2016

Want better sleep, faster recovery, and peak performance? In this powerful episode of The Dr. Hyman Show, Dr. Mark Hyman sits down with human performance exp...

This short video was created in May of 2024. The things Gary Stearman and Bill Salus discussed concerning the current events in Iran at that time, we are sti...

#Parkinsons #TheParkinsonsPlan #EnvironmentalHealth #Neuroscience #PreventParkinsonsParkinson’s disease is rising faster than ever before — with 90,000 new U...

Low molecular weight fucoidan (LMWF), a depolymerized form, is known to possess superior bioactivities compared to its high molecular weight counterpa…

2nd-generation muffler, exhaust & auto repair and service shops in Boise & Garden City. High expertise, great value & top customer service.

The data that shows the less appreciated and forgotten consequences of vaccination.

Link to the notes:  https://docs.google.com/document/d/1G0JYEOi1HyTzyT3RxAX8AbIZejyZyl_s/edit?usp=drivesdk&ouid=102430545303799711405&rtpof=true&sd=true C04-5-18

Ozempic works… until it doesn’t. Then your real problems begin.

The Immense Dangers of the GLP-1 drugs and the Scandalous Corruption That Led the FDA to Push Them Upon America

Henry B. Smith Jr. of Associates for Biblical Research is the guest on Let Us Reason and discusses the numerical divergences between the Masoretic Text, Sama...

(NaturalHealth365) Forever chemicals in pregnancy program children for teen hypertension. Learn how to protect your family.

Ulcerative colitis (UC), a chronic inflammatory bowel disease driven by gut dysbiosis, immune dysregulation, and oxidative stress, lacks universally effectiv...

This study investigates the anti-lung cancer activities of polysaccharides extracted from Laminaria japonica, focusing on their bioactive components a…

About 2600 years ago, the prophet Jeremiah predicted that in the latter days a disaster would happen in ELAM, which is in modern day SW IRAN. The details of ...

Israel is at the center of the End Times. So Jewish End Time beliefs influence what happens NEXT. And they are NOT what you EXPECT. They will impact how Jew...

Clean, speed up, and protect your PC with Spyzooka. Remove spyware, fix errors, and optimize performance—fast, easy, and effective!

Ezekiel 38 is a marquee prophetic event of the end times. Many of today's top experts think it could be the next prophecy to find fulfillment. But are they c...

Glioblastoma presents significant challenges in neuro-oncology due to its aggressive nature, drug resistance, and restrictions imposed by the blood–brain barrier. Ivermectin (IVM), known for its antiparasitic properties, has been highlighted as a promising treatment for tumors and an alternative therapy for glioma, although it exhibits low oral bioavailability. Therefore, we investigated the in vivo effect of IVM encapsulation in organic and inorganic nanosystems, first screened in vitro against different tumor cells and subsequently evaluated in vitro and in vivo glioma models. We produced IVM-loaded poly(ε-caprolactone) nanocapsules (IVM-NC) using the interfacial deposition method, and IVM-loaded nanostructured silica particles (IVM-MCM) by loading IVM into commercial MCM-41 silica using the incipient wetness method. IVM-NC had a nanometric size (190 nm), a unimodal size distribution (span <2), and a high encapsulation efficiency (100% at 1 mg/mL). IVM-MCM exhibited a well-organized hexagonal mesoporous structure and high drug loading (0.12 mg/mg). Nanoencapsulated IVM significantly reduced the viability of various cancer cell lines, particularly glioma cell lines, which led us to evaluate them in a preclinical glioma model. We implanted adult male Wistar rats with C6 cells. Intranasal delivery of IVM-NC (60 μg/rat/day for 10 days) resulted in a larger decrease in tumor size compared with the group treated with free IVM, along with histopathological improvements. Treatment with IVM-MCM did not decrease the tumor size. However, both treatments were well-tolerated, with no adverse effects on weight, biochemical, or hematological parameters, or lung histology. Furthermore, the effective equivalent dose of IVM (26 μg/kg) in the rat glioma model was lower than the approved human dose for parasitic infections. This study marks the first exploration of IVM delivery to the brain. In summary, nasal administration of nanoencapsulated IVM via nanocapsules presents a promising avenue for targeted therapy against glioblastoma, with potential implications for clinical translation.

We are pleased to announce that the first-of-its-kind protocol utilizing Ivermectin, Mebendazole, and Fenbendazole for cancer treatment has ...

. Introduction Many theories exist regarding the origin of cancer, namely the metabolic theory (Seyfried & Chinopoulos, 2021), the somatic mutation theory (SMT) (Hanahan & Weinberg, 2000), the cancer stem cell theory (Capp, 2019), and the tissue organization theory (Soto & Sonnenschein, 2011). In a recently published study, a new concept was introduced the

In this video, Dr. Nathan Bryan explains a detoxification protocol designed to target chronic diseases driven by nutrient deficiencies and toxin exposure. Th...

Exposing the pain industry and the forgotten treatments for pain

Share This Sign up at: ParkinsonsDisease.blog About Jonathan Sackner-Bernstein, MD Dr. Sackner-Bernstein shares his pursuit of conquering Parkinson's, using expertise developed as Columbia University faculty, FDA senior official, DARPA insider and witness to the toll of PD. Dr. S-B’s Linkedin page RightBrainBio, Inc. was incorporated in 2022 to develop tranformative therapies for people with Parkinson's.

Dwayne “The Rock” Johnson discusses his health journey —and the test results that pushed him to take more control of his health.In this powerful episode of T...

Ron Wyatt's discovery of Sodom and Gomorrah is miraculous- the evidence was hidden until just the right time! the remains are spectacular to view and the mes...

(NaturalHealth365) Genetic lottery determines if common chemo drugs save or kill you, but doctors rarely test before treatment starts.

Background Chronic kidney disease (CKD) poses significant health challenges worldwide, with limited effective natural therapies targeting its progression through antioxidant mechanisms. Although gum acacia (GA) has shown general metabolic benefits, its dose-dependent therapeutic efficacy in CKD and its effects on key antioxidant pathways remain unclear. This study aimed to evaluate the therapeutic potential of gum acacia (GA) in an adenine (AD)-induced CKD rat model. Methods Rats were randomly assigned to five groups (n = 7 per group): Group I (control), Group II (GA at 600 mg/kg for 14 days), Group III (AD at 600 mg/kg for 10 days), and Groups IV and V (AD for 10 days followed by GA at 300 mg/kg or 600 mg/kg for 14 days). All treatments were administered daily by oral gavage. Results AD treatment led to significant reductions in body weight, increased relative kidney weight, and disrupted kidney and liver function markers, including elevated urea, creatinine, ALT, GGT, and glucose levels. AD also increased oxidative stress, altered blood parameters, and caused downregulation of APRT mRNA expression and upregulation of FGF-23 expression. GA treatment at both doses (300 and 600 mg/kg) mitigated these abnormalities, significantly improving kidney and liver function, enhancing antioxidant status, and ameliorating hematological and metabolic disturbances. The most pronounced effects were observed with the 600 mg/kg dose. Conclusions Building on prior indications of GA’s benefits, our findings offer new and comprehensive evidence of its dose-dependent therapeutic effects in adenine-induced CKD, particularly through the modulation of oxidative stress pathways and regulation of APRT and FGF-23 expression. These insights lay the groundwork for future clinical translation.

Fucoidans have demonstrated a wide range of bioactivities including immune modulation and benefits in gut health. To gain a deeper understanding on the effects of fucoidan from Undaria pinnatifida (UPF) on the colonic microbiome, the short-term Simulator of the Human Intestinal Microbial Ecosystem®, a validated in vitro gut model, was applied. Following a three-week intervention period on adult faecal samples from three healthy donors, microbial community activity of the colonic microbiota was assessed by quantifying short-chain fatty acids while composition was analysed utilising 16S-targeted Illumina sequencing. Metagenomic data were used to describe changes in community structure. To assess the secretion of cytokines, co-culture experiments using Caco-2 and THP1-Blue™ cells were performed. UPF supplementation over a three-week period had a profound butyrogenic effect while also enriching colonic microbial diversity, consistently stimulating saccharolytic genera, and reducing genera linked with potentially negative health effects in both regions of the colon. Mild immune modulatory effects of UPF were also observed. Colonic fermentation of UPF showed anti-inflammatory properties by inducing the secretion of the anti-inflammatory cytokines IL-6 and IL-10 in two out of three donors in the proximal and distal colon. In conclusion, UPF supplementation may provide significant gut health benefits.

This culture that came BEFORE the Native Americans is ASTONISHING. In this video, Dr. Nathaniel Jeanson uncovers some surprising archaeological discoveries h...