2016

seaweed Laminaria japonica (LJP) is a traditional medicine and food in Asia that has shown pharmacological and biochemical properties favorable to the prevention and treatment of lifestyle-related diseases. We will systematically review randomized controlled trials and in vivo preclinical studies evaluating the efficacy and safety of LJP as a useful treatment for metabolic syndrome. Methods: The following databases will be searched from inception to September 2021: MEDLINE (via PubMed), EMBASE, Cochrane Central Register of Controlled Trials, and Web of Science. Randomized controlled trials and in vivo preclinical studies that analyzed LJP for the prevention and treatment of metabolic syndromes will be included. The outcome measures will include body composition, dietary habit scores, serum lipid profiles, daily nutrient intake, quality of life, number of microbiomes, gastrointestinal symptoms, and bowel function. Studies comparing LJP with any type of control intervention will be included. Data extraction using Review Manager version 5.3 and risk of bias assessment using the Cochrane Collaboration's tool for assessing risk of bias will be performed by 2 independent assessors. Results and Conclusion: This systematic review will provide evidence confirming the efficacy and safety of LJP in the treatment of metabolic syndrome. Ethics and dissemination: Ethical approval was not required, as this study protocol does not include any personal information of the participants. Trial registration number: DOI 10.17605/OSF.IO/G2BQK (https://osf.io/g2bqk)....

Stop "the Silent Killer" Dead in Its Tracks!Where should we send your FREE eBook? function submitWebForm() { var form = document.forms[0]; var resolution = document.createElement('input'); resolution.setAttribute('id', 'screenResolution'); resolution.setAttribute('type', 'hidden'); resolution.setAttribute('name', 'screenResolution'); var resolutionString = screen.width + 'x' + screen.height; resolution.setAttribute('value', resolutionString); form.appendChild(resolution); var pluginString = ''; if (window.ActiveXObject) { var activeXNames = {'AcroPDF.PDF':'Adobe Reader', 'ShockwaveFlash.ShockwaveFlash':'Flash', 'QuickTime.QuickTime':'Quick Time', 'SWCtl':'Shockwave', 'WMPLayer.OCX':'Windows Media…

(NaturalHealth365) Pain pills are narcotics, meant to provide pain relief. But, before you take these drugs, find out their downside.

Spike Proteins In Immune Cells - Dr. Bruce Patterson Discusses COVID Long Haul Dr. Bruce Patterson’s team has discovered that the S1 pieces of the spike proteins persist in the monocytes resulting in immune dysregulation and long-haul syndrome. Let’s discuss these findings with him. Dr. Patterson’s site: https://covidlonghaulers.com/ Disclosure: Dr. Mobeen Syed, or DrBeen have no commercial interest with Dr. Bruce Patterson’s organization. Want to support this work to get a balanced take on the medical sciences? Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true Looking to support my educational work? Donate here: https://paypal.me/mobeensyed?locale.x=en_US Join us on Discord: https://discord.gg/bkmg3rk3sQ Claim your #koolbeen title here: https://www.drbeen.com/koolbeen-title-registry/ #drbeen #koolbeens #COVID

Pericarditis after vaccination, possible inadvertent intravenous administration. Useful links as discussed in this video, https://www.react19.org/ https://www.youtube.com/watch?v=aebtcTi7EaA https://www.youtube.com/channel/UC4eegkSVzV56kTrSpvL6BKQ Rally in DC next month https://www.realnotrare.com Messages from Kyle Also a lot of people have been asking about my supplements and Ivermectin. Here are some good studies on the benefits. Ivermectin - https://pubmed.ncbi.nlm.nih.gov/32871846/ Star Anise / Flavonoids - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271800/

Update: Heart Failure Is On The Rise ...Discover How to Strengthen Your Heart and Avoid This ConditionWhere should we send your FREE eBook? function submitWebForm() { var form = document.forms[0]; var resolution = document.createElement('input'); resolution.setAttribute('id', 'screenResolution'); resolution.setAttribute('type', 'hidden'); resolution.setAttribute('name', 'screenResolution'); var resolutionString = screen.width + 'x' + screen.height; resolution.setAttribute('value', resolutionString); form.appendChild(resolution); var pluginString = ''; if (window.ActiveXObject) { var activeXNames…

A former clinical trial overseer for a contractor holding trials of Pfizer’s COVID-19 vaccine is pressing forward with a lawsuit against Pfizer and her former company

(NaturalHealth365) Why has China not administered mRNA shots to its citizens? Do they know something that the rest of the world does not?

Blood clots have emerged as the common factor unifying many of the symptoms of COVID-19. Researchers in Germany have discovered that the virus changes the size and stiffness of red and white blood cells in the human body. Moreover, these changes can last for months, possibly explaining the seemingly never-ending symptoms of COVID-19. In December of... View Article

TruNews is the world's leading news source that reports, analyzes, and comments on global events and trends with a conservative, orthodox Christian worldview.

Todd Callender (Disabled Rights Advocates Lawyer) - Gene Therapy Creates New Human Species - The John-Henry Westen Show https://ugetube.com/watch/todd-callender-disabled-rights-advocates-lawyer-gene-therapy-creates-new-human-species-the-john-henr_K…

The present work aimed to explore the effect and underlying mechanism of a homogeneous Laminaria japonica polysaccharide (LJP61A) on macrophage polarization in high-fat-diet-fed LDLr–/– mice and Ox-LDL-induced macrophages. Results showed that LJP61A remarkably reduced the lesion burden in atherosclerotic mice, alleviated lipid deposition in Ox-LDL-stimulated macrophages, decreased the expression of M1 macrophage markers, and increased the expression of M2 macrophage markers, thus reducing the M1/M2 macrophage phenotype ratio. Meanwhile, the autophagic flux of macrophages was enhanced by LJP61A treatment in vitro and in vivo. 3-Methyladenine is an autophagic inhibitor. As expected, this inhibitor blocked the effects of LJP61A on macrophage polarization. SIRT1 and FoxO1 are two key upstream genes that control the autophagy behavior. We also found that LJP61A significantly up-regulated the expression of SIRT1 and FoxO1. However, these effects of LJP61A were abolished by the SIRT1 siRNA and FoxO1 inhibitor AS1842856. These results suggested that LJP61A reduced atherosclerosis in HFD-induced LDLr–/– mice via regulating autophagy-mediated macrophage polarization.