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Trehalose is a disaccharide and fasting-mimetic that has been both canonized and vilified for its putative cardiometabolic and microbial effects. Trehalose analogues are currently under development to extend the key metabolic therapeutic actions of trehalose ...

In our ever-increasingly polarized world, there’s one topic of interest in health and wellness that really seems to call out clear differences in opinion. Glyphosate, the herbicide and active ingredient in products like Roundup, has been touted by some as being a wonderful and safe way to rid crops and even homes of pesky weeds. And clearly, those who feel positively about this chemical are being heard as nearly 150,000 tons of glyphosate are sprayed onto American crops every year. That translates to about one pound of glyphosate for every person in our country. And this chemical makes its way into the water we drink, the agricultural products we consume, and even the air we breathe. On the other side of this debate are those who feel that glyphosate represents a significant threat to our health. Researchers, like our guest today, look at the available science and have concluded that, by a multitude of mechanisms, glyphosate may well be responsible or at least contributory for a vast array of human ailments, from autism to dementia to autoimmune disease, and so many more. This debate extends to the confusion surrounding the safety of GMO food. For the most part, the genetic modification of plant seeds is undertaken so that the newly developed plant is not damaged by the weed targeting action of glyphosate. This allows farmers to spray GMO crops with glyphosate, kill the weeds, and still harvest the undamaged plant. But while there may or may not be concern about the specific genetic modification of the plant, this whole scenario sets the stage for glyphosate to appear in our foods and throughout our environment. That said, this is a fundamental nuance to the GMO debate that absolutely must enter the discussion. ==== Stephanie Seneff, PhD is a senior research scientist at MIT’s Computer Science and Artificial Intelligence Laboratory. She has a bachelor’s degree in biology with a minor in food and nutrition, and a master’s degree, an engineer’s degree, and a PhD in electrical engineering and computer science, all from MIT. She has authored over three dozen peer-reviewed journal papers on topics relating human disease to nutritional deficiencies and toxic exposures. She has focused specifically on the herbicide glyphosate and the mineral sulfur. Dr. Seneff splits her time equally between two homes in Hawaii and Massachusetts. She is the author of Toxic Legacy: How the Weedkiller Glyphosate is Destroying Our Health and the Environment (Chelsea Green Publishing, June 2021). Author Website: https://stephanieseneff.net/ Twitter: @stephanieseneff Facebook: https://www.facebook.com/stephanie.seneff.5 LinkedIn: https://www.linkedin.com/in/stephanie-seneff-9a04958/ ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

Wheat consumption has been linked to psychiatric conditions like schizophrenia for over 60 years, but recent research indicates the mind-altering properties of this popular food are, in part, caused by it cutting off blood flow to the frontal cortex of the brain.

Could long sought-after support for type 1 diabetes be as close as your kitchen cupboard? An accumulating body of scientific research appears to point in exactly that direction

With over 20,000 consultations, Dr Ben Marble and his network of doctors have been leading the way with their free telemedicine service for the early treatment of COVID-19 in the USA. Learn about how this initiative came to birth, how it evolved, and what's in store for further expanding the initiative, both nationally and internationally. Find the audio podcast version at: https://covexit.com/interview-of-dr-ben-marble-founder-president-of-myfreedoctor-com/

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In an email obtained by ICAN, through a FOIA requested submitted by its attorneys, a CDC Senior Scientist in the CDC’s Immunization Safety Office (ISO) calls the Director of that […]

Commentary “The high-profile scientist who was fired from Canada’s top infectious disease lab collaborated with Chinese government scientists ...

I started writing Hydrogen Medicine over three years ago, and it certainly has been a work of love and science. It is now available in its latest edition in soft and hardcover. It is one of the only two books on hydrogen in the world; and how it can be used in medicine and as... View Article

Traumatic brain injury (TBI) in its various forms has emerged as a major problem for modern society. Acute TBI can transform into a chronic condition and be a risk factor for neurodegenerative diseases such as Alzheimer’s and Parkinson’s ...

Biomedical properties of hydrogen water have been extensively investigated, but the effect of hydrogen on good healthy subjects remains unclear. This study was designed to explore the hygiene improvement by electrolytically generated hydrogen warm water ...

Chronic obstructive pulmonary disease (COPD) is a progressive pulmonary disease caused by harmful gases or particles. Recent studies have shown that 2% hydrogen or hydrogen water is effective in the treatment and prevention of a variety of diseases. This ...

Therapeutic effects of molecular hydrogen for a wide range of disease models and human diseases have been investigated since 2007. A total of 321 original articles have been published from 2007 to June 2015. Most studies have been conducted in Japan, ...

Hydrogen-rich water is conventionally prepared by direct current-electrolysis, but has been not or scarcely prepared by alternating current (AC)-electrolysis. The AC preparations from tap water for 20–30 minutes exhibit a dissolved hydrogen concentration ...

Dr. Lisa Willis, Assistant Professor at the University of Alberta, is introduced by Dr. Lara Mahal (University of Alberta) in this episode of Joint Webinar Series to speak about glycoengineering sialic acid and insights into sex differences in human sialic acid. The Joint Webinar Series is a collaborative effort by GlycoNet and American Chemical Society's Carbohydrate Chemistry Division. The series is sponsored by New England Biolabs. To learn more, visit http://bit.ly/glycowebinar

Gestational diabetes mellitus (GDM) is a pregnancy complication first detected in the second or third trimester in women that did not show evident glucose intolerance or diabetes before gestation. In 2019, the International Diabetes Federation reported that 15.8% of live births were affected by hyperglycemia during pregnancy, of which 83.6% were due to gestational diabetes mellitus, 8.5% were due to diabetes first detected in pregnancy, and 7.9% were due to diabetes detected before pregnancy. GDM increases the susceptibility to developing chronic diseases for both the mother and the baby later in life. Under GDM conditions, the intrauterine environment becomes hyperglycemic, while also showing high concentrations of fatty acids and proinflammatory cytokines, producing morphological, structural, and molecular modifications in the placenta, affecting its function; these alterations may predispose the baby to disease in adult life. Molecular alterations include epigenetic mechanisms such as DNA and RNA methylation, chromatin remodeling, histone modifications, and expression of noncoding RNAs (ncRNAs). The placenta is a unique organ that originates only in pregnancy, and its main function is communication between the mother and the fetus, ensuring healthy development. Thus, this review provides up-to-date information regarding two of the best-documented (epigenetic) mechanisms (DNA methylation and miRNA expression) altered in the human placenta under GDM conditions, as well as potential implications for the offspring.

During the last years, epigenetic processes have emerged as important factors for many neurodegenerative diseases, such as Alzheimer’s disease (AD). These complex diseases seem to have a heritable component; however, genome-wide association studies failed to identify the genetic loci involved in the etiology. So, how can these changes be transmitted from one generation to the next? Answering this question would allow us to understand how the environment can affect human populations for multiple generations and explain the high prevalence of neurodegenerative diseases, such as AD. This review pays particular attention to the relationship among epigenetics, cognition, and neurodegeneration across generations, deepening the understanding of the relevance of heritability in neurodegenerative diseases. We highlight some recent examples of EI induced by experiences, focusing on their contribution of processes in learning and memory to point out new targets for therapeutic interventions. Here, we first describe the prominent role of epigenetic factors in memory processing. Then, we briefly discuss aspects of EI. Additionally, we summarize evidence of how epigenetic marks inherited by experience and/or environmental stimuli contribute to cognitive status offspring since better knowledge of EI can provide clues in the appearance and development of age-related cognitive decline and AD.

The Food and Drug Administration (FDA) said on Wednesday that it will add a warning of heart inflammation ...

Official Chinese state-approved footage from four years ago showing bats being kept at the Wuhan Institute of Virology ...

Trehalose is a naturally occurring disaccharide known to remarkably stabilize biomacromolecules in the biologically active state. The stabilizing effect is typically observed over a large concentration range and affects many macromolecules including proteins, ...

A group of concerned parents had children's face masks independently tested after they'd been worn for a typical school day. The startling results reveal a range of bacteria associated with pathogenicity, including 11 strains scientists described as "quite dangerous"

Gastroesophageal reflux disease (), a clinical condition characterized by reflux of gastroduodenal contents in the oesophagus, has proved to demonstrate a strong link between oxidative stress and the development of . Proton pump inhibitors (s) have been ...

In Japan, alkaline electrolyzed water (AEW) apparatus have been approved as a medical device. And for the patients with gastrointestinal symptoms, drinking AEW has been found to be effective in relieving gastrointestinal symptoms. But some users of AEW ...