Found 10224 bookmarks
Newest
Symptoms of Iodine Deficiency - YouTube
Symptoms of Iodine Deficiency - YouTube
Think you might be gluten sensitive? Take the quiz: https://www.glutenfreesociety.org/gluten-sensitivity-intolerance-self-test/ Becoming deficient in iodine can cause many issues, including: - Failure to thrive, as well as growth and development issues in the brain and nervous system of infants (due to maternal iodine deficiency in utero as well as outside the womb) - Cretinism or mental retardation in young children - Decreased fertility rates in men and women - Goiter, or enlargement of the thyroid gland, leading to pressure on the larynx and vocal cords and trouble swallowing - Fatigue, brain fog, and muscle pain - Fibrocystic breast disease and extreme breast tenderness - Death Because many of these are the same symptoms associated with thyroid problems, doctors will often prescribe medication to ease these symptoms without truly getting to the root of the problem. It is best to request testing for an iodine deficiency prior to accepting medication and receiving a potentially incorrect treatment. To connect with Dr. Osborne visit: On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterOsborne/ Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world’s leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527
·youtube.com·
Symptoms of Iodine Deficiency - YouTube
16 More Reasons Black Seed is 'The Remedy For Everything But Death'
16 More Reasons Black Seed is 'The Remedy For Everything But Death'
Known since ancient times as a 'remedy for everything but death,' an increasingly vast body of scientific research reveals that it is indeed one of nature's most potent and versatile healing agents
·greenmedinfo.com·
16 More Reasons Black Seed is 'The Remedy For Everything But Death'
Second Follow-up Patient Interview - Neurological Issues After Vaccination - YouTube
Second Follow-up Patient Interview - Neurological Issues After Vaccination - YouTube
Second Follow-up Patient Interview - Neurological Issues After Vaccination Today we will interview Shaun Barcavage. He is an amazing healthcare professional. He has been struggling with the neurological issues since his vaccination. Shaun has graciously agreed to share his journey with us. If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
·youtube.com·
Second Follow-up Patient Interview - Neurological Issues After Vaccination - YouTube
LIVE WORLD'S LEADING PHYSICIANS AND SCIENTISTS HOLD GLOBAL COVID SUMMIT - The HighWire
LIVE WORLD'S LEADING PHYSICIANS AND SCIENTISTS HOLD GLOBAL COVID SUMMIT - The HighWire
The Global Covid Summit, comprising over 17,000 physicians and scientists, holds a press conference highlighting the Summit’s declaration to “Restore Scientific Integrity.” Speakers include Dr. Robert Malone, Dr. Peter McCullough, Dr. Ryan Cole, Harvey Risch, MD, PhD, Dr. Lynn Fynn, Dr. Mary Talley Bowden, Dr. Richard Urso and more. #GCS #RestoreScientificIntegrity #GlobalCovidSummit
·thehighwire.com·
LIVE WORLD'S LEADING PHYSICIANS AND SCIENTISTS HOLD GLOBAL COVID SUMMIT - The HighWire
Paxlovid Failed to Prevent COVID-19 - YouTube
Paxlovid Failed to Prevent COVID-19 - YouTube
Paxlovid Failed to Prevent COVID-19 If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Paxlovid failed to provide prophylactic protection for the household members of the COVID patients. Let's review the good, the bad, and the ugly of Paxlovid. Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Tuesday, May. 10 2022 DrBeen: Medical Education Online https://www.drbeen.com/ EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 - Full Text View - ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT04960202 Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2118542 Clinical Studies | PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets) https://www.covid19oralrx-hcp.com/clinical-studies?source=google&HBX_PK=s_paxlovid+results&skwid=43700068281649038&gclid=Cj0KCQjwmuiTBhDoARIsAPiv6L_CQ8C5C7AQsXGYtMhZx5rjk7W8pNjd3gdK_Z1BYWY8X7Ifv_-iu5UaAm6-EALw_wcB&gclsrc=aw.ds Paxlovid HCP FS 04142022 https://www.fda.gov/media/155050/download EUA 105 Pfizer Paxlovid DHCP 04142022 https://www.fda.gov/media/155071/download Pfizer Shares Top-Line Results from Phase 2/3 EPIC-PEP Study of PAXLOVID™ for Post-Exposure Prophylactic Use | Pfizer https://www.pfizer.com/news/press-release/press-release-detail/pfizer-shares-top-line-results-phase-23-epic-pep-study Paxlovid Mouth Is Real—And Gross - The Atlantic https://www.theatlantic.com/health/archive/2022/05/pfizer-paxlovid-covid-pill-side-effects/629772/ Pfizer says COVID treatment Paxlovid fails to prevent infection of household members | Reuters https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-says-covid-treatment-paxlovid-fails-prevent-infection-household-members-2022-04-29/ FDA warns Paxlovid as COVID treatment option https://www.fiercepharma.com/pharma/fda-rebukes-pfizers-suggestion-take-more-paxlovid-if-covid-19-symptoms-return Covid-19 cases that return after Paxlovid antiviral treatment puzzle doctors - CNN https://www.cnn.com/2022/04/27/health/paxlovid-covid-rebound/index.html FDA EUA Note for Paxlovid https://www.fda.gov/media/155194/download
·youtube.com·
Paxlovid Failed to Prevent COVID-19 - YouTube
Gut Microbiome Disrupted by SARS-COV-2 - Italian Study (Dr. Carlo Brogna) - YouTube
Gut Microbiome Disrupted by SARS-COV-2 - Italian Study (Dr. Carlo Brogna) - YouTube
Yes GUT Microbiome Is Disrupted by SARS-COV-2 - Italian Study (Dr. Carlo Brogna) This study offers a new possibility to understand severity, transmission, and therapeutics for SARS-COV-2. Let's review. If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Monday, May. 9 2022 DrBeen: Medical Education Online https://www.drbeen.com/ MDPI | About https://www.mdpi.com/about Vaccines | Free Full-Text | Could SARS-CoV-2 Have Bacteriophage Behavior or Induce the Activity of Other Bacteriophages? https://www.mdpi.com/2076-393X/10/5/708 Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles | Technology Networks https://www.technologynetworks.com/immunology/articles/lytic-vs-lysogenic-understanding-bacteriophage-life-cycles-308094 Polio vaccine - Wikipedia https://en.wikipedia.org/wiki/Polio_vaccine
·youtube.com·
Gut Microbiome Disrupted by SARS-COV-2 - Italian Study (Dr. Carlo Brogna) - YouTube
Key Body Functions of Iodine - YouTube
Key Body Functions of Iodine - YouTube
Think you might be gluten sensitive? Take the quiz: https://www.glutenfreesociety.org/gluten-sensitivity-intolerance-self-test/ Iodine is critical to thyroid health. It is necessary to produce T3 and T4 which are thyroid hormones. These not only regulate growth, but they are vital for metabolism, generating energy, and communicating with DNA about how cells are supposed to grow, heal, and repair. T3 is an active thyroid hormone with three molecules of iodine, while T4 is inactive and contains four molecules. Once TSH (thyroid-stimulating hormone) is produced by the brain, it travels to the thyroid telling it to produce T4 and to trap more of this nutrient in the diet in order to produce T3. T3 then communicates to DNA to upregulate the metabolism. This process also requires selenium, tyrosine (an amino acid), and vitamins B2 and C. Without all of these nutrients, and without iodine, this process will not work correctly – and neither will the thyroid. To connect with Dr. Osborne visit: On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterOsborne/ Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world’s leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527
·youtube.com·
Key Body Functions of Iodine - YouTube
Do You Want To Live Forever
Do You Want To Live Forever
If you are interested in living forever, know that enduring youth can be yours with enough oxygen. Dr. Arthur C. Guyton says, “All chronic pain, suffering, and diseases are caused by a lack of oxygen at the cell level.” Insufficient oxygen means insufficient biological energy resulting in anything from mild fatigue to life-threatening disease. “Oxygen... View Article
·drsircus.com·
Do You Want To Live Forever
Does the COVID Jab Kill More People Than It Saves GreenMedInfo
Does the COVID Jab Kill More People Than It Saves GreenMedInfo
According to U.S. Centers for Disease Control and Prevention data, more than 1 million excess deaths have been recorded since the COVID-19 pandemic began two years ago and cannot be explained by COVID
·greenmedinfo.com·
Does the COVID Jab Kill More People Than It Saves GreenMedInfo
Toxins in The Water ~ Fluoride is Poison and How to Detox Your Body - YouTube
Toxins in The Water ~ Fluoride is Poison and How to Detox Your Body - YouTube
As the key to life and the basis for all cellular health, clean water is an absolute necessity. 90% of people are dehydrated and many consume tap water which is highly contaminated with fluoride, chlorine, arsenic, pesticides, pharmaceutical medications, bacteria, heavy metals, and more. Learn about the issues and solutions in this 10-minute clip from Dr. Group's 2015 seminar "The Secret to Health." Dr. Group will expose the effects of toxic beverages like tap water, soda, processed cow's milk, and more while teaching you to detoxify your internal environment for a healthier and more empowered life. –––––––––––– Learn more about Dr. Group's coursework by becoming a member of The Global Healing Institute ~ https://globalhealinginstitute.org/ Member Benefits: Join any course and you’ll be invited to Q&As, exclusive interviews with leading medical professionals, healing summits, wellness seminars, and much more. BECOME A MEMBER NOW ➤➤ https://globalhealinginstitute.org/ *Renovations occurring until May 18th, 2022. ––––––––––––– Follow Dr. Group on social media! ➤➤ Uncensored TRUTH on telegram - https://t.me/drgroupofficial https://www.brighteon.com/channels/dr... https://www.instagram.com/drgroupoffi... https://www.facebook.com/DrEdwardGroup https://www.tiktok.com/@drgroupoffical https://twitter.com/dr_edwardgroup ––––––––––––– Website ➤➤ https://DrGroup.com/ ––––––––––––– Dr. Edward Group III, DC, NP, DACBN, DCBCN, DABFM is the founder and CEO of Global Healing. He assumes a hands-on approach in producing new and advanced life-changing products and information to help you maintain a clean body and live a healthy lifestyle. It's the Global Healing mission to bring back good health, positive thinking, happiness, and love. ––––––––––––– The statements expressed by Dr. Group, Global Healing, and its partners are published for educational and informational purposes only and are not intended as a diagnosis, treatment, or as a substitute for professional medical advice.
·youtube.com·
Toxins in The Water ~ Fluoride is Poison and How to Detox Your Body - YouTube
Site-specific analysis of the SARS-CoV-2 glycan shield - PMC
Site-specific analysis of the SARS-CoV-2 glycan shield - PMC
The emergence of the betacoronavirus, SARS-CoV-2 that causes COVID-19, represents a significant threat to global human health. Vaccine development is focused on the principal target of the humoral immune response, the spike (S) glycoprotein, that mediates ...
·ncbi.nlm.nih.gov·
Site-specific analysis of the SARS-CoV-2 glycan shield - PMC
Hormone Disruption in Long COVID - YouTube
Hormone Disruption in Long COVID - YouTube
Hormone Disruption in Long COVID US scientists present the potential mechanism behind the chronic fatigue syndrome after COVID-19. Let's review their article. If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Thursday, May. 5 2022 16:39 PM To copy this list, type [Ctrl] A, then type [Ctrl] C. COVID-19 and chronic fatigue syndrome: An endocrine perspective - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641402/ Tissue expression of ACE2 - Summary - The Human Protein Atlas https://www.proteinatlas.org/ENSG00000130234-ACE2/tissue Post-acute COVID-19 syndrome - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893149/ COVID-19 and chronic fatigue syndrome: An endocrine perspective - ScienceDirect https://www.sciencedirect.com/science/article/pii/S2214623721000363#! Physiology, Cortisol - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK538239/ Adrenal Insufficiency (Addison's Disease) | Johns Hopkins Medicine https://www.hopkinsmedicine.org/health/conditions-and-diseases/underactive-adrenal-glands--addisons-disease Causes of Addison's disease: Adrenal gland disruption and others https://www.medicalnewstoday.com/articles/186235#surgery
·youtube.com·
Hormone Disruption in Long COVID - YouTube
Trehalose induces B cell autophagy to alleviate myocardial injury via the AMPKULK1 signalling pathway in acute viral myocarditis induced by Coxsackie virus B3 - PubMed
Trehalose induces B cell autophagy to alleviate myocardial injury via the AMPKULK1 signalling pathway in acute viral myocarditis induced by Coxsackie virus B3 - PubMed
Viral myocarditis (VMC) is the main cause of sudden acute heart failure and cardiac death in adolescents; however, treatment for VMC is limited. Trehalose is a natural non-reductive disaccharide that protects against cardiovascular diseases by inducing autophagy. The protective effect of trehalose o …
·pubmed.ncbi.nlm.nih.gov·
Trehalose induces B cell autophagy to alleviate myocardial injury via the AMPKULK1 signalling pathway in acute viral myocarditis induced by Coxsackie virus B3 - PubMed
The Effect of Gum Acacia on Post-Prandial Glucose and Insulin Levels in Healthy Subjects
The Effect of Gum Acacia on Post-Prandial Glucose and Insulin Levels in Healthy Subjects
This double-blind, controlled, randomized, three-way cross-over study evaluates the effect of 40 g (D1 group) and 20 g (D2 group) of acacia gum (AG) versus no treatment (NT group) on post-prandial glucose (PPG) levels in normal-weight and overweight subjects. Additionally, post-prandial insulin (PPI) levels as well as the safety and tolerability of gum acacia were assessed. 35 healthy subjects aged 25 - 60 years, body mass index 18.5 kg/m2 - 29.9 kg/m2, received one treatment of 20 g, 40 g, or 0 g of AG each. Glucose and insulin values were determined at -15 min and prior to the intake (time “0”) as well as 15, 30, 45, 60, 90 120, and 180 min after the “0 min” blood draw. The mean PPG levels were lower (34% in D1 group, p = 0.003; 35% in D2 group, p = 0.005) than in the NT group. PPI concentration was statistically significantly lower at all time points except baseline in both treatment groups compared to NT groups. Global benefit and tolerability were rated as “very good” or “good” by 100% of subjects in the treatment groups. This study provides robust evidence of the significant benefits of AG consumption on PPG and PPI levels in healthy subjects. Moreover, very good tolerability was demonstrated.
·scirp.org·
The Effect of Gum Acacia on Post-Prandial Glucose and Insulin Levels in Healthy Subjects
Gluten Transit Time - YouTube
Gluten Transit Time - YouTube
Think you might be gluten sensitive? Take the quiz: https://www.glutenfreesociety.org/gluten-sensitivity-intolerance-self-test/ My favorite supplements to support detoxing from gluten: Detox C: http://glutenfreesociety.org/DetoxCPowder Gluten Shield: http://glutenfreesociety.org/GlutenShield The initial short term discomfort is generally resolved once the ingested gluten has moved through your digestive tract. The time it takes from mouth to bowel movement is referred to as transit time. Transit time can vary from person to person for a variety of different reasons including, the health and function of the gut, liver, and pancreas. In addition, different types of food take different amounts of time to pass through the digestive tract. For example, simple carbohydrates take less time to digest compared to protein or fiber-rich foods. Transit time is also influenced by a number of other factors, including psychological stress, gender, exercise, sleep, hydration, etc. While you may feel better after a couple days following gluten exposure, there is a lot more happening behind the scenes that you may not be aware of. Ingesting gluten can trigger IgA and IgG antibodies which will then cause leaky gut or intestinal hyperpermeability. The breach of the gut barrier allows toxins to flood into your bloodstream causing systemic tissue damage and inflammation. A number of factors will determine how your body recovers from the “unseen” damage caused by gluten exposure. Research has suggested that the half life of IgA gluten antibodies is about two months and the half life of IgG antibodies is 30-60 days. Translation: it can take 4 months to clear out the antibodies. This means that antibody induced damage can go on for a minimum of two months. However, damage may last far longer, depending on other factors, like the overall state of your gut health, other pre-existing health conditions, your nutritional status, and how many gluten exposures you subject yourself to. In addition to the challenges associated with antibodies that present from ingestion of gluten, research has also shown that the mucosal lining of the intestine does not recover well, even when a gluten free diet is implemented. Specifically, the study notes that mucosal recovery was absent in a substantial portion of adults with celiac disease after treatment with a gluten free diet. This underscores even more how important it is to check food labels, confirm how food was prepared if not by you, and do your research on the testing and practices of any company who makes your food. To connect with Dr. Osborne visit: On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterOsborne/ Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world’s leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527
·youtube.com·
Gluten Transit Time - YouTube
Kellman Wellness Center Functional and Holistic Medicine NYC
Kellman Wellness Center Functional and Holistic Medicine NYC
Kellman Wellness Center is the premiere functional and holistic medical practice in New York City, NY. In-person and telemedicine appointments available. ☎ (212) 717-1118.
·kellmancenter.com·
Kellman Wellness Center Functional and Holistic Medicine NYC
Trehalose increases tomato drought tolerance, induces defenses, and increases resistance to bacterial wilt disease
Trehalose increases tomato drought tolerance, induces defenses, and increases resistance to bacterial wilt disease
Ralstonia solanacearum causes bacterial wilt disease, leading to severe crop losses. Xylem sap from R. solanacearum-infected tomato is enriched in the disaccharide trehalose. Water-stressed plants also accumulate trehalose, which increases drought tolerance via abscisic acid (ABA) signaling. Because R. solanacearum-infected plants suffer reduced water flow, we hypothesized that bacterial wilt physiologically mimics drought stress, which trehalose could mitigate. We found that R. solanacearum-infected plants differentially expressed drought-associated genes, including those involved in ABA and trehalose metabolism, and had more ABA in xylem sap. Consistent with this, treating tomato roots with ABA reduced both stomatal conductance and stem colonization by R. solanacearum. Treating roots with trehalose increased xylem sap ABA and reduced plant water use by lowering stomatal conductance and temporarily improving water use efficiency. Trehalose treatment also upregulated expression of salicylic acid (SA)-dependent tomato defense genes; increased xylem sap levels of SA and other antimicrobial compounds; and increased bacterial wilt resistance of SA-insensitive NahG tomato plants. Additionally, trehalose treatment increased xylem concentrations of jasmonic acid and related oxylipins. Finally, trehalose-treated plants were substantially more resistant to bacterial wilt disease. Together, these data show that exogenous trehalose reduced both water stress and bacterial wilt disease and triggered systemic disease resistance, possibly through a Damage Associated Molecular Pattern (DAMP) response pathway. This suite of responses revealed unexpected linkages between plant responses to biotic and abiotic stress and suggested that R. solanacearum-infected plants increase trehalose to improve water use efficiency and increase wilt disease resistance. The pathogen may degrade trehalose to counter these efforts. Together, these results suggest that treating tomatoes with exogenous trehalose could be a practical strategy for bacterial wilt management.
·journals.plos.org·
Trehalose increases tomato drought tolerance, induces defenses, and increases resistance to bacterial wilt disease