2016

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In Vitro Wound-Healing Potential of Phenolic and Polysaccharide Extracts of Aloe vera Gel
In Vitro Wound-Healing Potential of Phenolic and Polysaccharide Extracts of Aloe vera Gel
The present study aimed to conduct a comparative investigation of the biological properties of phenolic and polysaccharide extracts obtained using an ultrasound-assisted technique from Aloe vera gel and their effects on each stage of the wound healing process in in vitro experimental models. HPLC analysis showed that the phenolic extract contained aloin, ferulic, and caffeic acid, as well as quercetin dihydrate, as major compounds. Capillary zone electrophoresis indicated the prevalence of mannose and glucose in the polysaccharide extract. Cell culture testing revealed the anti-inflammatory properties of the phenolic extract at a concentration of 0.25 mg/mL through significant inhibition of pro-inflammatory cytokines—up to 28% TNF-α and 11% IL-8 secretion—in inflamed THP-1-derived macrophages, while a pro-inflammatory effect was observed at 0.5 mg/mL. The phenolic extract induced 18% stimulation of L929 fibroblast proliferation at a concentration of 0.5 mg/mL, enhanced the cell migration rate by 20%, and increased collagen type I synthesis by 18%. Moreover, the phenolic extract exhibited superior antioxidant properties by scavenging free DPPH (IC50 of 2.50 mg/mL) and ABTS (16.47 mM TE/g) radicals, and 46% inhibition of intracellular reactive oxygen species (ROS) production was achieved. The polysaccharide extract demonstrated a greater increase in collagen synthesis up to 25%, as well as antibacterial activity against Staphylococcus aureus with a bacteriostatic effect at 25 mg/mL and a bactericidal one at 50 mg/mL. All these findings indicate that the phenolic extract might be more beneficial in formulations intended for the initial phases of wound healing, such as inflammation and proliferation, while the polysaccharide extract could be more suitable for use during the remodeling stage. Moreover, they might be combined with other biomaterials, acting as efficient dressings with anti-inflammatory, antioxidant, and antibacterial properties for rapid recovery of chronic wounds.
·mdpi.com·
In Vitro Wound-Healing Potential of Phenolic and Polysaccharide Extracts of Aloe vera Gel
Essential Sugars - Innvista
Essential Sugars - Innvista
Pages Introduction Dictionary Economic Alternatives Fucose Galactose Glucosamine Glucose Mannose N-Acetylneuraminic Acid Nacetylgalactosamine Sugar Nutrien
·web.archive.org·
Essential Sugars - Innvista
Sulfur – Insulin – Diabetes
Sulfur – Insulin – Diabetes
Insulin’s functionality is significantly influenced by its structural integrity, which is maintained by disulfide bonds. Heavy metals like mercury, uranium, and lead attack sensitive sulfur bonds. The science of mercury toxicity shows us that mercurials are highly attracted to sulfhydryls or thiols. The mercury atom or molecule will tend to bind with any molecule present... View Article
·drsircus.com·
Sulfur – Insulin – Diabetes
Hemp - Innvista
Hemp - Innvista
Pages Abstracts Articles Bibliography Common Hemp Crop Pests Growing Hemp Harvesting Hemp Hemp Around the World Hemp Biology Hemp Food Storage Hemp Oil Hemp Products Information Hemp Seed Protein Hemp Seeds Hemp Seeds as Medicine Hemp Species History of Hemp Industrial Hemp Paper Schlichten Papers
·web.archive.org·
Hemp - Innvista
Daniel: Prophet or Phony? - YouTube
Daniel: Prophet or Phony? - YouTube
The Bible says Daniel was written in the 6th century BC. Critics say Daniel was written in the 2nd century BC, and then the author pretended to predict events that had already come to pass. Was Daniel a pretender, or a prophet who was given visions of the future by the God of Scripture? Check out the top ten archaeological discoveries related to Daniel!
·youtube.com·
Daniel: Prophet or Phony? - YouTube
Exhaustive proof that dinosaurs lived recently - YouTube
Exhaustive proof that dinosaurs lived recently - YouTube
Enjoy this 5-minute clip from our movie "The Ark and the Darkness" that shows clear evidence for dinosaurs living recently and killed just thousands of years ago in the Genesis Flood. The second part of this video provides a more technical explanation about dinosaur soft tissue. See more here: www.genesisapologetics.com/dinosaurs
·youtube.com·
Exhaustive proof that dinosaurs lived recently - YouTube
BREAKING: Hezbollah Rockets SLAM Israel; West Bank Designated ACTIVE Combat Zone | TBN Israel - YouTube
BREAKING: Hezbollah Rockets SLAM Israel; West Bank Designated ACTIVE Combat Zone | TBN Israel - YouTube
TBN Israel's Yair Pinto reports on the Israel-Hamas War. Pinto reports that the IDF has destroyed several new Hamas terror tunnels in Gaza, one in which a Hamas tunnel warfare manual was found. In Judea and Samaria, the IDF continues its antiterrorism operations as Iran attempts to ignite another front there against Israel. Stay up-to-date with the latest developments here on TBN Israel. Our sponsor for today's video, The Friends of Israel Gospel Ministry, is raising contributions to provide essential aid and offer training and specialized gear for volunteers and medical responders. Every Donation you make is going directly for the effort of saving lives here in Israel. Please visit their page at: WWW.FOI.ORG Please join us in praying for the peace of Israel and Jerusalem. TBN Israel is creating cutting-edge content that tells the continuing, multi-faceted narrative of Israel. And it all happens through partners like you. Your financial support enables TBN Israel to produce engaging, one-of-a-kind programming that educates viewers around the world about this land and people so loved by God. Donate today: https://www.tbn.org/israel This video was brought to you by TBN Networks®. Get weekly summaries of the top news from Israel and the Middle East delivered to your inbox: https://tbnisrael.com/newsletter-signup WATCH full episodes of Insights: Israel & The Middle East for free on TBN+: https://www.tbnplus.com/c/s/8Bg6gKhf SUBSCRIBE: https://www.youtube.com/channel/UC73H5p3GP8b5N1f3hozIXyQ?sub_confirmation=1 FOLLOW US: TBN Israel Instagram: https://www.instagram.com/tbnisrael/​ TBN Israel Facebook: https://www.facebook.com/tbnisrael/ #israel #iran #hezbollah #hamas #israelwar #israelnews #tbnisrael
·youtube.com·
BREAKING: Hezbollah Rockets SLAM Israel; West Bank Designated ACTIVE Combat Zone | TBN Israel - YouTube