The link between the gut microbiome and autism is not backed by science, researchers say
There's no scientific evidence that the gut microbiome causes autism, a group of scientists argue in an opinion paper published in Neuron. They point to the fact that conclusions from past research that supported this hypothesis—including observational studies, mouse models of autism, and human clinical trials—are undermined by flawed assumptions, small sample sizes, and inappropriate statistical methods.
A new opinion paper shows no convincing evidence that there is a causal link between gut bacteria and autism, citing weak research and hype that sustained an unproven theory.
Predictors of Depression and Anxiety Among Self-Medicating Autistic Adults - Chris Papadopoulos, Tanya Adkin, Katie Munday, David Gray-Hammond, 2025
Background: We aimed to investigate self-medication prevalence, mental health problems, and their relationship among autistic adults. We also sought to identify...
Would A New Diagnosis Of Profound Autism Help Autistic People?
The autism community finds itself divided over whether creating a 'profound autism’ subtype would help those with the greatest needs, or leave them even more vulnerable.
Medscape: Memantine Boosts Social Functioning in Some Autism Cases
A small trial shows behavioral gains with memantine in a subset of youth with autism. While promising, researchers are quick to note that more research is needed.
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Medscape: The Complex Origins of Autism: What the Science Shows
Clinicians and researchers continue to push back on unsupported claims about the causes of autism while new NIH projects aim to clarify its complex origins.
Medscape: Autism Is Not One Disorder, New Data Show
Autism diagnosed early differs genetically and developmentally from autism identified later, challenging the theory that it is a single, uniform condition.
Why it's time to rethink the notion of an autism 'spectrum'
The phrases "autism spectrum" or "on the spectrum" have become part of everyday language. They are often used as different ways of referring to someone who is "neurodivergent."
Should the Autism Spectrum Be Split Apart? Families of people with severe autism say the repeated expansion of the diagnosis pushed them to the sidelines. A new focus on the disorder has opened the way for them to argue their cause. : r/sciences
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Medscape: Explainer-Why Is Leucovorin Being Considered as an Autism Treatment?
On Monday, the U.S. Food and Drug Administration published a notice to the Federal Register ahead of a speech by President Donald Trump, approving a version of leucovorin...
Are You Performing Normal? The Hidden Cost of Masking in Adulthood | Embrace Autism
Conscious attention to how you interact in order to be accepted is known as masking. It involves blending in, smoothing edges, hiding instincts, doing things you really don't want to and sometimes a full acting job. It is no wonder so many autistics are real-life actors.
Could it be autism? Why adult autistics aren’t always recognized | Embrace Autism
For many autistic people—especially those without intellectual disability—autism doesn’t look like what most people expect. You might have done well in school. You might have a job, a family, and a rich internal world. And still, something doesn’t quite fit. Behind the scenes there is a constant hum of effort: interpreting social cues, replaying conversations, preparing scripts for interactions that others seem to do with ease. In reality autistics are doing a lot of work: the quiet act of holding back a stim, copying someone’s smile, or adjusting tone mid-sentence to sound “just right.” Over time, these adjustments shape how others see you: competent, agreeable, even charismatic. But they also erode your energy, your clarity, your sense of self.
New Autism Research Reveals 4 Genetic Types - Which One Are You?
Hi! I'm Orion Kelly and I'm Autistic. A groundbreaking new study, “Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs” (...
Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs | Nature Genetics
Classes of autism are uncovered with a generative mixture modeling approach leveraging matched phenotypic and genetic data from a large cohort, revealing different genetic programs underlying their phenotypic and clinical traits.