Parkinsons

Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves led to the hypothesis that the intestine might be an early site of PD disease in response to an environmental toxin or pathogen. One potential mechanism for environmental toxin(s) and proinflammatory luminal products to gain access to mucosal neuronal tissue and promote oxidative stress is compromised intestinal barrier integrity. However, the role of intestinal permeability in PD has never been tested. We hypothesized that PD subjects might exhibit increased intestinal permeability to proinflammatory bacterial products in the intestine. To test our hypothesis we evaluated intestinal permeability in subjects newly diagnosed with PD and compared their values to healthy subjects. In addition, we obtained intestinal biopsies from both groups and used immunohistochemistry to assess bacterial translocation, nitrotyrosine (oxidative stress), and alpha-synuclein. We also evaluated serum markers of endotoxin exposure including LPS binding protein (LBP). Our data show that our PD subjects exhibit significantly greater intestinal permeability (gut leakiness) than controls. In addition, this intestinal hyperpermeability significantly correlated with increased intestinal mucosa staining for E. coli bacteria, nitrotyrosine, and alpha-synuclein as well as serum LBP levels in PD subjects. These data represent not only the first demonstration of abnormal intestinal permeability in PD subjects but also the first correlation of increased intestinal permeability in PD with intestinal alpha–synuclein (the hallmark of PD), as well as staining for gram negative bacteria and tissue oxidative stress. Our study may thus shed new light on PD pathogenesis as well as provide a new method for earlier diagnosis of PD and suggests potential therapeutic targets in PD subjects. Trial Registration Clinicaltrials.gov NCT01155492

Sarah King, PT, DPT shows people diagnosed with Parkinson's Disease how to create a personalized Parkinson’s action plan that improves their symptoms, so they can spend less time worrying and more time doing the things they love, with the people they love, for as long as possible.

Science says eating just one meal per day can improve your health. Learn more at https://highintensityhealth.com/OMAD ----- Connect with Bill Curtis: https://www.thefourthfoodgroup.com/ Related Video testing the KetoAid Ketone Ester: https://youtu.be/V-ILObXYsaQ This episode is brought to you by: ➢ Health IQ, an insurance company that helps health conscious people like weightlifters, cyclist, keto dieters and vegetarians get lower rates on their life insurance. ➢ Get a Free Quote: http://healthiq.com/HIH Somnifix.com, the world’s only hypoallergenic mouth tape, developed by Harvard Scientists. https://www.somnifix.com Key Timestamps: 01:55 Journalist Bill Curtis has had Parkinson's since 2000. As predicted, he was dramatically affected 10 years later with advanced Parkinson's. Now the only symptom he has is a slight tremor. 04:48 Within about 2 hours of eating carbs, Bill will begin to shake and feel rigid. He doesn't get the full on symptoms he had before. 07:38 Bill was in an exercise program. In an attempt to enhance the effects of the program, he fasted overnight and had nothing for breakfast before the workout. He found it alleviated his profound fatigue. 11:27 Fasting helped with the fatigue, but there were many more symptoms that were not reversed. Bill continued researching. 13:02 Bill exercised fasted every day for a year. He lost weight, but eventually, it stopped working. As you become fit, you make fewer ketones. 15:04 Dr. Veech suggested that Bill try Bulletproof Coffee after the night fast. Nearly all of his symptoms abated at the end of the first hour. 19:36 The military has been experimenting with Dr. Veech's ketone ester for radiation exposure. 22:26 A therapeutic ketogenic diet is one with 80 to 90% of your food as fat. Bill has devised 4 levels of ketosis. 30:33 Within the first 10 days of taking ketone ester, Bill no longer had urinary incontinence. 32:07 There is data that an elevation of uric acid it will delay the onset of Parkinson's. If you have Parkinson's, and your uric acid levels are higher, you decline more slowly. 36:14 BHB allows you to make more dopamine, serotonin, adrenaline, noradrenaline and nitric oxide. 38:00 In advanced Parkinson's neurotransmitters are negatively impacted. With ketosis, you are making serotonin, noradrenaline, adrenaline, dopamine and nitric oxide synthase. 38:52 Every antioxidant has to be recharged with an electron from NADPH, directly or indirectly. 39:50 Beta hydroxybutyrate raises NADPH levels using isocitrate dehydrogenase in the cytoplasm, outside of the mitochondria. 42:24 NADPH levels in the mitochondria does not correlate with NADPH levels in the cytosol. We should measure the cytosolic NADPH. 44:09 NADPH voltage is dependent upon the relative concentrations. More equals more resilience. 48:52 Dismutase does not get its electrons from the battery. It does this by taking 2 molecules of superoxide, oxidizing one and reducing the other. 52:59 You have the ability to use ketones to restore ischemia-reperfusion and turn off inflammation. 54:08 NADPH controls inflammation. 55:04 Dr. Veech found that treating Alzheimer's mouse models with beta hydroxybutyrate kept them from accumulating beta amyloid deposits. 58:03 Bill believes that TBI will respond very well to BHB, as evidenced by people close to him with head injuries. 01:02:41 Bill has created an online course to help people help each other. You need a cook, a coach, a nutritionist and a doctor. 01:04:36 Bill must still take his Parkinson's medications.

The low-carb keto diet gets debunked once and for all! For more information head over to masteringdiabetes.org WIN THE OPPORTUNITY TO STUDY PLANT BASED NUTRITION COURSE WITH ECORNELL - www.plantbasednews.org/competitions/win-with-pbn --- ★ SUPPORT OUR WORK BY MAKING A CONTRIBUTION: https://www.plantbasednews.org/support ★ GET OUR FREE MEAL INSPIRATION GUIDE: http://bit.ly/pbnmealguide ★ HELP TRANSLATE OUR VIDEOS: http://bit.ly/translatePBN ★ SIGN UP TO RECEIVE OUR WEEKLY HEADLINES IN YOUR INBOX: http://www.plantbasednews.org/signup ★ GOT A NEWS STORY WE SHOULD KNOW ABOUT? Please email press@plantbasednews.org or leave a message on our hotline UK landline: +44 207 0960 175, US landline: +1 818 963 5411 ★ CHECK OUT OUR WEBSITE: http://www.plantbasednews.org/ SOCIAL MEDIA ★ TWITTER: https://www.twitter.com/plantbasednews ★ FACEBOOK: https://www.facebook.com/plantbasednews ★ YOUTUBE: https://www.youtube.com/plantbasednews ★ INSTAGRAM: https://www.instagram.com/plantbasednews LEARN ABOUT VEGANISM ★ Cowspiracy ➞ https://youtu.be/nV04zyfLyN4 ★ NutritionFacts.Org ➞ https://goo.gl/BdNbiU ★ Veganuary ➞ http://www.veganuary.com/

This article originally appeared in the Fall 2016 issue of Health Science magazine, the member magazine of the National Health Association. Csilla Veress, N.D., L.Ac is a Naturopathic doctor and Licensed Acupuncturist at TrueNorth Health Center in Santa Rosa, California. She received her Master’s in Acupuncture and Oriental Medicine, and her Doctorate in aturopathic medicine from Bastyr University. While in medical school, Dr. Veress completed a two-year internship in cancer research at Bastyr Integrative Oncology Research Center. She has completed additional training in Classical Homeopathy at the New England School of Homeopathy and advanced comprehensive neurotransmitter training at/from Institute of Neurotransmitter Science. Dr. Veress is passionate about preventative care, and emphasizes nutrition-based medicine. She implements natural hygiene and a Naturopathic medical approach, supporting patients to heal their bodies through lifestyle, food, and water fasting. Parkinson’s disease is a progressive and debilitating neurological disorder that affects one million Americans and more than four million people worldwide. It is not known exactly what causes Parkinson’s disease (PD) and it is without a cure.  According to the National Institute of Neurological Disorders and Stroke, PD affects more men than women (by 50%), and is found more often in older people (60 years old on average, although “early onset” can occur before age 50). Total risk is 2 to 5% unless a family member has a known gene for the disease. Knowing exactly how many cases of PD exist is difficult (the estimate is about 50,000 a year in the U.S.) since in the early stages many people think that their symptoms reflect normal aging, so they don’t consult their doctors. Other health conditions may also present symptoms similar to PD (there is no definitive test to find out if someone has the disease). Tremors in the arms or legs are considered the hallmark of Parkinson’s, though the disease inevitably progresses. As motor control diminishes, simple tasks like writing and walking are typically the first to go. Patients eventually become wheelchair-bound and suffer from dementia. But perhaps most disturbing is that Parkinson’s disease responds poorly to conventional therapy. Click here to read the entire article as a PDF.

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Parkinson's disease (PD) is a progressive neurodegenerative disease for which stem cell research has created hope in the last few years. Seven PD pati…

The following Parkinsons Disease Health plan is designed to provide relief. With a naturally healthy lifestyle, it’s possible to improve Parkinson's Disease

“When I first contacted Dr. Sircus to consult with him, I was in desperate need of help. My elderly husband, diagnosed with Parkinson’s, suddenly began to decline rapidly over five months. He had no appetite, lost weight, and gradually lost the ability to walk, even with a walker. His legs were swollen from the ankles... View Article

The main serrapeptase benefits is the anti-inflammatory property without the side effect. This supplement may prevent pain, similar to ibuprofen and aspirin; without thinning the blood. Additionally, it has been shown to help prevent plaque buildup in the heart arteries

[Facebook LIVE Replay] Are you interested in combating PD symptoms without simply taking more medication? Dr. Sarah King, PT, DPT chats with Colin Potter, founder of Fight Parkinsons, about his holistic approach to PD. www.InvigoratePT.com Here's a breakdown of the conversation: 3:00 - Quick Disclaimer 7:30 - Colin’s Background - self-employed problem-solver 10:00 - Colin’s initial symptoms (3 years before official diagnosis) 12:55 - When Colin started taking medication 14:14 - The gift Colin received that changed everything 15:50 - The #1 thing Colin learned initially that launched his journey (hint: it’s at the heart of most chronic diseases) 19:04 - Peek into Colin’s diet 21:30 - How long it took for him to start seeing results (and his transition off medication) 24:00 - Colin’s advice on where to start with nutrition, exercise, supplementation, and toxin elimination upgrades 25:55 - How Colin developed an optimistic mindset and how he stays motivated to keep fighting 28:00 - What Colin’s able to do now physically that he couldn’t do 4 years ago 29:27 - The role of exercise in Colin’s recovery plan 31:49 - Colin’s #1 Reading recommendation 34:53 - Colin’s supplementation program - then and now 38: 55 - The physician who Colin sees primarily to help him guide his natural treatment program (and their plan of attack) 45:20 - A recent victory that Colin got wildly excited about! 47:30 - Steps that Colin recommends when just starting out on your journey 53:45 - The role of toxins in brain health and where they show up in our daily life 55:55 - Answer to the question "Do I have to go 100% for these efforts to be worth it?" 1:00:10 - Constipation, Urinary Frequency, and Colon Hydrotherapy… oh my! 1:04:00 - Colin’s take on dairy in his diet 1:09:50 - The role of medication in a thriving Parkinson's recovery program

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Researchers are just now starting to link inflammation in your gut with some of the most deadly and debilitating diseases we have.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today.

Magnesium oil, cannabis and Iodine are natural medicinals that have been found to be a remarkable help in decreasing the pain and spasms and increasing functioning, language, and better attention in Parkinson's disease.

Parkinson's disease (PD) is a progressive movement disorder resulting primarily from loss of nigrostriatal dopaminergic neurons. PD is characterized by the accumulation of protein aggregates, and evidence suggests that aberrant protein deposition in dopaminergic neurons could be related to the dysre …