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The combination of low-dose trospium and solifenacin provides good clinical and urodynamic effects in elderly patients with moderate symptoms of OAB. Combination of these drugs in standard doses for such patients is excessive.

This research is aimed to study the possibility of management of severe symptoms of overactive bladder (OAB) with solifenacin and trospium in patients who receive treatment with tamsulosin due to benign prostatic hyperplasia (BPH). The 338 men more than 50 years old (average age 58.4 years) diagnose …

Understanding the biology of overeating makes it easier to come up with a sustainable overeaters anonymous food plan. Take a look...

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View photos of wet and dry macular degeneration and videos about AMD and your eyes. These pictures of retinas - called fundus photographs - show the different effects of wet and dry macular degenerati

Taurine is an organic osmolyte involved in cell volume regulation, and provides a substrate for the formation of bile salts. It plays a role in the modulation of intracellular free calcium concentration, and although it is one of the few amino acids not ...

If you're fighting a painful toothache, check out these 29 easy, low-maintenance DIY at-home remedies to try while you wait to see the dentist.

Wheatgrass is all the rage these days. This article examines 7 benefits of wheatgrass that are backed by science.

use of zinc lozenges at doses of over 75 mg/day reduced the duration of the common cold

Are you exhausted, experiencing fuzzy thinking and suffering from muscle weakness/joint pain? We cover common candida symptoms and a natural treatment plan.

The sinuvertebral nerve, also known as the recurrent meningeal nerve, or the recurrent nerve of Luschka, is a branch of the primary ventral ramus and grey ramus communicans in the intervertebral foramen. It enters the spinal canal and supplies th...

This article is a review and evaluation of the world literature on the systemic use of procaine in the treatment of the aging process and the common chronic diseases of later life. Included are data from 285 articles and books, describing treatment in more than 100,000 patients in the past 25 years. …

If you're concerned about neovascular glaucoma, find out everything you need to know about this serious eye condition.

Proliferative diabetic retinopathy is a late-stage complication of diabetes-related eye disease. How to prevent progression to avoid vision loss.

Pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) represent a spectrum of the same disease characterized by excessive pigment liberation throughout the anterior segment of the eye. The classic triad consists of dense trabecular meshwork pigmentation, mid-peripheral iris transillumination defects, and pigment deposition on the posterior surface of the central cornea. Pigment accumulation in the trabecular meshwork reduces aqueous outflow facility and may result in elevation of intraocular pressure (IOP), as seen in pigment dispersion syndrome, or in optic nerve damage associated with visual field loss, as seen in pigmentary glaucoma. Pigmentary glaucoma and PDS occur when pigment is released from the iris pigment epithelium due to rubbing of the posterior iris against the anterior lens zonules. The disease is more prevalent in males, and typically presents in the 3rd-4th decade of life.

Overactive bladder (OAB) syndrome is a chronic medical condition which has a major influence on the quality of life in a significant amount of the population. OAB affects performance of daily activities and has an estimated prevalence of 16.5%. Many sufferers ...

Aims: We examined the relative efficacy and safety of trospium 20 mg bid and 60 mg extended release formulations and position this drug against other antimuscarinic agents. Methods: Data were ident...

Clinical characteristics of anticholinergic toxicity include anhidrosis, anhidrotic hyperthermia, vasodilation-induced flushing, mydriasis, urinary retention, and neurological symptoms, including delirium, agitation, and hallucinations. The memory aid “red as a beet, dry as a bone, blind as a bat, mad as a hatter, hot as a hare, full as a flask’ often serves as means of remembering the common symptoms of anticholinergic toxicity

proven ocular side effects from oral ingestion of these anticholinergics, the prescribing physician should be notified by the managing eye care provider.. patients with decreased hepatic and/or renal function may be at higher risk of overdose or of experiencing side effects than patients with normal hepatic and/or renal function.7 Interestingly, co-administration of medications that can inhibit the P-450 enzymes in the liver responsible for metabolizing a variety of substances and medications can lead to a build-up of toxic by-products of anticholinergic OBS medications.7 Specifically, medications like buproprion, fluoxetine, paroxetine, terbinafine, quinidine, cimetidine, ritonavir, ketoconazole, itraconazole, verapamil, cyclosporine, erythro- mycin, clarithromycin, and fluconazole, and even grapefruit juice, can lead to a faster build- up of toxic levels of OBS anticholinergics.7

Narcissistic traits can make it difficult to have healthy relationships. Here, learn how to stop being a narcissist so you can improve your relationships.