Trehalose-Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis - PubMed
Spinal cord injury (SCI) leads to long-term and permanent motor dysfunctions, and nervous system abnormalities. Injury to the spinal cord triggers a signaling cascade that results in activation of the inflammatory cascade, apoptosis, and Zn(II) ion homeostasis. Trehalose (Tre), a nonreducing disacch …
This Causes Type 2 Diabetes Not Just Glucose or Fats - YouTube
This Causes Type 2 Diabetes Not Just Glucose or Fats
Dr. Barbara E. Corkey was given Banting Award from the American Diabetes Association (ADA) for the groundbreaking work in her 2011 lecture entitled: Hyperinsulinemia: Cause or Consequence. Let's review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Monday, Apr. 14 2023
Frederick Banting - Wikipedia
https://en.wikipedia.org/wiki/Frederick_Banting
Barbara Corkey | Chobanian & Avedisian School of Medicine
https://www.bumc.bu.edu/busm/profile/barbara-corkey/
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Insulin Resistance & Prediabetes - NIDDK
https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Bariatric Surgery for Type 2 Diabetes Reversal: The Risks | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/34/Supplement_2/S361/28238/Bariatric-Surgery-for-Type-2-Diabetes-Reversal-The
Bariatric Surgery to Treat Type 2 Diabetes
https://my.clevelandclinic.org/health/treatments/21153-bariatric-weight-loss-surgery-for-treating-diabetes
Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/42/5/731/40480/Nutrition-Therapy-for-Adults-With-Diabetes-or
International Experts Outline Diabetes Remission Diagnosis Criteria | ADA
https://diabetes.org/newsroom/press-releases/2021/international-experts-outline-diabetes-remission-diagnosis-criteria
Nutritional basis of type 2 diabetes remission | The BMJ
https://www.bmj.com/content/374/bmj.n1449
Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PubMed
https://pubmed.ncbi.nlm.nih.gov/30301822/
Case Report: Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194375/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PubMed
https://pubmed.ncbi.nlm.nih.gov/33521540/
HbA1c Calculator - HbA1c
https://www.hba1cnet.com/hba1c-calculator/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841829/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - PubMed
https://pubmed.ncbi.nlm.nih.gov/29221645/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - CORE Reader
https://core.ac.uk/reader/196576423
(19) Reversing Type 2 Diabetes | Jason Fung - YouTube
https://www.youtube.com/watch?v=6KS7M0s2fJM
NIH study finds heavily processed foods cause overeating and weight gain | National Institutes of Health (NIH)
https://www.nih.gov/news-events/news-releases/nih-study-finds-heavily-processed-foods-cause-overeating-weight-gain
Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine | The American Journal of Clinical Nutrition | Oxford Academic
https://academic.oup.com/ajcn/article/71/6/1511/4729485?login=false
Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism1,2 - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S000291652327495X?via%3Dihub
Trehalose attenuates abdominal aortic aneurysm formation by inducing autophagy in smooth muscle cells
BACKGROUND Trehalose is a naturally occurring disaccharide, which has been identified as an autophagy inducer and exhibits protective effect in cardiovascular diseases such as myocardial infraction and atherosclerosis. However, the functional role of trehalose in abdominal aortic aneurysm (AAA) remains undefined. METHODS To study the effect of trehalose in AAA, trehalose (1 g/kg per day) were given for 14 continuous days in a mouse model of elastase-induced abdominal aortic aneurysm. On day 14, ultrasound was performed to measure aortic diameter before the abdominal aortas were harvested and processed for further analysis. Verhoeff-Van Gieson staining and TUNEL staining were performed on paraffin sections to evaluate vascular histology and apoptosis, immunofluorescence staining and Western-blot were performed to evaluate expression of autophagy markers. RESULTS Echocardiography and in situ pictures demonstrated that trehalose attenuated infrarenal aorta dilation. Verhoeff-Van Gieson staining showed elastin degradation was improved in trehalose-treated group. Compared with vehicle-treated mice, trehalose treatment restored smooth muscle cell contractile phenotype with increased α-SMA, Calponin and Myh11 expression. Furthermore, trehalose also attenuated cell apoptosis and leukocytes infiltration. Importantly, trehalose induced autophagy with decrease SQSTM1/p62 accumulation, increased lamp2 expression and LC3B conversion. CONCLUSION Trehalose attenuated AAA progression with decreased inflammation and restored SMC contractile phenotype by inducing autophagy. These results demonstrated the therapeutic potential of trehalose in AAA.
Unraveling Complex Chronic Illness Restoring Vitality We are internationally recognized thought leaders and practitioners specializing in difficult to diagnose illnesses. Our approach includes functional medicine as the foundation, combined with a constant exploration of new and often rediscovered treatments. This gives us the tools to help people wrestling with the unique characteristics of their illness. […]
Discussing Long COVID with Dr. J.P. Saleeby - YouTube
In March Dr. Saleeby invited me for a talk for his 6th annual functional medicine symposium. We discussed a number of topics including long COVID, intermitte...
Discussing Long COVID with Dr. J.P. Saleeby - YouTube
In March Dr. Saleeby invited me for a talk for his 6th annual functional medicine symposium. We discussed a number of topics including long COVID, intermittent fasting, monocyte holding on to the S1 component of the spike protein, methylene blue, near infrared light, Neil Jenkin's theory for anti-ACE2 antibodies, low dose naltrexone (LDN), and autophagy.
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#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
00:00 Introduction
01:24 FLCCC Protocol Review
05:45 Intermittent fasting
15:27 Macro-autophagy
22:10 Mitochondrial dysfunction
25:40 Infrared and red light
33:15 Auto-antibodies
The Big Fat Surprise - Why Dietary Guidelines are Making us Fat - David Perlmutter M.D.
What underlies the war on fat? It’s big business, wanting us all to eat more refined carbs and sugar to replace the fat calories that we’ve been instructed to reduce. …
250+ Examples of Natural Remedies Beating Pharmaceuticals
You hear a lot about 'natural healing' these days, but did you know that a sizable body of scientific literature actually supports the idea that natural medicine is safer and more effective than conventional, drug-based medicine?
Dr. Keith Berkowitz Discusses Long COVID Management (April 11th, 2023) - YouTube
Dr. Keith Berkowitz Discusses Long COVID Management (April 11th, 2023)
Keith Wayne Berkowitz, M.D., is the Founder and Medical Director of the Center for Balanced Health. He combines expertise in both traditional and complementary medicine. Prior to starting the Center for Balanced Health, he was the Medical Director and Business Director of The Atkins Center for Complementary Medicine. He was an associate of Dr. Robert C. Atkins since 1999.
If you like this content and want more, I am doing a special one-time membership offer. Click here: https://www.drbeen.com/yt-special/
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Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Is Type 2 Diabetes Reversible?
In this informative video, Dr. Mobeen Syed sheds light on the root causes of this widespread health issue and how to reverse it by lifestyle changes. By understanding the underlying factors behind type 2 diabetes, you can learn how to effectively combat it with dietary methods. Let's learn because your health matters.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special-p/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Monday, Apr. 10 2023
Frederick Banting - Wikipedia
https://en.wikipedia.org/wiki/Frederick_Banting
Barbara Corkey | Chobanian & Avedisian School of Medicine
https://www.bumc.bu.edu/busm/profile/barbara-corkey/
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Insulin Resistance & Prediabetes - NIDDK
https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Bariatric Surgery for Type 2 Diabetes Reversal: The Risks | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/34/Supplement_2/S361/28238/Bariatric-Surgery-for-Type-2-Diabetes-Reversal-The
Bariatric Surgery to Treat Type 2 Diabetes
https://my.clevelandclinic.org/health/treatments/21153-bariatric-weight-loss-surgery-for-treating-diabetes
Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/42/5/731/40480/Nutrition-Therapy-for-Adults-With-Diabetes-or
International Experts Outline Diabetes Remission Diagnosis Criteria | ADA
https://diabetes.org/newsroom/press-releases/2021/international-experts-outline-diabetes-remission-diagnosis-criteria
Nutritional basis of type 2 diabetes remission | The BMJ
https://www.bmj.com/content/374/bmj.n1449
Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PubMed
https://pubmed.ncbi.nlm.nih.gov/30301822/
Case Report: Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194375/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PubMed
https://pubmed.ncbi.nlm.nih.gov/33521540/
HbA1c Calculator - HbA1c
https://www.hba1cnet.com/hba1c-calculator/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841829/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - PubMed
https://pubmed.ncbi.nlm.nih.gov/29221645/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - CORE Reader
https://core.ac.uk/reader/196576423
NIH study finds heavily processed foods cause overeating and weight gain | National Institutes of Health (NIH)
https://www.nih.gov/news-events/news-releases/nih-study-finds-heavily-processed-foods-cause-overeating-weight-gain
Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine | The American Journal of Clinical Nutrition | Oxford Academic
https://academic.oup.com/ajcn/article/71/6/1511/4729485?login=false
Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism1,2 - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S000291652327495X?via%3Dihub
Gum Acacia attenuates cisplatin toxic effect spermatogenesis dysfunction and infertility in rats - ScienceDirect
This study aimed to investigate the potential benefits Gum Arabic/Acacia Senegal (GA) in mitigating the harmful effects of cisplatin (CP) on spermatog…
Radishes Are Surprisingly Good for You | GreenMedInfo | Blog Entry
Radishes are root vegetables that not only add a welcome crunch to your salads and a tangy pickled taste to your meals, but also provide beneficial effects for your heart, urinary tract and more
Combined treatment with glucosamine and chondroitin sulfate improves rheumatoid arthritis in rats by regulating the gut microbiota | Nutrition & Metabolism | Full Text
Background To investigate the ameliorative effects of glucosamine (GS), chondroitin sulphate (CS) and glucosamine plus chondroitin sulphate (GC) on rheumatoid arthritis (RA) in rats, and to explore the mechanism of GS, CS and GC in improving RA based on the gut microbiota. Methods RA rat models were effectively developed 14 days after CFA injection, and then garaged with GS, CS and GC. Body weight and paw volume of rats were monitored at multiple time points at the beginning of CFA injection. Until D36, serum and ankle tissue specimens were used to measure levels of circulating inflammatory factors (TNF-α, IL-1β, MMP-3, NO and PGE2) and local inflammatory indicators (TLR-4 and NF-κB). On D18, D25, and D36, intergroup gut microbiota was compared using 16S rRNA gene sequencing and bioinformatics analysis. We also performed the correlation analysis of gut bacteria, joint swelling and inflammatory indicators. Results GC, rather than GS and CS, could reduce right paw volumes, levels of TLR-4 and NF-κB in synovial tissues. In addition, enriched genera in RA model rats screened out by LEfSe analysis could be inhibited by GC intervention, including potential LPS-producing bacteria (Enterobacter, Bacteroides, Erysipelotrichaceae_unclassified and Erysipelotrichaceae_uncultured) and some other opportunistic pathogens (Esherichia_Shigella, Nosocomiicoccus, NK4A214_group, Odoribacter, Corynebacterium and Candidatus_Saccharimonas.etc.) that positively correlated with pro-inflammatory cytokines, right paw volume, and pathology scores. Furthermore, the gut microbiota dysbiosis was observed to recover before alleviating joint swelling after interventions. Conclusions GC could inhibit potential LPS-producing bacteria and the activation of TLR-4/NF-κB pathway in RA rats, thus alleviating RA-induced joint injury.