2016

Background: Humans with hypertensive heart disease are more likely to experience heart failure, arrhythmia, myocardial infarction, and sudden death, and it is crucial to treat this condition. Fucoidan (FO) is a natural substance derived from marine algae that has antioxidant and immunomodulatory activities. FO has also been shown to regulate apoptosis. However, whether FO can protect against cardiac hypertrophy is unknown.Methods: We investigated the effect of FO in hypertrophic models in vivo and in vitro. C57BL/6 mice were given an oral gavage of FO (300 mg/kg/day) or PBS (internal control) the day before surgery, followed by a 14-day infusion of Ang II or saline. AC-16 cells were treated with si-USP22 for 4 h and then treated with Ang II (100 nM) for 24 h. Systolic blood pressure (SBP) was recorded, echocardiography was used to assess cardiac function, and pathological changes in heart tissues were assessed by histological staining. Apoptosis levels were detected by TUNEL assays. The mRNA level of genes was assessed by qPCR. Protein expression was detected by immunoblotting.Results: Our data showed that USP22 expression was lowered in Ang II-infused animals and cells, which could promote cardiac dysfunction and remodeling. However, treatment with FO significantly upregulated the expression of USP22 and reduced the incidence of cardiac hypertrophy, fibrosis, inflammation, and oxidative responses. Additionally, FO treatment lowered p53 expression and apoptosis while incre...

(NaturalHealth365) Studies show that regular sauna usage will greatly reduce your risk of Alzheimer's disease. Learn more about this therapy.

(NaturalHealth365) Curcumin is a natural compound shown to offer cancer-protective benefits. Learn more about its medicinal properties.

(NaturalHealth365) Concerns over COVID shot safety mount as the number of post-jab adverse events increase.

So-called "long Covid" is turning out to be a devastating condition for an incredibly large number of individuals around the world. It's been estimated that ...

(NaturalHealth365) Pfizer and BioNTech were recently exposed as fraudulent enterprises willing to bend the truth for financial gain.

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(NaturalHealth365) Major revision to breast cancer screening recommendations ignores risks associated with mammography technology.

For many years, beginning with my book, Brain Maker, I have been discussing the symbiotic bond we share with our microbiome. This connection, while multifaceted, influences our health in ways we …

Rue plant extract may treat COVID-19, according to new clinical research.

Today I talked to the Co-Hosts of Talk Truth, Allan Hunsperger and Corri Hunsperger about my interview with the late Dr. Rashid Buttar. Talk Truth: www.talktruth.ca ☆ We no longer can trust our mainst

Dr Buttar Info Home Page

It is with sadness, yet great appreciation, that we pay tribute to my friend and colleague Dr. Rashid Buttar, who passed away on May 18th.

Aloe vera is a perennial, succulent cacti with cosmopolitan distribution. This plant holds a long history of usages in recovering different

(NaturalHealth365) Scientists explain how sauna bathing can lower the risk of heart disease - without any negative health effects.

(NaturalHealth365) FDA advisory panel green lights highly controversial shot for pregnant women. Learn the details here.

(NaturalHealth365) Substance in rhubarb shows promise as a powerful anticancer agent. Learn how to naturally stop cancer cell growth.

(NaturalHealth365) An MIT professor is speaking out against the mRNA COVID jabs, publicly calling for a halt to the jab program.

Angiogenesis and metastasis represent two challenging targets to combat cancer development in the later stages of its progression. Numerous studies have indicated the important role of natural products in blocking tumor angiogenesis signaling pathways in several advanced tumors. In recent years, the marine polysaccharides fucoidans emerged as promising anticancer compounds showing potent antitumor activity in both in vitro and in vivo models of different types of cancers. The objective of this review is to focus on the antiangiogenic and antimetastatic activities of fucoidans with special emphasis on preclinical studies. Independently from their source, fucoidans inhibit several angiogenic regulators, primarily vascular endothelial growth factor (VEGF). A glance towards fucoidans’ ongoing clinical trials and pharmacokinetic profile is provided to present the main challenges that still need to be addressed for their bench-to-bedside translation.

On May 1st the Centers for Medicare & Medicaid Services announced it will “soon end” its COVID vaccination mandate for healthcare workers.

Without medical breakthroughs, more than 6.4M Australians will be diagnosed with dementia in the next 40 years at a cost of more than $1 trillion. This week I want to discuss several exciting publications that have appeared in the research literature in 2020. It’s not just dementia, other diseases like Alzheimer’s, multiple sclerosis, Parkinson’s, stroke, and even depression are increasingly being linked to something called mitochondrial dysfunction. The literature shows that 2 approaches called: methylene blue and photobiomodulation might be very effective. But why? This issue of mitochondria and its’ link with inflammatory processes has been known for some time. Especially, with respect to how fungal pathogens and environmental fungi seem to induce similar mitochondrial dysfunction in humans. I will look at what’s known about this and then review a paper from 2020 showing that fungi have been found in the brains of people with Parkinson’s disease. This has been termed ‘polymicrobial invasion’ and suggests that some brain disorders are catalyzed by infections. The main paper I want to focus on as part of this Livestream came out on August 14th, 2020, and shows that brain inflammation, cytokine expression, and memory can be actively modulated with a common anti-fungal drug. This is breakthrough research and suggests this treatment could offer real relief in the near term. Join me on the Livestream or on the Podcast to find out which drug offers this potential microbiological benefit and what evidence supports this claim. REFERENCES: Mudarri D, Fisk WJ. Public health and economic impact of dampness and mold [published correction appears in Indoor Air. 2007 Aug;17(4):334]. Indoor Air. 2007;17(3):226-235. doi:10.1111/j.1600-0668.2007.00474.x Yeo, I.J., Yun, J., Son, D.J. et al. Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS. Cell Death Dis 11, 623 (2020). https://doi.org/10.1038/s41419-020-2619-5 Pisa D, Alonso R, Carrasco L. Parkinson's Disease: A Comprehensive Analysis of Fungi and Bacteria in Brain Tissue. Int J Biol Sci 2020; 16(7):1135-1152. doi:10.7150/ijbs.42257. Available from http://www.ijbs.com/v16p1135.htm Yang L, Youngblood H, Wu C, Zhang Q. Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation. Transl Neurodegener. 2020;9(1):19. Published 2020 Jun 1. doi:10.1186/s40035-020-00197-z GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(5):459-480. doi:10.1016/S1474-4422(18)30499-X Hamblin MR. Shining light on the head: Photobiomodulation for brain disorders. BBA Clin. 2016;6:113-124. Published 2016 Oct 1. doi:10.1016/j.bbacli.2016.09.002 Fisher MC, Gurr SJ, Cuomo CA, et al. Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture. mBio. 2020;11(3):e00449-20. Published 2020 May 5. doi:10.1128/mBio.00449-20 Zhang JM, An J. Cytokines, inflammation, and pain. Int Anesthesiol Clin. 2007;45(2):27-37. doi:10.1097/AIA.0b013e318034194e #miconazole #dementia #inflammation

Without medical breakthroughs, more than 6.4M Australians will be diagnosed with dementia in the next 40 years at a cost of more than $1 trillion. This week ...

Magnesium----Comprehensive Guide. Forms of magnesium, benefits, dosages, impact on Vitamin D. Compilation videos----Magnesium MAGNESIUM🥑🥑 the Forgotten Mineral https://youtu.be/PhN6cYDWJ-0 Dr. Jin’s Top 5 MAGNESIUM🥑🥑 forms https://youtu.be/MJ024KxfQ0A Vitamin D and This Important Mineral (Magnesium) for Better Absorption https://youtu.be/I5rcDkYthUY MAGNESIUM and High Blood Pressure😡😡 https://youtu.be/SOBHPO0XhrU 😴😴SLEEP-My Top 5 Supplements. (CFS/ME) https://www.youtube.com/watch?v=un11PBe1PGw Signs and symptoms of magnesium deficiency *Muscle spasm or cramping *Sleep Disturbance *Stress/Anxiety *High blood pressure *Constipation *Fatigue *Heart Palpitations/Afib *Cognition *Headaches *Asthma *Preeclampsia **Magnesium assists in the activation of Vitamin D. **Co-factor in over 300 enzymatic reactions **4th most abundant mineral behind calcium, potassium, and sodium **25 (OH) D-------------------------------1,25 (OH) D inactive Magnesium active **1,25 (OH) also increases absorption of magnesium in GI tract Foods high in magnesium Avocado, almonds, dark chocolate, pumpkin seeds, spinach, Swiss Chard, Quinoa, Black Bean, Sunflower Seed, Flaxseed, Brazil nuts, bananas, salmon 1. Magnesium citrate-mg bound to citric acid found in fruits and contains antioxidant properties. Highly bio-available and easily absorbed in GI tract. Helps with migraines and constipation. 2. Magnesium glycinate-Mg and Glycine. Glycine is used in the body for protein production. Good for athletic performance and muscle recovery. Glycine is also a neurotransmitter so can help with sleep quality and duration and Depression 3. Magnesium sulfate-Epsom salt. Used in baths and absorbed in through the skin. IV-breathlessness and asthma, preeclampsia 4. Magnesium L-threonate-improve brain function such as memory and depression 5. Magnesium taurate-similar to Mg L-threonate in crossing BBB. Migraines, diabetes (insulin resistance). Some rate studies-delay onset and progression of cataracts Dr. Jin Sung is a Chiropractic Physician who specializes in the management of complex chronic conditions in Massachusetts, 30 minutes north of Boston. He utilizes natural and alternative therapies to help manage complex cases such as Hashimoto's, autoimmune conditions, IBS, SIBO, chronic fatigue, brain fog, early Alzheimer's, etc. www.DrJinSung.com https://www.facebook.com/DrJinWSung/ Office Contact 978 688-6999 www.drjinsung.com SEARCH on Dr. Sung's Online Store-https://us.fullscript.com/welcome/drjinsung Metagenics Magnesium Glycinate Metagenics Magnesium Citrate Xymogen's Magnesium Threonate Other search words Magnesium Taurate Magnesium Chloride Dr. Sung's Online Supplement Dispensary-conditions apply. Certain companies will require a prescription from Dr. Sung. The content of this video is for educational purposes only and does not constitute medical advise. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.

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The 10% trehalose spray improved salivary pH, unstimulated salivary flow rate, and the quality-of-life dimensions linked with physical, pain/discomfort, and psychological signs. The clinical efficacy of 10% trehalose spray was equivalent with CMC-based saliva substitutes for relieving radiation-indu …

Hempseed (Cannabis sativa) is one of the most promising sources of plant proteins. It contains approximately 24% (w/w) protein, and edestin accounts for approximately 60–80% (w/w) of its total proteins. In a framework of research aimed at fostering the proteins recovered from the press cake by-products generated after the extraction of hempseed oil, two hempseed protein hydrolysates (HH1 and HH2) were produced at an industrial level using a mixture of different enzymes from Aspergillus niger, Aspergillus oryzae, and Bacillus licheniformis for different times (5 h and 18 h). Using a combination of different direct antioxidant tests (DPPH, TEAC, FRAP, and ORAC assays, respectively), it has been demonstrated that HHs exert potent, direct antioxidant activity. A crucial feature of bioactive peptides is their intestinal bioavailability; for this reason, in order to solve this peculiar issue, the ability of HH peptides to be transported by differentiated human intestinal Caco-2 cells has been evaluated. Notably, by using mass spectrometry analysis (HPLC Chip ESI-MS/MS), the stable peptides transported by intestinal cells have been identified, and dedicated experiments confirmed that the trans-epithelial transported HH peptide mixtures retain their antioxidant activity, suggesting that these hempseed hydrolysates may be considered sustainable antioxidant ingredients to be exploited for further application, i.e., nutraceutical and/or food industries.

Niacin does more than lower cholesterol. It significantly increases lifespan in general, protecting against kidney disease, heart attacks, and cancer.