2016

The latest research reveals that there are microbes that actually live within cancerous tumors, challenging accepted dogma.

Iranian Registry of Clinical Trials (IRCT) Id: IRCT20210508051223N1, Registration date: 26 July 2021.

Cellular and Molecular Neurobiology - Spinal cord injury (SCI) leads to long-term and permanent motor dysfunctions, and nervous system abnormalities. Injury to the spinal cord triggers a signaling...

Did you know that magnesium has the power to both relieve your pain and help you reduce inflammation throughout your body?

Fucoidan from brown seaweeds has several biological effects, including preserving intestinal integrity. To investigate the intestinal protective properties of high molecular weight fucoidan (HMWF) from Undaria pinnatifida on intestinal integrity dysfunction caused by methylglyoxal-derived hydroimidazolone-1 (MG-H1), one of the dietary advanced-glycation end products (dAGEs) in the human-colon carcinoma-cell line (Caco-2) cells and ICR mice. According to research, dAGEs may damage the intestinal barrier by increasing gut permeability. The findings of the study showed that HMWF + MG-H1 treatment reduced by 16.8% the amount of reactive oxygen species generated by MG-H1 treatment alone. Furthermore, HMWF + MGH-1 treatment reduced MG-H1-induced monolayer integrity disruption, as measured by alterations in transepithelial electrical resistance (135% vs. 75.5%) and fluorescein isothiocyanate incorporation (1.40 × 10−6 cm/s vs. 3.80 cm/s). HMWF treatment prevented the MG-H1-induced expression of tight junction markers, including zonula occludens-1, occludin, and claudin-1 in Caco-2 cells and mouse colon tissues at the mRNA and protein level. Also, in Caco-2 and MG-H1-treated mice, HMWF plays an important role in preventing receptor for AGEs (RAGE)-mediated intestinal damage. In addition, HMWF inhibited the nuclear factor kappa B activation and its target genes leading to intestinal inflammation. These findings suggest that HMWF with price competitiveness could play an important role in preventing AGEs-induced intestinal barrier dysfunction.

Metabolic epilepsy is a metabolic abnormality which is associated with an increased risk of epilepsy development in affected individuals. Commonly used antiepileptic drugs are typically ineffective against metabolic epilepsy as they do not address its root cause. Presently, there is no review available which summarizes all the treatment options for metabolic epilepsy. Thus, we systematically reviewed literature which reported on the treatment, therapy and management of metabolic epilepsy from four databases, namely PubMed, Springer, Scopus and ScienceDirect. After applying our inclusion and exclusion criteria as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we reviewed a total of 43 articles. Based on the reviewed articles, we summarized the methods used for the treatment, therapy and management of metabolic epilepsy. These methods were tailored to address the root causes of the metabolic disturbances rather than targeting the epilepsy phenotype alone. Diet modification and dietary supplementation, alone or in combination with antiepileptic drugs, are used in tackling the different types of metabolic epilepsy. Identification, treatment, therapy and management of the underlying metabolic derangements can improve behavior, cognitive function and reduce seizure frequency and/or severity in patients.

Cerebrovascular disease, a frequent complication of hypertension, is a major public health issue for which novel therapeutic and preventive approaches…

About Dr V Dr. V Speaks 7 Essentials Coaches Shop Coaching Programs Private Coaching Success Stories Blog Podcasts Recipes Retreats Conquer Together Sarasota Contact is ... Read More

DuckDuckGo. Privacy, Simplified.

Think you might be gluten sensitive? Take the quiz: https://www.glutenfreesociety.org/gluten-sensitivity-intolerance-self-test/ Seems like gluten is everywhere! But is gluten in your medication? There might be. Gluten is a common filler in many prescription and over the counter medications. A recent research report found that almost 20% of medicine contained gluten. The study also found that the inactive ingredients in drugs contained sugar, dairy, and food dyes. Researchers are worried about the potential for drug reactions based on this new information. To connect with Dr. Osborne visit: On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterOsborne/ Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world’s leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527

(NaturalHealth365) Recent study calls into question the safety of regularly using a common painkiller. Discover what the study found.

MOLECULAR MECHANISMS OF FUNCTIONAL FOOD Comprehensive resource for understanding state-of-the-art mechanisms behind food health effects This book provides information on the development and validation of functional foods towards their market and industrial application. It covers the available information on developments, efficacy, and testing and safety, while demonstrating the proven or potential effects of food on health and disease. With contributions from the foremost experts in the field, this book will bring readers up to speed on the state of the art in the mechanisms behind food health effects, from their physiological bases to their conception, current uses, and future developments. Sample topics covered by the authors include: The molecular mechanisms of action of antioxidant fibers, prebiotics, ginger, and cinnamon Saffron, a functional food with potential molecular effects Pseudocereals, ancestral grains that can serve as a source of bioactive compounds for functional foods Molecular effects of future functional foods – psychobiotics, chronobiotics, hempseed, opuntia, common and carioca beans, coffee and cocoa by-products Food industry professionals, government workers involved in projects related to food, and students in programs of study related to food can use this book as an up-to-date reference to fully understand the effects that many common and uncommon foods have on humans.

Peptide Therapy INTENSIVE CERTIFICATION Real Clinical ExperienceNot Textbook Answers BEGIN Application https://youtu.be/C0FbK6obi8o We Help Providers Improve Patient Outcomes With Peptide Therapy Peptide Therapy is changing the way we practice medicine. If you’re not including peptides into your protocols, you could be missing an incredible opportunity to grow your practice and improve the outcomes of your … Peptide Certification Read More »

Lancet Commission Report on COVID - The Good, The Bad, And The Ugly Interesting beginning of a new era of finger pointing and further bias in the name of commissions. Let's see what Lancet commission has to say. https://twitter.com/thelancet/status/1570178509418692608?s=46&t=LabGZht-qamyoqQjGJrEjQ Page 4. United States and other countries. URL list from Friday, Sep. 16 2022 The Lancet Commission on lessons for the future from the COVID-19 pandemic - The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01585-9/fulltext The Lancet Commission on lessons for the future from the COVID-19 pandemic https://www.thelancet.com/action/showPdf?pii=S0140-6736%2822%2901585-9 WHO responds to The Lancet COVID-19 Commission https://www.who.int/news/item/15-09-2022-who-responds-to-the-lancet-covid-19-commission Timeline of WHO's response to COVID-19 https://www.who.int/emergencies/diseases/novel-coronavirus-2019/interactive-timeline#! WHO Declares COVID-19 a Pandemic - PubMed https://pubmed.ncbi.nlm.nih.gov/32191675/#:~:text=The%20World%20Health%20Organization%20(WHO,a%20global%20pandemic%20(1). Mortality Analyses - Johns Hopkins Coronavirus Resource Center https://coronavirus.jhu.edu/data/mortality People at The Lancet https://www.thelancet.com/lancet-people Richard Horton (editor) - Wikipedia https://en.wikipedia.org/wiki/Richard_Horton_(editor) CDC director Rochelle Walensky visits #WashUMed - YouTube https://www.youtube.com/watch?v=I_hYgIpxM4A DrScott on Twitter: "People know we have to get a new flu vaccine every year to deal with variations of influenza virus. Wilensky is saying that nobody thought new variants might not be susceptible to the vaccine? Oh yes we were We were just CANCELED!! https://t.co/wYJbsHtnpn" / Twitter https://twitter.com/drscott_atlanta/status/1499934047849660419?s=21 Covid-19: How Much Herd Immunity is Enough? - The New York Times https://www.nytimes.com/2020/12/24/health/herd-immunity-covid-coronavirus.html

Combined treatment is a promising anticancer strategy for improving antiproliferation compared with a single treatment but is limited by adverse side effects on normal cells. Fucoidan (FN), a brown-algae-derived polysaccharide safe food ingredient, exhibits preferential function for antiproliferation to oral cancer but not normal cells. Utilizing the preferential antiproliferation, the impacts of FN in regulating ultraviolet C (UVC) irradiation were assessed in oral cancer cells. A combined treatment (UVC/FN) reduced cell viability of oral cancer cells (Ca9-22 and CAL 27) more than single treatments (FN or UVC), i.e., 53.7%/54.6% vs. 71.2%/91.6%, and 89.2%/79.4%, respectively, while the cell viability of UVC/FN treating on non-malignant oral (S–G) was higher than oral cancer cells, ranging from 106.0 to 108.5%. Mechanistically, UVC/FN preferentially generated higher subG1 accumulation and apoptosis-related inductions (annexin V, caspases 3, 8, and 9) in oral cancer cells than single treatments. UVC/FN preferentially generated higher oxidative stress than single treatments, as evidenced by flow cytometry-detecting reactive oxygen species, mitochondrial superoxide, and glutathione. Moreover, UVC/FN preferentially caused more DNA damage (γH2AX and 8-hydroxy-2’-deoxyguanosine) in oral cancer cells than in single treatments. N-acetylcysteine pretreatment validated the oxidative stress effects in these UVC/FN-induced changes. Taken together, FN effectively enhances UVC-triggered antiproliferation to oral cancer cells. UVC/FN provides a promising potential for preferential and synergistic antiproliferation in antioral cancer therapy.

Inflammation and oxidative stress are known to be involved in the pathogenesis of chronic kidney disease in humans, and in chronic renal failure (CRF) in rats. The aim of this work was to study the role of inflammation and oxidative stress in adenine-induced CRF and the effect thereon of the purport …

The microfilaricidal anthelmintic drug ivermectin (IVM) has been used since 1988 for treatment of parasitic infections in animals and humans. The discovery of IVM’s ability to inactivate the eukaryotic importin α/β1 heterodimer ...

Induction of autophagy is a prospective approach to the treatment of neurodegeneration. In the recent decade, trehalose attracted special attention. It is an autophagy inducer with negligible adverse effects and is approved for use in humans according to FDA requirements. Trehalose has a therapeutic …

Glioma, the most predominant primary malignant brain tumor, remains uncured due to the absence of effective treatments. Hence, it is imperative to develop successful therapeutic agents. This study aimed to explore the antitumor effects and mechanisms of ivermectin (IVM) in glioma cells in vitro and …

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. ...

Ivermectin, a dihydro derivative of avermectin (AVM), was introduced into the veterinary, agricultural and aquaculture markets for animal health in 1981. Ivermectin was soon adopted in 1987 as a human medicine that was originally used for the treatment of onchocerciasis, a parasitic infection. Since …

The currently available data suggest that response to treatment with a highly purified, plant-derived CBD oil-based solution can be seen in patients across a broad range of epilepsy disorders and etiologies. The existing evidence can provide preliminary support for additional research.

Cellular medicine combines Functional, Precision, & Integrative Medicine into effective protocols and treatments to improve patient outcomes.