Fucoidan alleviates the inhibition of protein digestion by chitosan and its oligosaccharides - ScienceDirect
Chitosan (CTS) and chitosan oligosaccharides (COS) have been widely applied in food industry due to their bioactivities and functions. However, CTS an…
Effects of UV/H2O2 Degradation on the Physicochemical and Antibacterial Properties of Fucoidan
The applications of fucoidan in the food industry were limited due to its high molecular weight and low solubility. Moderate degradation was required to depolymerize fucoidan. A few studies have reported that fucoidan has potential antibacterial activity, but its antibacterial mechanism needs further investigation. In this study, the degraded fucoidans were obtained after ultraviolet/hydrogen peroxide treatment (UV/H2O2) at different times. Their physicochemical properties and antibacterial activities against Staphylococcus aureus and Escherichia coli were investigated. The results showed that the average molecular weights of degraded fucoidans were significantly decreased (up to 22.04 times). They were mainly composed of fucose, galactose, and some glucuronic acid. Fucoidan degraded for 90 min (DFuc-90) showed the strongest antibacterial activities against Staphylococcus aureus and Escherichia coli, with inhibition zones of 27.70 + 0.84 mm and 9.25 + 0.61 mm, respectively. The minimum inhibitory concentrations (MIC) were 8 mg/mL and 4 mg/mL, respectively. DFuc-90 could inhibit the bacteria by damaging the cell wall, accumulating intracellular reactive oxygen species, reducing adenosine triphosphate synthesis, and inhibiting bacterial metabolic activity. Therefore, UV/H2O2 treatment could effectively degrade fucoidan and enhance its antibacterial activity.
My Results After Trying 10 Peripheral Neuropathy Treatments - YouTube
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This Fall's EXPLODING Nova Sign of the Rise of Antichrist? Peace Covenant Coming? - YouTube
This fall a NOVA will Explode and form a new star in the middle of the sign of the Dragon from Revelation 12:3. How is this extra star a sign of the rise of ...
Exposing Ukraine’s Secret Police and Mission to Exterminate Christianity
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! 1 Laetrile The Dr Ardis Show | Interview with Richardson Nutritional Center | 04.22.2024
Watch as Dr Ardis interviews the President of Richardson Nutritional Center President, John A. Richardson, Jr. about the power of Laetrile and the legacy of his father, Dr. John A. Richardson, MD, who
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With monumental events unfolding before our eyes and the attack of Iran on Israel, are we watching ancient prophecies being fulfilled? Are these part of God...
Recent updates in the treatment of diabetic polyneuropathy - PMC
Distal symmetric diabetic peripheral polyneuropathy (DPN) is the most common form of neuropathy in the world, affecting 30 to 50% of diabetic individuals and resulting in significant morbidity and socioeconomic costs. This review summarizes updates in ...
What is celiac disease and how does it cause nerve damage? Learn more: https://winsantor.com/nerve-damage-and-celiac-disease-the-hidden-connection/Visit our ...
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Do you suffer from diabetic neuropathy, chemo-induced neuropathy, or HIV neuropathy? Join our clinical trials. Subscribe for updates and information on clinical trials.
! 1 Exciting Developments in the Treatment of Peripheral Neuropathy | Dr. Fernyhough & Dr. Calcutt - YouTube
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The Third Temple is Already Here (But People Don’t See It) - YouTube
Order _The Temple Revealed_ by Dr. Christian Widener here: https://amzn.to/3IZH3tmUncover The Prophetic Secret To Unraveling 3000 Years Of Temple Mount Histo...
Fucoidan Improves Early Stage Diabetic Nephropathy via the Gut Microbiota–Mitochondria Axis in High-Fat Diet-Induced Diabetic Mice | Journal of Agricultural and Food Chemistry
Diabetic nephropathy (DN) is a common microvascular complication of diabetes. Fucoidan, a polysaccharide containing fucose and sulfate group, ameliorates DN. However, the underlying mechanism has not been fully understood. This study aimed to explore the effects and mechanism of fucoidan on DN in high-fat diet-induced diabetic mice. A total of 90 C57BL/6J mice were randomly assigned to six groups (n = 15) as follows: normal control (NC), diabetes mellitus (DM), metformin (MTF), low-dose fucoidan (LFC), medium-dose fucoidan (MFC), and high-dose fucoidan (HFC). A technique based on fluorescein isothiocyanate (FITC-sinistin) elimination kinetics measured percutaneously was applied to determine the glomerular filtration rate (GFR). After 24 weeks, the mice were sacrificed and an early stage DN model was confirmed by GFR hyperfiltration, elevated urinary creatinine, normal urinary albumin, tubulointerstitial fibrosis, and glomerular hypertrophy. Fucoidan significantly improved the GFR hyperfiltration and renal fibrosis. An enriched SCFAs-producing bacteria and increased acetic concentration in cecum contents were found in fucoidan groups, as well as increased renal ATP levels and improved mitochondrial dysfunction. The renal inflammation and fibrosis were ameliorated through inhibiting the MAPKs pathway. In conclusion, fucoidan improved early stage DN targeting the microbiota–mitochondria axis by ameliorating mitochondrial oxidative stress and inhibiting the MAPKs pathway.
Taurine Powder - Pure Bulk Vitamins & Supplements - PureBulk, Inc.
Supplement Facts & Directions Supplement Facts Serving Size: 800 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* Taurine 800 mg † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive. Please call for exact numbers. Other Ingredients: None Contains: Free of: Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives. Directions: As a dietary supplement, take 800 mg (3/16 tsp) up to two times daily, or as directed by a physician. Accurate gram weight scale recommended. Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children. Store in a cool, dark & dry place. Product Details Did You Know? The word taurine comes from the Latin
Unleash the potential of your daily regimen with our pristine BulkSupplements.com Taurine powder. Pure, high-quality, fine powder for seamless mixing, it's the perfect addition to beverages or pre-workout shakes. Fuel your day with a serving of excellence – energizing your ambitions, one serving at a time. Get ready to power through!
! 1 The Dr Ardis Show | Why does Dr Ardis take Taurine?| Episode 04.17.2024
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Investigation of the affinity and interaction of fibrinogen with trehalose as a protein stabilizer - ScienceDirect
Trehalose, a remarkable substance, holds great importance in biomedicine for its anti-inflammatory properties and its capacity to hinder scar formatio…
Sweet regulation – The emerging immunoregulatory roles of hexoses - ScienceDirect
It is widely acknowledged that dietary habits have profound impacts on human health and diseases. As the most important sweeteners and energy sources …
Male Fertility and the Semen Microbiome - David Perlmutter M.D.
It seems as if there is no limit to the various body systems that are now being characterized as having a unique association with bacteria and other resident living organisms. …
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease
Thioredoxin-interacting protein (TXNIP) is an important regulatory protein for thioredoxin (TRX) that elicits the generation of reactive oxygen species (ROS) by inhibiting the redox function of TRX...