These 11 Natural Compounds Help Build New Brain Cells GreenMedInfo
Your brain is capable of making new cells, but this capability declines with age. That is, unless you take action to combat it using lifestyle strategies and neuroprotective compounds found in nature
Myocarditis Once Rare, Now Common GreenMedInfo Blog Entry
The scientific literature indicates that myocarditis is occurring quite frequently in patients harboring the chronic presence of the COVID-related spike protein
1 Know Labs Introduces KnowU, A Portable Medical-Grade Glucose Monitoring Device That Utilizes Bio-RFID Know Labs introduces KnowU, A Portable Glucose Monitoring Device
Know Labs, an emerging leader in non-invasive medical diagnostics, introduced the KnowU™, a new portable medical-grade glucose monitoring device that utilizes Bio-RFID™, Know Labs’ non-invasive diagnostic technology. Related Supersapiens Glucose Display Wearable Is Designed Specifically For Athletes The KnowU is a convenient, non-wearable, on-the-go alternative to fingersticks, which are used to check blood glucose levels, Know Labs introduced KnowU, a new portable medical-grade glucose monitoring device that utilizes Bio-RFID.
The effects of oral trehalose in patients with diabetes a pilot randomized controlled trial
Introduction: Trehalose is a naturally occurring disaccharide of two glucose molecules that has been suggested as a potential therapeutic agent to reduce blood glucose and ameliorate diabetes-related complications in type 2 diabetes (T2D). This study aimed to determine the efficacy of...
Metaformin Users - Consider This - David Perlmutter M.D.
Metformin is one of the most commonly prescribed medications on the planet. It is considered a “first-line” therapy for lowering blood glucose in the treatment of type-2 diabetes and has …
Inhibitory effects of fucoidan from Laminaria japonica against some pathogenic bacteria and SARS-CoV-2 depend on its large molecular weight - ScienceDirect
Fucoidan is a highly sulfated polysaccharide with a wide range of bioactivities, including anti-pathogenic activity. However, the relationship between…
Evidence of the Conspiracy To Commit Mass Murder by the DOD, HHS – Sasha Latypova - LewRockwell
In this presentation, Sasha Latypova covers the pseudo-legal structure, the organizational structure and the money flow of the COVID criminal enterprise. Latypova and I both highly recommend that you subscribe to Katherine Watt’s Bailiwick News Substack. This is the Transcript of Latypova’s conversation with Katherine Watt on November 4, 2022. Here are the DOD contracts for “COVID Countermeasures”. *** NOTES The topic of my presentation today is “Intent to Harm” and I’m going to discuss evidence of conspiracy – which is not a theory – of US Department of Defense, Health and Human Services, other government agencies and other governments all over the world, … Continue reading →
In this minireview, we examine the ability of modified citrus pectin (MCP), a complex water soluble indigestible polysaccharide obtained from the peel and pulp of citrus fruits and modified by means of high pH and temperature treatment, to affect numerous rate-limiting steps in cancer metastasis. Th …
Dr Isaac Eliaz's Modified Citrus Pectin Research to support your understanding of why this ingredient is so effective in supporting healthy cells and body system.
Acute Kidney Injury Induces Remote Cardiac Damage and Dysfunction Through the Galectin-3 Pathway JACC Basic to Translational Science
Highlights • In 2 different mouse models, AKI increased Gal-3 expression and induced cardiac dysfunction, cardiac and systemic inflammation, cardiac macrophage infiltration, and fibrosis. • Cardiac...
Perindopril and a Galectin-3 Inhibitor Improve Ischemic Heart Failure in Rabbits by Reducing Gal-3 Expression and Myocardial Fibrosis - PubMed
Objective: Ventricular remodeling is considered the basis of heart failure and is involved in myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor (modified citrus pectin, MCP) for their effects on ventricular remodeling and myocardial fibrosis in rabbits wit …
Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression - PubMed
Tumor-associated macrophages (TAMs) have been shown to be associated with poor prognosis of cancer and are predominately localized in the hypoxia regions of tumor. We demonstrated in this study that hypoxia increases the synthesis and secretion of galectin-3 by TAMs. The increased expression of gale …
Galectin-3 in septic acute kidney injury a translational study Critical Care Full Text
Background Galectin-3 (Gal-3) is a pleiotropic glycan-binding protein shown to be involved in sepsis and acute kidney injury (AKI). However, its role has never been elucidated in sepsis-associated AKI (S-AKI). We aimed to explore Gal-3’s role and its potential utility as a therapeutic target in S-AKI. Methods In 57 patients admitted to the intensive care unit (ICU) with sepsis, serum Gal-3 was examined as a predictor of ICU mortality and development of AKI. In a rat model of S-AKI induced by cecal ligation and puncture (CLP), 7-day mortality and serum Gal-3, Interleukin-6 (IL-6), and creatinine were examined at 2, 8, and 24 hours (h) post-CLP. Two experimental groups received the Gal-3 inhibitor modified citrus pectin (P-MCP) at 400 mg/kg/day and 1200 mg/kg/day, while the control group received water only (n = 18 in each group). Results Among 57 patients, 27 developed AKI and 8 died in the ICU. Serum Gal-3 was an independent predictor of AKI (OR = 1.2 [95% CI 1.1–1.4], p = 0.01) and ICU mortality (OR = 1.4 [95% CI 1.1–2.2], p = 0.04) before and after controlling for age, AKI, and acute physiology and chronic health evaluation (APACHE II) score. In the CLP rat experiment, serum Gal-3 peaked earlier than IL-6. Serum Gal-3 was significantly lower in both P-MCP groups compared to control at 2 h post-CLP (400 mg: p = 0.003; 1200 mg: p = 0.002), and IL-6 was significantly lower in both P-MCP groups at all time points with a maximum difference at 24 h post-CLP (400 mg: p = 0.015; 1200 mg: p = 0.02). In the Gal-3 inhibitor groups, 7-day mortality was significantly reduced from 61% in the control group to 28% (400 mg P-MCP: p = 0.03) and 22% (1200 mg P-MCP: p = 0.001). Rates of AKI per RIFLE criteria were significantly reduced from 89% in the control group to 44% in both P-MCP groups (400 mg: p = 0.007; 1200 mg: p = 0.007). Conclusions This translational study demonstrates the importance of Gal-3 in the pathogenesis of S-AKI, and its potential utility as a therapeutic target. Graphic abstract
A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury - ScienceDirect
We evaluated Galectin-3 (Gal-3) as a potential early biomarker of acute kidney disease (AKI), and the effect of Gal-3 inhibition by modified citrus pe…
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment - PubMed
Large amounts of tumor-associated macrophages (TAM), which are predominately localized in hypoxia area of the tumor tissue, are associated with the malignant progression of the tumor. In the present study, we investigated the inhibitory effects of modified citrus pectin (MCP), a natural dietary poly …
Modified citrus pectin prevents isoproterenol-induced cardiac hypertrophy associated with p38 signalling and TLR4JAKSTAT3 pathway - PubMed
Modified citrus pectin (MCP) is a specific inhibitor of galectin-3 (Gal-3) that is regarded as a new biomarker of cardiac hypertrophy, but its effect is unclear. The aim of this study is to investigate the role and mechanism of MCP in isoproterenol (ISO)-induced cardiac hypertrophy. Rats were inject …
! 1 The Root Cause of Aging and Chronic Disease - Dr. Isaac Eliaz
Galectin-3 represents one of the fastest-growing fields of medical research, with over 3,000 published studies showing its far-reaching impacts on aging and chronic disease.
