Health

Pudendal neuralgia caused by pudendal nerve entrapment (PNE) is a chronic and often severely disabling neuropathic pain syndrome.[1] It presents in the sensory distribution region of the pudendal nerve and affects both males and females. The most characteristic symptom, found in over 50% of patients, is perineal pain exacerbated by sitting, which is relieved by standing or lying.[2] It is frequently misdiagnosed or underdiagnosed and inappropriately treated, initially causing a significant delay in proper management and severely negatively impacting the quality of life.

[Possibly contact about possible use of turmeric to treat malaria]

Apply for and manage the VA benefits and services you’ve earned as a Veteran, Servicemember, or family member—like health care, disability, education, and more.

Parkinson’s disease (PD) is the most common movement disorder in the world, affecting 1–2 per 1,000 of the population. The main pathological changes of PD are damage of dopaminergic neurons in substantia nigra of the central nervous system and ...

Parkinson's Disease is a debilitating illness with no known cure. Learn how pig cells could be used to slow Parkinson's on our blog.

Central nervous system (CNS) depressants used to manage symptoms of psychosis and anxiety disorders include antipsychotics and anxiolytics, which may cause psychosis. Antipsychotics are also…

Join your host, Nicole Morris, LMFT and Mental Health Correspondent, for Part V of our 3rd Annual OCRD Series to chat about Obsessive Compulsive Personality ...

This workshop is for anyone who feels life is taking place at a distance. We will work directly on the experiences of dissociation and numbness.

When people think of Botox®, most think of cosmetic or plastic surgery. But Botox injections can be used to treat urinary incontinence and overactive bladder symptoms, too. Are injections right for you?

Abstract This chapter describes primary and secondary bone tumors affecting the skull base and provides important epidemiologic and imaging clues for the differential diagnosis. Except for bone met…

We heal at the rate that we safe to.

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Aripiprazole is a novel antipsychotic medication that is used to treat a number of psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder. Although not specifically indicated for this, novel antipsychotics ...

Fenbendazole is a benzimidazole anthelmintic agent commonly used to treat animal parasitic infections. In humans, other benzimidazoles, such as mebendazole and albendazole, are used as antiparasitic agents. Since fenbendazole is not currently approved by the FDA or EMA, its pharmacokinetics and safety in humans have yet to be well-documented in medical literature. Despite this, insights can be drawn from existing in vitro and in vivo animal studies on its pharmacokinetics. Given the low cost of fenbendazole, its high safety profile, accessibility, and unique anti-proliferative activities, fenbendazole would be the preferred benzimidazole compound to treat cancer. To ensure patient safety in the repurposing use of fenbendazole, it is crucial to perform clinical trials to assess its potential anticancer effects, optimal doses, therapeutic regimen, and tolerance profiles. This review focuses on the pharmacokinetics of orally administered fenbendazole and its promising anticancer biological activities, such as inhibiting glycolysis, down-regulating glucose uptake, inducing oxidative stress, and enhancing apoptosis in published experimental studies. Additionally, we evaluated the toxicity profile of fenbendazole and discussed possibilities for improving the bioavailability of the drug, enhancing its efficacy, and reducing potential toxicity.

ARIPiprazole and losartan may have additive effects in lowering your blood pressure.

!!!! Contraindicated in renal insufficiency (serum creatinine 1.5 mg/dL in men or abnormal creatinine clearance

Cholinesterase inhibitors are drugs that prevent the breakdown of acetylcholine, and blocks the action of acetylcholinesterase in the body. Researchers believe that decreased levels of acetylcholine in the brain causes Alzheimer's disease symptoms. Common side effects of cholinesterase inhibitors are insomnia, abnormal dreams, weight loss, headache, nausea, vomiting, diarrhea, confusion, and fatigue.

Compare cholinesterase inhibitors (acetylcholinesterase inhibitors). View important safety information, ratings, user reviews, popularity and more.

~Venlafaxine and ODV have no significant affinity for muscarinic, ~Aggression may occur in some patients who have received antidepressants, including venlafaxine treatment, dose reduction, or discontinuation ~aggression have been observed in patients during changes in venlafaxine dosing regimen, including during discontinuation ~Discontinuation.. symptoms include aggression, agitation,

Chemical

Cholinergic transmission at muscarinic acetylcholine receptors (mAChR) has been implicated in higher brain functions such as learning and memory, and loss of synapses may contribute to the symptoms of Alzheimer disease. A heterogeneous family of ...

Cognitive impairment is a core symptom of schizophrenia and a major determinant of poor long-term functional outcomes. Despite considerable efforts, we do not yet have any approved pharmacological treatments for cognitive impairment associated with ...