Aloe Vera Extract For Stomach Acid Use Safe And Effective Treatment International Journal Papier Advance and Scientific Review
The purpose of this study was to determine the effectiveness of aloe vera juice against stomach acid. Aloe vera also contains key elements such as resin, aloin, tannins, aloin-emodin, polysaccharides, 19 amino acids, 12 vitamins and 20 minerals that are important for health. Aloe vera is a natural ingredient that is good for detoxifying heavy metals in the body, and is able to maximize the performance of the digestive system. consuming aloe vera juice in a certain dose, is very effective for healing wounds in the stomach, as well as being a natural remedy for stomach ulcers which is quite effective. Aloe vera has the ability to stimulate the release of pepsin, which is an enzyme in the stomach that works to support the digestive system
Trehalose Ameliorates Diabetic Cardiomyopathy Role of the PK2PKR Pathway
Ample clinical case reports suggest a high incidence of cardiomyopathy in diabetes mellitus (DM). Recent evidence supports an essential role of trehalose (TLS) in cardiomyocyte survival signaling. Our previous study found that prokineticin2 (PK2) was involved in the process of diabetic cardiomyopathy (DCM). The present study examined the protective effects and mechanisms of TLS on DM-induced cardiomyocyte injury in mice and H9c2 cardiomyocytes. C57BL/6J mice were intraperitoneally injected with 50 mg·kg-1·d-1 streptozotocin for five consecutive days to establish an experimental diabetic model and then administered TLS (1 mg·g-1·d-1, i.p.) for two days every 4 weeks and given 2% TLS in drinking water for 24 weeks. Echocardiography, myocardial structure, apoptosis, pyroptosis, autophagy, and the PK2/PKR pathway were assessed. Cardiomyocytes exposed to high glucose (HG) were treated with TLS in the absence or presence of the PK2 antagonist PKRA7, and proteins involved in apoptosis, autophagy, and pyroptosis and the PK2/PKR pathways were evaluated using Western blot analysis. Diabetic mice demonstrated metabolic disorder, abnormal myocardial zymograms, and aberrant myocardial systolic and diastolic function, which were accompanied by pronounced apoptosis, pyroptosis, and dampened autophagy. TLS treatment relieved these effects. PK2 and receptor expressions were downregulated in diabetic mice, and TLS nullified this effect. PKRA7 eliminated the impact of TLS on cardiomyocytes. This evidence suggests that TLS rescues DM-induced myocardial function, pyroptosis, and apoptosis, likely via the PK2/PKR pathway.
Facebook Admits Its Fact Checks Are Just Opinions GreenMedInfo
In a court filing, attorneys for Meta, formerly Facebook, admit that their fact check labels aren't based on facts at all -- they're actually just opinions
Good news Mild COVID-19 induces lasting antibody protection
People who have had a mild case of COVID-19 are left with long-term antibody protection against future disease, according to a study from researchers at Washing
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans Nature
Nature - SARS-CoV-2 infection induces long-lived bone marrow plasma cells that correlate with anti-SARS-CoV-2 spike protein antibody titres in individuals who have recovered from COVID-19.
Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2 - PubMed
The ivermectin docking we identified may interfere with the attachment of the spike to the human cell membrane. Clinical trials now underway should determine whether ivermectin is an effective treatment for SARS-Cov2 infection.
Antioxidants Free Full-Text Antioxidants into Nopal (Opuntia ficus-indica), Important Inhibitors of Free Radicals’ Formation HTML
Nopal (Opuntia ficus indica) belonging to the Cactacea family has many nutritional benefits attributed to a wide variety of phenolic and flavonoid compounds. Coumaric acid (COA), ferulic acid (FLA), protocatechuic acid (PRA), and gallic acid (GAA) are the phenolic acids (PhAs) present in nopal. In this study, the role of these PhAs in copper-induced oxidative stress was investigated using the density functional theory (DFT). The PhAs form 5 thermodynamically favorable complexes with Cu(II), their conditional Gibbs free energies of reaction (ΔG’, at pH = 7.4, in kcal/mol) are from −23 kcal/mol to −18 kcal/mol. All of them are bi-dentate complexes. The complexes of PRA and GAA are capable of inhibiting the Cu(II) reduction by both O2•− and Asc−, their reactions with the chelated metal are endergonic having rate constants about ~10−5–102 M−1 s−1, PhAs can prevent the formation of hydroxyl free radicals by chelating the copper ions. Once the hydroxyl radicals are formed by Fenton reactions, the complexes of PhAs with Cu(II) can immediately react with them, thus inhibiting the damage that they can cause to molecules of biological interest. The reactions between PhAs-Cu(II) complexes and hydroxyl free radical were estimated to be diffusion-limited (~108 M−1s−1). Thus, these chelates can reduce the harmful effects caused by the most reactive free radical existent immediately after it is formed by Fenton reactions.
In this interview with internationally renowned Dr. Shankara Chetty from South Africa, we discuss the Omicron variant, which is taking the world as a storm. Is this variant to be feared, or could it actually be a positive development in this pandemic, as mostly inducing mild disease, yet conferring post-covid natural immunity. These are among the timely and critically important aspects we discuss.
Dr. Chetty is a Family General Medical Practitioner in South-Africa, with considerable experience with the outpatient treatment of COVID-19, having treated so far nearly 8,000 patients, in his outpatient practice, without any of them requiring hospitalization or even oxygen.
Dr. Chetty holds a degree in medicine and surgery and also has advanced education in genetics, advanced biology, biochemistry and microbiology.
More interviews:
https://covexit.com/category/videos/
Scientists identify gut-derived metabolites that play a role in neurodegeneration -- ScienceDaily
A New York-based, multi-institutional research team has found high levels of three toxic metabolites produced by gut bacteria in the cerebrospinal fluid and plasma samples of multiple sclerosis (MS) patients. The important findings further scientists' understanding of how gut bacteria can impact the course of neurological diseases by producing compounds that are toxic to nerve cells.
An Integrated Plan for Lowering Uric Acid - Dr. David Perlmutter MD
Let’s unpack a unique compilation of supplements and explore not just the value of each component and how they work synergistically to lower uric acid.
Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection bioRxiv
The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected individuals. The underlying mechanism and source of this distinct immunologic condition three months or more after initial infection remains elusive. Here, we investigated the presence of SARS-CoV-2 S1 protein in 46 individuals. We analyzed T-cell, B-cell, and monocytic subsets in both severe COVID-19 patients and in patients with post-acute sequelae of COVID-19 (PASC). The levels of both intermediate (CD14+, CD16+) and non-classical monocyte (CD14Lo, CD16+) were significantly elevated in PASC patients up to 15 months post-acute infection compared to healthy controls (P=0.002 and P=0.01, respectively). A statistically significant number of non-classical monocytes contained SARS-CoV-2 S1 protein in both severe (P=0.004) and PASC patients (P=0.02) out to 15 months post-infection. Non-classical monocytes were sorted from PASC patients using flow cytometric sorting and the SARS-CoV-2 S1 protein was confirmed by mass spectrometry. Cells from 4 out of 11 severe COVID-19 patients and 1 out of 26 also contained SARS-CoV-2 RNA. Non-classical monocytes are capable of causing inflammation throughout the body in response to fractalkine/CX3CL1 and RANTES/CCR5. Summary SARS CoV-2 S1 Protein in CD16+ Monocytes In PASC ### Competing Interest Statement B.K.P, A.P., H.R., E.L, and EBF. are employees of IncellDx
Had COVID You’ll probably make antibodies for a lifetime
Nature - People who recover from mild COVID-19 have bone-marrow cells that can churn out antibodies for decades, although viral variants could dampen some of the protection they offer.
1 Investigation and Prosecution of Those Individuals Responsible for Crimes Against Humanity
Investigation and Prosecution of Those Individuals Responsible for Crimes Against Humanity 29 September 2021 The International Criminal Court Office of the Prosecutor Post Office Box 19519 2500 CM The Hague The Netherlands And Ms. Karen Mosoti, or official replacement for the office of Liaison Office of the International Criminal Court to the United Nations 866 United Nations Plaza Suite 476 New York, NY, 10017 USA 212-486-1346/47/62 Email: otp.informationdesk@icc-cpi.int Dear
Revealed Vaccine Induced Cellular Aging - The HighWire
By Dr. Mike Williams21stcenturywire.com In prior articles we discussed the increased risk of SARS-COV-2 infection after Covid vaccination and introduced concepts of immune tolerance and immune training. In this article I want to introduce the topic of cellular senescence, specifically as it relates to Covid vaccination. From Cellular Senescence: What, Why, and How we learn: Cellular senescence is a process […]