🗽 10.3 - Cultural

🗽 10.3 - Cultural

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The primate gut microbiota contributes to interspecific differences in host metabolism
The primate gut microbiota contributes to interspecific differences in host metabolism
Because large brains are energetically expensive, they are associated with metabolic traits that facilitate energy availability across vertebrates. However, the biological underpinnings driving these traits are not known. Given its role in regulating host metabolism in disease studies, we hypothesized that the gut microbiome contributes to variation in normal cross-vertebrate species differences in metabolism, including those associated with the brain’s energetic requirements. By inoculating germ-free mice with the gut microbiota (GM) of three primate species – two with relatively larger brains and one with a smaller brain – we demonstrated that the GM of larger-brained primates shifts host metabolism towards energy use and production, while that of smaller-brained primates stimulates energy storage in adipose tissues. Our findings establish a causal role of the GM in normal cross-host species differences in metabolism associated with relative brain size and suggest that the GM may have been an important facilitator of metabolic changes during human evolution that supported encephalization.
·microbiologyresearch.org·
The primate gut microbiota contributes to interspecific differences in host metabolism
School Dashboard | Notion Everything
School Dashboard | Notion Everything
A simple school dashboard template with a stellar twist! I created this template to keep track of my courses, notes, and assignments — and to plan out future courses for my degree.
·notioneverything.com·
School Dashboard | Notion Everything
Popular University of Social Movements (UPMS)
Popular University of Social Movements (UPMS)
The Popular University of Social Movements (UPMS) was created within the World Social Forum (WSF) in 2003, with the aim of promoting shared knowledge and extending, linking and strengthening forms of resistance to neoliberal globalisation, ...
·alice.ces.uc.pt·
Popular University of Social Movements (UPMS)