exponential and saturation phases. Osmolytes are considered to act as protein stabilizers by virtue of their ability to inhibit protein aggregation. Trehalose, a non-re …
Trehalose-Induced Structural Transition Accelerates Aggregation of a-Synuclein. - PubMed - NCBI
Fibrillation of α-synuclein proceeds through distinct stages, with oligomers combining to form the seed or the nucleus, followed by exponential and saturation phases. Osmolytes are considered to act as protein stabilizers by virtue of their ability to inhibit protein aggregation. Trehalose, a non-re …
Trehalose-mediated autophagy impairs the anti-viral function of human (...)
Human rhinovirus (HRV) is the most common cause of acute exacerbations of chronic lung diseases including asthma. Impaired anti-viral IFN-λ1 production and increased HRV replication in human asthmatic airway epithelial cells may be one of the underlying mechanisms leading to asthma exacerbations. In …
trehalose[Title] human[Title] - PubMed - NCBI
Variable Effects of Autophagy Induction by Trehalose on Herpesviruses (...)
Trehalose is a non-reducing sugar formed from two glucose units. Trehalose induces abundant autophagy in cultured cells and also reduces the rate of aggregation of the huntingtin protein in the animal model of Huntington disease, a chronic neurological disease in humans. The mechanism of this effect …