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The gut microbiome and cardiovascular disease: current knowledge and clinical potential | American Journal of Physiology-Heart and Circulatory Physiology
The gut microbiome and cardiovascular disease: current knowledge and clinical potential | American Journal of Physiology-Heart and Circulatory Physiology
Cardiovascular disease (CVD) is the leading cause of death worldwide. The human body is populated by a diverse community of microbes, dominated by bacteria, but also including viruses and fungi. The largest and most complex of these communities is located in the gastrointestinal system and, with its associated genome, is known as the gut microbiome. Gut microbiome perturbations and related dysbiosis have been implicated in the progression and pathogenesis of CVD, including atherosclerosis, hypertension, and heart failure. Although there have been advances in the characterization and analysis of the gut microbiota and associated bacterial metabolites, the exact mechanisms through which they exert their action are not well understood. This review will focus on the role of the gut microbiome and associated functional components in the development and progression of atherosclerosis. Potential treatments to alter the gut microbiome to prevent or treat atherosclerosis and CVD are also discussed.
·journals.physiology.org·
The gut microbiome and cardiovascular disease: current knowledge and clinical potential | American Journal of Physiology-Heart and Circulatory Physiology
Essential Sugars - Innvista
Essential Sugars - Innvista
Pages Introduction Dictionary Economic Alternatives Fucose Galactose Glucosamine Glucose Mannose N-Acetylneuraminic Acid Nacetylgalactosamine Sugar
·innvista.com·
Essential Sugars - Innvista
ENVIRONMENTAL MEDICINE WITH BARRY SMELTZER - The HighWire
ENVIRONMENTAL MEDICINE WITH BARRY SMELTZER - The HighWire
Holistic practitioner, Barry Smeltzer, MPAS, PA-C, FAAEM, discusses his journey from conventional medicine after healing his son from autism with the help of his wife using alternative treatments. Hear about his Holistic Medical Clinic, Healing Provisions, and the upcoming annual conference with the American Academy of Environmental Medicine in San Antonio. POSTED: October 6, 2023
·thehighwire.com·
ENVIRONMENTAL MEDICINE WITH BARRY SMELTZER - The HighWire
TROUBLING STUDY SHOWS HEART DAMAGE IN VACCINATED - The HighWire
TROUBLING STUDY SHOWS HEART DAMAGE IN VACCINATED - The HighWire
A new study has detected heart inflammation in all mRNA vaccinated patients who were undergoing routine medical checkups for other reasons. If replicated, the findings could upend the idea of rare myocarditis after COVID vaccination.
·thehighwire.com·
TROUBLING STUDY SHOWS HEART DAMAGE IN VACCINATED - The HighWire
! 1 ESTEEMED JAPANESE PROFESSOR SOUNDS THE ALARM ON OMICRON - The HighWire
! 1 ESTEEMED JAPANESE PROFESSOR SOUNDS THE ALARM ON OMICRON - The HighWire
Japanese researcher, Dr. Takayuki Miyazawa, took to the streets of Japan in an historic effort to convey information about research showing the Omicron variant may have been artificially synthesized. Learn how The HighWire has been leading the worldwide media coverage of this important issue. POSTED: October 9, 2023
·thehighwire.com·
! 1 ESTEEMED JAPANESE PROFESSOR SOUNDS THE ALARM ON OMICRON - The HighWire
Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer | European Journal of Epidemiology
Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer | European Journal of Epidemiology
European Journal of Epidemiology - Light-at-night triggers the decline of pineal gland melatonin biosynthesis and secretion and is an IARC-classified probable breast-cancer risk factor. We applied...
·link.springer.com·
Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer | European Journal of Epidemiology
Lion's Mane Powder - PureBulk, Inc.
Lion's Mane Powder - PureBulk, Inc.
Supplement Facts & Directions Supplement Facts Serving Size: 500 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* Lion's Mane Extract (Hericium erinaceus) (sporocarp) 500 mg       (Standardized to ≥30% Polysaccharide) † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive. Please call for exact numbers. Supplement Facts Serving Size: 1 Capsule Servings Per Container: Varies Amount Per Serving % Daily Value* Lion's Mane Extract (Hericium erinaceus) (sporocarp) 500 mg (Standardized to ≥30% Polysaccharide) † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive. Please call for exact numbers. Supplement Facts Serving Size: 1 Capsule Servings Per Container: Varies Amount Per Serving % Daily
·purebulk.com·
Lion's Mane Powder - PureBulk, Inc.
Neuronal Health – Can Culinary and Medicinal Mushrooms Help? - PMC
Neuronal Health – Can Culinary and Medicinal Mushrooms Help? - PMC
Hericium erinaceus a culinary and medicinal mushroom is a well established candidate for brain and nerve health. Ganoderma lucidum, Grifola frondosa and Sarcodon scabrosus have been reported to have neurite outgrowth and neuronal health benefits. The ...
·ncbi.nlm.nih.gov·
Neuronal Health – Can Culinary and Medicinal Mushrooms Help? - PMC
Functional Nutrients for Epilepsy - PMC
Functional Nutrients for Epilepsy - PMC
Epilepsy is a common neurological disorder of which seizures are a core symptom. Approximately one third of epileptic patients are resistant to antiepileptic drugs and therefore require alternative therapeutic options. Dietary and nutritional supplements ...
·ncbi.nlm.nih.gov·
Functional Nutrients for Epilepsy - PMC
Senolytic drugs: from discovery to translation - PubMed
Senolytic drugs: from discovery to translation - PubMed
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin and Navitoclax were discovered using a hypothesis-driven approach. SC accumulate with ageing and at causal sites of multiple chronic disorders, including diseases acco …
·pubmed.ncbi.nlm.nih.gov·
Senolytic drugs: from discovery to translation - PubMed
CO2 Medicine & Bath Bombing Your Way to Health
CO2 Medicine & Bath Bombing Your Way to Health
Ladies, you are looking at the power of carbon dioxide medicine. This is the same woman before, after one year and after two years of daily application of a carbon dioxide gel that is applied directly to the face. What this will do to the skin this will do to one’s internal tissues when... View Article
·drsircus.com·
CO2 Medicine & Bath Bombing Your Way to Health
! One size does not fit all – Trehalose metabolism by Clostridioides difficile is variable across the five phylogenetic lineages | Microbiology Society
! One size does not fit all – Trehalose metabolism by Clostridioides difficile is variable across the five phylogenetic lineages | Microbiology Society
Clostridioides difficile , the leading cause of antibiotic-associated diarrhoea worldwide, is a genetically diverse species which can metabolise a number of nutrient sources upon colonising a dysbiotic gut environment. Trehalose, a disaccharide sugar consisting of two glucose molecules bonded by an α 1,1-glycosidic bond, has been hypothesised to be involved in the emergence of C. difficile hypervirulence due to its increased utilisation by the RT027 and RT078 strains. Here, growth in trehalose as the sole carbon source was shown to be non-uniform across representative C. difficile strains, even though the genes for its metabolism were induced. Growth in trehalose reduced the expression of genes associated with toxin production and sporulation in the C. difficile R20291 (RT027) and M120 (RT078) strains in vitro, suggesting an inhibitory effect on virulence factors. Interestingly, the R20291 TreR transcriptional regulatory protein appeared to possess an activator function as its DNA-binding ability was increased in the presence of its effector, trehalose-6-phosphate. Using RNA-sequencing analysis, we report the identification of a putative trehalose metabolism pathway which is induced during growth in trehalose: this has not been previously described within the C. difficile species. These data demonstrate the metabolic diversity exhibited by C. difficile which warrants further investigation to elucidate the molecular basis of trehalose metabolism within this important gut pathogen.
·microbiologyresearch.org·
! One size does not fit all – Trehalose metabolism by Clostridioides difficile is variable across the five phylogenetic lineages | Microbiology Society
Fucoidan alleviates Salmonella-induced inflammation and mortality by modulating gut microbiota and metabolites, protecting intestinal barrier, and inhibiting NF-κB pathway - ScienceDirect
Fucoidan alleviates Salmonella-induced inflammation and mortality by modulating gut microbiota and metabolites, protecting intestinal barrier, and inhibiting NF-κB pathway - ScienceDirect
Salmonella typhimurium (ST) poses a serious threat to host health, and the adverse effects of antibiotic treatment necessitate the urgent search for i…
·sciencedirect.com·
Fucoidan alleviates Salmonella-induced inflammation and mortality by modulating gut microbiota and metabolites, protecting intestinal barrier, and inhibiting NF-κB pathway - ScienceDirect
RESEARCHERS CREATE AEROSOLIZED MRNA "VACCINE"
RESEARCHERS CREATE AEROSOLIZED MRNA "VACCINE"
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination Alexandra Suberi et al. Sci Transl Med. 2023. https://pubmed.ncbi.nlm.nih.gov/37585505/ . Injectable mRNA-based vaccines were ins
·rumble.com·
RESEARCHERS CREATE AEROSOLIZED MRNA "VACCINE"